Resilience Phenotypes and Psychological Functioning among Individuals with Opioid Use Disorder.
Resilience
five factor model of personality
heroin
heterogeneity
opioid use disorder
Journal
Substance use & misuse
ISSN: 1532-2491
Titre abrégé: Subst Use Misuse
Pays: England
ID NLM: 9602153
Informations de publication
Date de publication:
2024
2024
Historique:
medline:
4
12
2023
pubmed:
27
9
2023
entrez:
27
9
2023
Statut:
ppublish
Résumé
Opioid use disorder (OUD) is a heterogeneous disorder. However, there is a lack of deep phenotyping investigations focusing on important psychological constructs such as resilience that may impact OUD. The present study aimed to investigate the relationship between trait resilience and the five-factor model of personality (FFM) among individuals with opioid use disorder (OUD). We also explored whether the FFM and trait resilience form specific phenotypes associated with psychological functioning. This secondary analysis of an epigenetic study included participants of African ancestry ( Linear regression revealed a significant relationship between resilience (CD-RISC-25 score) and the FFM, These findings suggest associations between the FFM and trait resilience among individuals with OUD. Two distinct "resilience phenotypes" emerged, with high-resilience individuals displaying less stress, anxiety, and depressive symptoms. Results highlight the clinical importance of resilience as a potential target for intervention in people with OUD.
Sections du résumé
BACKGROUND
UNASSIGNED
Opioid use disorder (OUD) is a heterogeneous disorder. However, there is a lack of deep phenotyping investigations focusing on important psychological constructs such as resilience that may impact OUD. The present study aimed to investigate the relationship between trait resilience and the five-factor model of personality (FFM) among individuals with opioid use disorder (OUD). We also explored whether the FFM and trait resilience form specific phenotypes associated with psychological functioning.
METHODS
UNASSIGNED
This secondary analysis of an epigenetic study included participants of African ancestry (
RESULTS
UNASSIGNED
Linear regression revealed a significant relationship between resilience (CD-RISC-25 score) and the FFM,
CONCLUSIONS
UNASSIGNED
These findings suggest associations between the FFM and trait resilience among individuals with OUD. Two distinct "resilience phenotypes" emerged, with high-resilience individuals displaying less stress, anxiety, and depressive symptoms. Results highlight the clinical importance of resilience as a potential target for intervention in people with OUD.
Identifiants
pubmed: 37752751
doi: 10.1080/10826084.2023.2259450
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
41-49Subventions
Organisme : NIDA NIH HHS
ID : T32 DA007294
Pays : United States