Can Pharmaceutical Excipients Threaten the Aquatic Environment? A Risk Assessment Based on the Microtox
CA model
Microtox®
aquatic toxicity
cardiovascular drugs
ecotoxicity
excipients
mixture toxicity
toxicity prediction
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
13 Sep 2023
13 Sep 2023
Historique:
received:
11
08
2023
revised:
10
09
2023
accepted:
11
09
2023
medline:
4
10
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
epublish
Résumé
The ecotoxicological impact of pharmaceuticals has received considerable attention, primarily focusing on active pharmaceutical ingredients (APIs) while largely neglecting the potential hazards posed by pharmaceutical excipients. Therefore, we analyzed the ecotoxicity of 16 commonly used pharmaceutical excipients, as well as 26 API-excipient and excipient-excipient mixtures utilizing the Microtox
Identifiants
pubmed: 37764366
pii: molecules28186590
doi: 10.3390/molecules28186590
pmc: PMC10535389
pii:
doi:
Substances chimiques
Excipients
0
Pharmaceutical Preparations
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
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