Cytokine profiles in an extremely preterm infant with congenital syphilis.
IL-12
IL-17
IL-2
congenital syphilis
cytokine
Journal
Fukushima journal of medical science
ISSN: 2185-4610
Titre abrégé: Fukushima J Med Sci
Pays: Japan
ID NLM: 0374626
Informations de publication
Date de publication:
15 Nov 2023
15 Nov 2023
Historique:
medline:
17
11
2023
pubmed:
28
9
2023
entrez:
28
9
2023
Statut:
ppublish
Résumé
We report the cytokine profiles of an infant with congenital syphilis as a first case. This female infant was born by vaginal delivery at a gestational age of 27 weeks during her mother's treatment for syphilis. Elevation of T helper (Th)-1 cytokines (interleukin (IL)-2, IL-12) and IL-17, which supports immunological mechanisms of Th-1, was similar to that in cases of syphilis in adults. IL-6 and granulocyte colony-stimulating factor (G-CSF), the synergistic effects of which cause the leukemoid reaction, were also elevated. The levels of interferon-γ and IL-17 in cerebral spinal fluid, which are elevated in neurosyphilis in adults, were slightly elevated.
Identifiants
pubmed: 37766559
doi: 10.5387/fms.2023-06
pmc: PMC10694514
doi:
Substances chimiques
Interleukin-17
0
Cytokines
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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