The sex-specific factor SOA controls dosage compensation in Anopheles mosquitoes.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
16
09
2022
accepted:
13
09
2023
medline:
3
11
2023
pubmed:
29
9
2023
entrez:
28
9
2023
Statut:
ppublish
Résumé
The Anopheles mosquito is one of thousands of species in which sex differences play a central part in their biology, as only females need a blood meal to produce eggs. Sex differentiation is regulated by sex chromosomes, but their presence creates a dosage imbalance between males (XY) and females (XX). Dosage compensation (DC) can re-equilibrate the expression of sex chromosomal genes. However, because DC mechanisms have only been fully characterized in a few model organisms, key questions about its evolutionary diversity and functional necessity remain unresolved
Identifiants
pubmed: 37769784
doi: 10.1038/s41586-023-06641-0
pii: 10.1038/s41586-023-06641-0
pmc: PMC10620080
doi:
Substances chimiques
Protein Isoforms
0
Insect Proteins
0
DNA-Binding Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
175-182Informations de copyright
© 2023. The Author(s).
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