Substance use and variation in sexual partnership rates among young MSM and young transgender women: Disaggregating between and within-person associations.
Men who have sex with men
Partnership rates
Substance use
Transgender women
Journal
Drug and alcohol dependence
ISSN: 1879-0046
Titre abrégé: Drug Alcohol Depend
Pays: Ireland
ID NLM: 7513587
Informations de publication
Date de publication:
01 11 2023
01 11 2023
Historique:
received:
03
05
2023
revised:
15
09
2023
accepted:
17
09
2023
pmc-release:
01
11
2024
medline:
30
10
2023
pubmed:
30
9
2023
entrez:
29
9
2023
Statut:
ppublish
Résumé
Substance use has been extensively linked to sexual behavior and HIV/STI risk among men who have sex with men (MSM) and transgender women (TW). However, the impact of specific substances and on specific partnership types is not well characterized. The current study seeks to estimate the association between specific substances and partnership rates while carefully disaggregating between and within-person associations to characterize the nature of these associations and inform prevention interventions. Using data from a longitudinal cohort (n = 1159) of young MSM (YMSM) and young TW (YTW), we utilized a series of hybrid mixed effect models to estimate the associations between substance use (i.e., heavy episodic drinking [HED], marijuana, cocaine, ecstasy, methamphetamine, poppers, prescription stimulant, prescription painkiller, and prescription depressants) and partnerships (i.e., one-time, casual, and main). Results from multivariable models indicated people using substances had higher one-time (HED, poppers) and casual (HED, methamphetamine, poppers) partnership rates. In addition, participants reported higher rates of one-time (HED, ecstasy, methamphetamine, poppers) and casual partners (HED, marijuana, cocaine, methamphetamines, poppers) during periods of substance use. These findings confirm that the highest rates of sexual activity occur among YMSM-YTW using substances during periods of substance use. Yet, these findings should caution researchers against simplistic generalizations as these associations differ across substance and partnership types. Efforts to promote the health of MSM-YTW who use substances should carefully consider this complexity as interventions accounting for the unique cultural context of substance use in these populations are most likely to be successful.
Sections du résumé
BACKGROUND
Substance use has been extensively linked to sexual behavior and HIV/STI risk among men who have sex with men (MSM) and transgender women (TW). However, the impact of specific substances and on specific partnership types is not well characterized. The current study seeks to estimate the association between specific substances and partnership rates while carefully disaggregating between and within-person associations to characterize the nature of these associations and inform prevention interventions.
METHODS
Using data from a longitudinal cohort (n = 1159) of young MSM (YMSM) and young TW (YTW), we utilized a series of hybrid mixed effect models to estimate the associations between substance use (i.e., heavy episodic drinking [HED], marijuana, cocaine, ecstasy, methamphetamine, poppers, prescription stimulant, prescription painkiller, and prescription depressants) and partnerships (i.e., one-time, casual, and main).
RESULTS
Results from multivariable models indicated people using substances had higher one-time (HED, poppers) and casual (HED, methamphetamine, poppers) partnership rates. In addition, participants reported higher rates of one-time (HED, ecstasy, methamphetamine, poppers) and casual partners (HED, marijuana, cocaine, methamphetamines, poppers) during periods of substance use.
CONCLUSION
These findings confirm that the highest rates of sexual activity occur among YMSM-YTW using substances during periods of substance use. Yet, these findings should caution researchers against simplistic generalizations as these associations differ across substance and partnership types. Efforts to promote the health of MSM-YTW who use substances should carefully consider this complexity as interventions accounting for the unique cultural context of substance use in these populations are most likely to be successful.
Identifiants
pubmed: 37774516
pii: S0376-8716(23)01206-1
doi: 10.1016/j.drugalcdep.2023.110968
pmc: PMC10615872
mid: NIHMS1935779
pii:
doi:
Substances chimiques
N-Methyl-3,4-methylenedioxyamphetamine
KE1SEN21RM
Methamphetamine
44RAL3456C
Cocaine
I5Y540LHVR
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
110968Subventions
Organisme : NIAID NIH HHS
ID : R01 AI138783
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA055502
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA036939
Pays : United States
Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest No conflicts to report.
Références
Int J Drug Policy. 2019 Jan;63:74-89
pubmed: 30513473
Clin Toxicol (Phila). 2023 Jan;61(1):39-46
pubmed: 36322622
Drug Alcohol Depend. 2015 Sep 1;154:199-207
pubmed: 26190557
J Acquir Immune Defic Syndr. 2021 Apr 15;86(5):552-561
pubmed: 33394814
J Acquir Immune Defic Syndr. 2020 Nov 1;85(3):272-279
pubmed: 32740370
BMC Public Health. 2011 Mar 25;11:189
pubmed: 21439069
J Acquir Immune Defic Syndr. 2020 May 1;84(1):e7-e10
pubmed: 32032305
AIDS Behav. 2013 Jul;17(6):2173-9
pubmed: 23128980
Youth Soc. 2019 Mar;51(2):219-246
pubmed: 30983642
Addict Behav. 2019 Jan;88:6-14
pubmed: 30099289
AIDS Behav. 2014 Oct;18(10):1981-90
pubmed: 24696227
AIDS Behav. 2021 Dec;25(Suppl 3):314-332
pubmed: 34148189
AIDS. 2013 Mar 13;27(5):815-23
pubmed: 23719351
Perspect Public Health. 2019 Jan;139(1):23-33
pubmed: 29846139
J Consult Clin Psychol. 2017 Jun;85(6):537-549
pubmed: 28394170
Drug Alcohol Depend. 2018 Aug 1;189:139-146
pubmed: 29944989
Psychol Methods. 2016 Jun;21(2):222-40
pubmed: 26690775
AIDS Behav. 2016 Mar;20(3):600-7
pubmed: 26400079
AIDS Behav. 2020 Jun;24(6):1966-1975
pubmed: 31858300
Am J Epidemiol. 2015 Aug 1;182(3):255-62
pubmed: 25995288
J Acquir Immune Defic Syndr. 2013 Nov 1;64(3):307-14
pubmed: 23846562
AIDS Behav. 2014 Jul;18(7):1359-67
pubmed: 24287786
Clin Psychol Rev. 2020 Dec;82:101924
pubmed: 33002795
Transgend Health. 2018 Dec 26;3(1):210-219
pubmed: 30596148
J Acquir Immune Defic Syndr. 2020 Aug 15;84(5):508-513
pubmed: 32692109
Addiction. 2020 Dec;115(12):2293-2302
pubmed: 32281718
AIDS. 2009 Jun 1;23(9):1153-62
pubmed: 19417579
Arch Sex Behav. 2018 Jan;47(1):259-271
pubmed: 28194606
Sex Health. 2017 Nov;14(6):523-532
pubmed: 28637581
Sex Transm Infect. 2008 Oct;84 Suppl 2:ii4-11
pubmed: 18799491
AIDS Behav. 2011 Apr;15(3):607-12
pubmed: 20376696
Int J Public Health. 2010 Jun;55(3):159-66
pubmed: 19949966
AIDS Behav. 2017 Oct;21(10):3026-3034
pubmed: 28702851
AIDS Behav. 2012 Apr;16(3):664-8
pubmed: 21505887
Subst Abuse Treat Prev Policy. 2019 Jan 3;14(1):1
pubmed: 30606266
Lancet HIV. 2022 Oct;9(10):e717-e725
pubmed: 35926550
Am J Public Health. 2010 Dec;100(12):2426-32
pubmed: 20966378
Pharmacol Biochem Behav. 2018 Jan;164:125-138
pubmed: 28843425
AIDS Educ Prev. 2013 Feb;25(1):62-71
pubmed: 23387952
Arch Sex Behav. 2021 Oct;50(7):2875-2886
pubmed: 34561794
Transgend Health. 2022 Aug 01;7(4):314-322
pubmed: 36033216
Curr Opin Infect Dis. 2016 Feb;29(1):58-63
pubmed: 26694620
Exp Clin Psychopharmacol. 2021 Dec;29(6):711-738
pubmed: 33001694
AIDS Behav. 2018 Jul;22(7):2199-2213
pubmed: 29633094
AIDS Behav. 2012 Aug;16(6):1394-410
pubmed: 22323004
AIDS Behav. 2016 Jun;20(6):1284-94
pubmed: 25861731
Curr HIV/AIDS Rep. 2013 Dec;10(4):314-23
pubmed: 24078370
Exp Clin Psychopharmacol. 2022 Apr;30(2):180-193
pubmed: 32986459
Addict Behav. 2020 Dec;111:106544
pubmed: 32717497
J Sex Res. 2019 May-Jun;56(4-5):409-424
pubmed: 30958036
Psychopharmacology (Berl). 2017 Feb;234(4):599-612
pubmed: 27921140
AIDS Care. 2023 Jun;35(6):791-799
pubmed: 34702087
Arch Sex Behav. 2021 Oct;50(7):2843-2860
pubmed: 33594529
BMC Infect Dis. 2022 Nov 14;22(1):850
pubmed: 36376835
Int J Environ Res Public Health. 2022 Feb 02;19(3):
pubmed: 35162728
PLoS One. 2014 Jul 16;9(7):e102894
pubmed: 25029514
Addiction. 2012 Jan;107(1):51-9
pubmed: 22151318
J Int AIDS Soc. 2015 Jan 16;18:19273
pubmed: 25609214
MMWR Morb Mortal Wkly Rep. 2022 Sep 02;71(35):1131-1135
pubmed: 36048619
BMC Infect Dis. 2019 Nov 11;19(1):958
pubmed: 31711433
AIDS Behav. 2014 Oct;18(10):1955-69
pubmed: 24906532
Health Psychol. 2011 Sep;30(5):597-605
pubmed: 21604883
J Public Health (Oxf). 2019 Mar 1;41(1):100-109
pubmed: 29474682
Subst Abuse Treat Prev Policy. 2022 Apr 9;17(1):27
pubmed: 35397571
J Int AIDS Soc. 2017 May 30;20(1):21585
pubmed: 28692211
J Acquir Immune Defic Syndr. 2019 Jan 1;80(1):24-30
pubmed: 30365451