Pulmonary phenotypes of bronchopulmonary dysplasia in the preterm infant.
Chronic lung disease
Hyperoxia
Lung injury
Premature lung
Ventilation
Journal
Seminars in perinatology
ISSN: 1558-075X
Titre abrégé: Semin Perinatol
Pays: United States
ID NLM: 7801132
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
medline:
20
11
2023
pubmed:
30
9
2023
entrez:
29
9
2023
Statut:
ppublish
Résumé
Bronchopulmonary dysplasia (BPD) remains the most common complication of premature birth, imposing a significant and potentially life-long burden on patients and their families. Despite advances in our understanding of the mechanisms that contribute to patterns of lung injury and dysfunctional repair, current therapeutic strategies remain non-specific with limited success. Contemporary definitions of BPD continue to rely on clinician prescribed respiratory support requirements at specific time points. While these criteria may be helpful in broadly identifying infants at higher risk of adverse outcomes, they do not offer any precise information regarding the degree to which each compartment of the lung is affected. In this review we will outline the different pulmonary phenotypes of BPD and discuss important features in the pathogenesis, clinical presentation, and management of these frequently overlapping scenarios.
Identifiants
pubmed: 37775367
pii: S0146-0005(23)00113-1
doi: 10.1016/j.semperi.2023.151810
pii:
doi:
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
151810Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.