Serum bilirubin levels in primary Sjögren's syndrome: an association with interstitial lung disease.
Interstitial lung disease
Primary Sjögren’s syndrome
Serum bilirubin
Journal
BMC pulmonary medicine
ISSN: 1471-2466
Titre abrégé: BMC Pulm Med
Pays: England
ID NLM: 100968563
Informations de publication
Date de publication:
30 Sep 2023
30 Sep 2023
Historique:
received:
19
08
2023
accepted:
22
09
2023
medline:
2
10
2023
pubmed:
1
10
2023
entrez:
30
9
2023
Statut:
epublish
Résumé
We aimed to assess the association between serum bilirubin levels and interstitial lung disease (ILD) in patients with Primary Sjögren's syndrome (pSS). The retrospectively analysis included 89 consecutive patients with pSS, we collected the clinical materials of pSS patients from the electronic medical records, and all pSS patients were divide into pSS with ILD group and pSS without ILD group. Serum bilirubin levels were significantly lower in pSS patients with ILD than those without ILD (p = 0.010). Serum bilirubin levels showed a significant negative correlation with erythrocyte sedimentation rate (ESR) (r = -0.321, p = 0.002) in patients with pSS. A multivariable logistic regression analysis confirmed that serum bilirubin presented an independent association with ILD in patients with pSS (OR = 0.841, 95%CI:0.728-0.972, p = 0.019). Serum bilirubin is independently associated with ILD and therefore may be a promising marker of ILD in patients with pSS.
Identifiants
pubmed: 37777728
doi: 10.1186/s12890-023-02672-5
pii: 10.1186/s12890-023-02672-5
pmc: PMC10543857
doi:
Substances chimiques
Bilirubin
RFM9X3LJ49
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
366Informations de copyright
© 2023. BioMed Central Ltd., part of Springer Nature.
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