IAEA/WHO postal dosimetry audit methodology for electron beams using radio photoluminescent dosimeters.


Journal

Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746

Informations de publication

Date de publication:
Nov 2023
Historique:
revised: 02 06 2023
received: 29 03 2023
accepted: 23 09 2023
medline: 6 11 2023
pubmed: 4 10 2023
entrez: 4 10 2023
Statut: ppublish

Résumé

Independent dosimetry audits are an important intervention in radiotherapy for quality assurance. Electron beams, used for superficial radiotherapy treatments, must also be tested in dosimetry audits as part of a good quality assurance program to help prevent clinical errors. To establish a new service for IAEA/WHO postal dosimetry audits in electron beams using RPL dosimeters. A novel postal audit methodology employing a PMMA holder system for RPLDs was developed. The associated correction factors including holder dependence, energy dependence, dose response non-linearity, and fading were obtained and tested in a multi-center (n = 12) pilot study. A measurement uncertainty budget was estimated and employed in analyzing the irradiated dosimeters. Holder and energy correction factors ranged from 1.004 to 1.010 and 1.019 to 1.059 respectively across the energy range. The non-linearity and fading correction models used for photon beams were tested in electron beams and did not significantly increase measurement uncertainty. The mean dose ratio ± SD of the multi-center study was 1.001 ± 0.011. The overall uncertainty budget was estimated as ± 1.42% (k = 1). A methodology for IAEA/WHO postal dosimetry audits in electron beams was developed and validated in a multi-center study and is now made available to radiotherapy centers as a routine service.

Sections du résumé

BACKGROUND BACKGROUND
Independent dosimetry audits are an important intervention in radiotherapy for quality assurance. Electron beams, used for superficial radiotherapy treatments, must also be tested in dosimetry audits as part of a good quality assurance program to help prevent clinical errors.
PURPOSE OBJECTIVE
To establish a new service for IAEA/WHO postal dosimetry audits in electron beams using RPL dosimeters.
METHODS METHODS
A novel postal audit methodology employing a PMMA holder system for RPLDs was developed. The associated correction factors including holder dependence, energy dependence, dose response non-linearity, and fading were obtained and tested in a multi-center (n = 12) pilot study. A measurement uncertainty budget was estimated and employed in analyzing the irradiated dosimeters.
RESULTS RESULTS
Holder and energy correction factors ranged from 1.004 to 1.010 and 1.019 to 1.059 respectively across the energy range. The non-linearity and fading correction models used for photon beams were tested in electron beams and did not significantly increase measurement uncertainty. The mean dose ratio ± SD of the multi-center study was 1.001 ± 0.011. The overall uncertainty budget was estimated as ± 1.42% (k = 1).
CONCLUSIONS CONCLUSIONS
A methodology for IAEA/WHO postal dosimetry audits in electron beams was developed and validated in a multi-center study and is now made available to radiotherapy centers as a routine service.

Identifiants

pubmed: 37793099
doi: 10.1002/mp.16776
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7214-7221

Informations de copyright

© 2023 The Authors. Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine.

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Auteurs

Alexis Dimitriadis (A)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Pavel Kazantsev (P)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Krzysztof Chelminski (K)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Egor Titovich (E)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Ekaterina Naida (E)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Talent Magnus (T)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Ahmed Meghzifene (A)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Godfrey Azangwe (G)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Mauro Carrara (M)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

Jamema Swamidas (J)

Dosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.

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