Myoglobin-loaded gadolinium nanotexaphyrins for oxygen synergy and imaging-guided radiosensitization therapy.

Humans Gadolinium Myoglobin Oxygen Radiation-Sensitizing Agents / pharmacology Neoplasms / diagnostic imaging Magnetic Resonance Imaging

Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
04 10 2023
Historique:
received: 30 11 2022
accepted: 12 09 2023
medline: 6 10 2023
pubmed: 5 10 2023
entrez: 4 10 2023
Statut: epublish

Résumé

Gadolinium (Gd

Identifiants

DOI: 10.1038/s41467-023-41782-w PMID: 37794000 PMC: PMC10550994
pubmed: 37794000
doi: 10.1038/s41467-023-41782-w
pii: 10.1038/s41467-023-41782-w
pmc: PMC10550994
doi:

Substances chimiques

Gadolinium AU0V1LM3JT
Myoglobin 0
Oxygen S88TT14065
Radiation-Sensitizing Agents 0
motexafin gadolinium 6433A42F4F

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

6187

Informations de copyright

© 2023. Springer Nature Limited.

Références

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Auteurs

Xiaotu Ma (X)

Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, P. R. China.
Department of Ultrasound, Peking University Third Hospital, 100191, Beijing, P. R. China.

Xiaolong Liang (X)

Department of Ultrasound, Peking University Third Hospital, 100191, Beijing, P. R. China.

Meinan Yao (M)

Medical Isotopes Research Center and Department of Radiation Medicine, State Key Laboratory of Natural and Biomimetic Drugs, School of Basic Medical Sciences, International Cancer Institute, Peking University, 100191, Beijing, P. R. China.

Yu Gao (Y)

Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, P. R. China.

Qi Luo (Q)

Guangzhou National Laboratory, 510005, Guangzhou, P.R. China.

Xiaoda Li (X)

Medical and Health Analysis Center, Peking University, 100191, Beijing, P. R. China.

Yue Yu (Y)

Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, P. R. China.

Yining Sun (Y)

Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, P. R. China.

Miffy H Y Cheng (MHY)

Princess Margaret Cancer Centre, University Health Network, Tronto, ON, M5G 1L7, Canada.
ORCID: 0000-0002-0261-4642

Juan Chen (J)

Princess Margaret Cancer Centre, University Health Network, Tronto, ON, M5G 1L7, Canada.

Gang Zheng (G)

Princess Margaret Cancer Centre, University Health Network, Tronto, ON, M5G 1L7, Canada. gang.zheng@uhnres.utoronto.ca.
Department of Medical Biophysics, University of Toronto, Tronto, ON, M5G 1L7, Canada. gang.zheng@uhnres.utoronto.ca.
ORCID: 0000-0002-0705-7398

Jiyun Shi (J)

Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, P. R. China. shijiyun@ibp.ac.cn.
ORCID: 0000-0001-7220-9637

Fan Wang (F)

Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, P. R. China. wangfan@bjmu.edu.cn.
Medical Isotopes Research Center and Department of Radiation Medicine, State Key Laboratory of Natural and Biomimetic Drugs, School of Basic Medical Sciences, International Cancer Institute, Peking University, 100191, Beijing, P. R. China. wangfan@bjmu.edu.cn.
Guangzhou National Laboratory, 510005, Guangzhou, P.R. China. wangfan@bjmu.edu.cn.
ORCID: 0000-0002-4166-5776

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Myoglobin-loaded gadolinium nanotexaphyrins...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Terres rares › Lanthanides › Gadolinium › Myoglobin-loaded gadolinium nanotexaphyrins...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Globines › Myoglobine › Myoglobin-loaded gadolinium nanotexaphyrins...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Oxygène › Myoglobin-loaded gadolinium nanotexaphyrins...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Radiosensibilisants › Myoglobin-loaded gadolinium nanotexaphyrins...
questionsmedicales.fr › Tumeurs › Myoglobin-loaded gadolinium nanotexaphyrins...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Myoglobin-loaded gadolinium nanotexaphyrins...