The Role of Serine/Threonine-Specific Protein Kinases in Cyanobacteria - SpkB Is Involved in Acclimation to Fluctuating Conditions in Synechocystis sp. PCC 6803.
CO(2)
H(2)O(2)
cyanobacteria
inorganic carbon
protein kinase
protein phosphorylation
stress
Journal
Molecular & cellular proteomics : MCP
ISSN: 1535-9484
Titre abrégé: Mol Cell Proteomics
Pays: United States
ID NLM: 101125647
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
10
03
2023
revised:
31
08
2023
accepted:
01
10
2023
medline:
27
11
2023
pubmed:
6
10
2023
entrez:
5
10
2023
Statut:
ppublish
Résumé
Protein phosphorylation via serine/threonine protein kinases (Spk) is a widespread mechanism to adjust cellular processes toward changing environmental conditions. To study their role(s) in cyanobacteria, we investigated a collection of 11 completely segregated spk mutants among the 12 annotated Spks in the model cyanobacterium Synechocystis sp. PCC 6803. Screening of the mutant collection revealed that especially the mutant defective in SpkB encoded by slr1697 showed clear deviations regarding carbon metabolism, that is, reduced growth rates at low CO
Identifiants
pubmed: 37797745
pii: S1535-9476(23)00167-6
doi: 10.1016/j.mcpro.2023.100656
pmc: PMC10651672
pii:
doi:
Substances chimiques
Protein Serine-Threonine Kinases
EC 2.7.11.1
Proteome
0
Threonine
2ZD004190S
Serine
452VLY9402
Bacterial Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
100656Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest The authors declare no competing interests.