Bi-HPDO3A as a novel contrast agent for X-ray computed tomography.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
05 10 2023
Historique:
received: 10 07 2023
accepted: 18 09 2023
medline: 1 11 2023
pubmed: 6 10 2023
entrez: 5 10 2023
Statut: epublish

Résumé

A new bismuth-based CT agent was synthesized through a facile synthesis strategy. The in vitro stability, toxicity and CT performance were evaluated. The in vivo imaging performance was investigated using three different doses (0.5, 1.2 and 5 mmol/kg) and the result obtained at 1.2 mmol/kg was compared with the clinically approved CT agent iopamidol at the same dosage.

Identifiants

pubmed: 37798332
doi: 10.1038/s41598-023-43031-y
pii: 10.1038/s41598-023-43031-y
pmc: PMC10556142
doi:

Substances chimiques

Contrast Media 0
Bismuth U015TT5I8H

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

16747

Informations de copyright

© 2023. Springer Nature Limited.

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Auteurs

Rebecca Rizzo (R)

Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Centre, University of Torino, Via Nizza 52, 10126, Turin, Italy.

Martina Capozza (M)

Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Centre, University of Torino, Via Nizza 52, 10126, Turin, Italy.

Carla Carrera (C)

Institute of Biostructures and Bioimaging, National Research Council, Via Nizza 52, 10126, Turin, Italy.

Enzo Terreno (E)

Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Centre, University of Torino, Via Nizza 52, 10126, Turin, Italy. enzo.terreno@unito.it.

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Classifications MeSH