Military Medicine and Medical Research as a Source of Inspiration and Innovation to Solve National Security and Health Challenges in the 21st Century.

Health research fatigue and stress human performance and resilience sensors

Journal

Pathogens & immunity
ISSN: 2469-2964
Titre abrégé: Pathog Immun
Pays: United States
ID NLM: 101683909

Informations de publication

Date de publication:
2023
Historique:
received: 23 05 2023
accepted: 07 07 2023
medline: 6 10 2023
pubmed: 6 10 2023
entrez: 6 10 2023
Statut: epublish

Résumé

The history of military medicine and research is rife with examples of novel treatments and new approaches to heal and cure soldiers and others impacted by war's devastation. In the 21st century, new threats, like climate change, are combined with traditional threats, like geopolitical conflict, to create novel challenges for our strategic interests. Extreme and inaccessible environments provide heightened risks for warfighter exposure to dangerous bacteria, viruses, and fungi, as well as exposure to toxic substances and extremes of temperature, pressure, or both providing threats to performance and eroding resilience. Back home, caring for our veterans is also a health-care priority, and the diseases of veterans increasingly overlap with the health needs of an aging society. These trends of climate change, politics, and demographics suggest performance evaluation and resilience planning and response are critical to assuring both warfighter performance and societal health. The Cleveland ecosystem, comprising several hospitals, a leading University, and one of the nation's larger Veteran's Health Administration systems, is ideal for incubating and understanding the response to these challenges. In this review, we explore the interconnections of collaborations between Defense agencies, particularly Air Force and Army and academic medical center-based investigators to drive responses to the national health security challenges facing the United States and the world.

Identifiants

pubmed: 37799210
doi: 10.20411/pai.v8i1.596
pii: pai.v8i1.596
pmc: PMC10550252
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

51-63

Informations de copyright

Copyright © 2023 Pathogens and Immunity.

Déclaration de conflit d'intérêts

MRC is a co-founder of Sensate Biosystems LLC, which is developing wearable sensors for performance monitoring. UAG has financial interests in Hemex Health Inc., BioChip Labs Inc., Xatec Inc., and DxNow Inc. These companies offer point-of-care diagnostics for hemoglobin disorders, anemia, and malaria; microfluidic biomarker assays for blood disorders; point-of-care global assays to evaluate the hemostatic process; microfluidic and bio-imaging technologies for IVF, forensics, and diagnostics. ASG is a co-founder, CTO, and Chair of Scientific Advisory Board for Haima Therapeutics LLC, a biotech company focused on the research and development of blood surrogate technologies.

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Auteurs

Nanak S Dhillon (NS)

Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, OH.
Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, Cleveland, Ohio.

Nayeon Jeon (N)

Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, OH.
Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, Cleveland, Ohio.

Umut A Gurkan (UA)

Department of Mechanical and Aerospace Engineering, Case School of Engineering, Case Western Reserve University, Cleveland, Ohio.

Anirban Sen Gupta (AS)

Department of Biomedical Engineering, School of Medicine, Case School of Engineering, Case Western Reserve University, Cleveland, Ohio.

Robert A Bonomo (RA)

Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center; Case Western Reserve University, Cleveland, OH; VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES); Departments of Medicine, Pharmacology, Molecular Biology and Microbiology, and Biochemistry, Case Western Reserve University, Cleveland, Ohio.

Lawrence F Drummy (LF)

Materials and Manufacturing Directorate, Air Force Research Laboratory, Dayton, Ohio.

Mei Zhang (M)

Department of Biomedical Engineering, School of Medicine, Case School of Engineering, Case Western Reserve University, Cleveland, Ohio.

Mark R Chance (MR)

Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, OH.
Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Department of Biomedical Engineering, School of Medicine, Case School of Engineering, Case Western Reserve University, Cleveland, Ohio.

Classifications MeSH