Mark R Chance

Affiliations

Center for Proteomics & Bioinformatics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.

Publications (28)

Fast Protein Footprinting by X-ray Mediated Radical Trifluoromethylation.

Journal of the American Society for Mass Spectrometry

Avec: Ming Cheng , Awuri Asuru , Janna Kiselar , George Mathai , Mark R Chance , Michael L Gross

Military Medicine and Medical Research as a Source of Inspiration and Innovation to Solve National Security and Health Challenges in the 21st Century.

Pathogens & immunity

Avec: Nanak S Dhillon , Nayeon Jeon , Umut A Gurkan , Anirban Sen Gupta , Robert A Bonomo , Lawrence F Drummy , Mei Zhang , Mark R Chance

Human alveolar macrophages display marked hypo-responsiveness to IFN-γ in both proteomic and gene expression analysis.

PloS one

Avec: Bonnie A Thiel , Kathleen C Lundberg , Daniela Schlatzer , Jessica Jarvela , Qing Li , Rachel Shaw , Scott M Reba , Shane Fletcher , Sara E Beckloff , Mark R Chance , W Henry Boom , Richard F Silver , Gurkan Bebek

Evaluating Mass Spectrometry-Based Hydroxyl Radical Protein Footprinting of a Benchtop Flash Oxidation System against a Synchrotron X-ray Beamline.

Journal of the American Society for Mass Spectrometry

Avec: Rohit Jain , Nanak S Dhillon , Vijaya Lakshmi Kanchustambham , David T Lodowski , Erik R Farquhar , Janna Kiselar , Mark R Chance

Methionine Sulfoxide Speciation in Mouse Hippocampus Revealed by Global Proteomics Exhibits Age- and Alzheimer's Disease-Dependent Changes Targeted to Mitochondrial and Glycolytic Pathways.

International journal of molecular sciences

Avec: Filipa Blasco Tavares Pereira Lopes , Daniela Schlatzer , Mengzhen Li , Serhan Yilmaz , Rihua Wang , Xin Qi , Marzieh Ayati , Mehmet Koyutürk , Mark R Chance

Mass Spectrometry-Based Protein Footprinting Defines the Binding Pocket of Crotonylated H3K14 in the PHD1 Domain of BAF45D within the BAF Chromatin Remodeling Complex.

ACS bio & med chem Au

Avec: Marissa R Martinez , Janna Kiselar , Benlian Wang , Dipti Sadalge , Laura Zawadzke , Asad Taherbhoy , Derek Musser , Yunji Davenport , Jeremy Setser , Mark R Chance , Steve Bellon

Exploring temporal and sex-linked dysregulation in Alzheimer disease phosphoproteome.

iScience

Avec: Serhan Yılmaz , Filipa Blasco Tavares Pereira Lopes , Daniela Schlatzer , Rihua Wang , Xin Qi , Mehmet Koyutürk , Mark R Chance

Interplay of transcriptional signaling by progesterone, cyclic AMP, and inflammation in myometrial cells: implications for the control of human parturition.

Molecular human reproduction

Avec: Zachary Stanfield , Peyvand Amini , Junye Wang , Lijuan Yi , Huiqing Tan , Mark R Chance , Mehmet Koyutürk , Sam Mesiano

A Metastable Contact and Structural Disorder in the Estrogen Receptor Transactivation Domain.

Structure (London, England : 1993)

Avec: Yi Peng , Shufen Cao , Janna Kiselar , Xiangzhu Xiao , Zhanwen Du , An Hsieh , Soobin Ko , Yinghua Chen , Prashansa Agrawal , Wenwei Zheng , Wuxian Shi , Wei Jiang , Lin Yang , Mark R Chance , Witold K Surewicz , Matthias Buck , Sichun Yang

Structurally distinct external solvent-exposed domains drive replication of major human prions.

PLoS pathogens

Avec: Mohammad Khursheed Siddiqi , Chae Kim , Tracy Haldiman , Miroslava Kacirova , Benlian Wang , Jen Bohon , Mark R Chance , Janna Kiselar , Jiri G Safar

Training the next generation of translational scientists: The Case Western Reserve University Translational Fellows Program.

Journal of clinical and translational science

Avec: Cheryl L Thompson , Tessianna A Misko , Mark R Chance

Functional characterization of co-phosphorylation networks.

Bioinformatics (Oxford, England)

Avec: Marzieh Ayati , Serhan Yılmaz , Mark R Chance , Mehmet Koyuturk

Exploring Temporal and Sex-Linked Dysregulation in Alzheimer's Disease Phospho-Proteome.

bioRxiv : the preprint server for biology

Avec: Serhan Yılmaz , Filipa Blasco Tavares Pereira Lopes , Daniela Schlatzer , Rihua Wang , Xin Qi , Mehmet Koyutürk , Mark R Chance

Making proteomics accessible: RokaiXplorer for interactive analysis of phospho-proteomic data.

Bioinformatics advances

Avec: Serhan Yılmaz , Filipa Blasco Tavares Pereira Lopes , Daniela Schlatzer , Marzieh Ayati , Mark R Chance , Mehmet Koyutürk

Proteins inform survival-based differences in patients with glioblastoma.

Neuro-oncology advances

Avec: L C Stetson , Quinn T Ostrom , Daniela Schlatzer , Peter Liao , Karen Devine , Kristin Waite , Marta E Couce , Peggy L R Harris , Amber Kerstetter-Fogle , Michael E Berens , Andrew E Sloan , Mohammad M Islam , Vilashini Rajaratnam , Shama P Mirza , Mark R Chance , Jill S Barnholtz-Sloan

The XFP (17-BM) beamline for X-ray footprinting at NSLS-II.

Journal of synchrotron radiation

Avec: Awuri Asuru , Erik R Farquhar , Michael Sullivan , Donald Abel , John Toomey , Mark R Chance , Jen Bohon

Protein Footprinting: Auxiliary Engine to Power the Structural Biology Revolution.

Journal of molecular biology

Avec: Mark R Chance , Erik R Farquhar , Sichun Yang , David T Lodowski , Janna Kiselar

Co-phosphorylation networks reveal subtype-specific signaling modules in breast cancer.

Bioinformatics (Oxford, England)

Avec: Marzieh Ayati , Mark R Chance , Mehmet Koyutürk

GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.

Science advances

Avec: Jonathan M Goodwin , Ward G Walkup , Kirsty Hooper , Taoyingnan Li , Chieko Kishi-Itakura , Aylwin Ng , Timothy Lehmberg , Archana Jha , Sravya Kommineni , Katherine Fletcher , Jorge Garcia-Fortanet , Yaya Fan , Qing Tang , Menghao Wei , Asmita Agrawal , Sagar R Budhe , Sreekanth R Rouduri , Dan Baird , Jeff Saunders , Janna Kiselar , Mark R Chance , Andrea Ballabio , Brent A Appleton , John H Brumell , Oliver Florey , Leon O Murphy

Robust inference of kinase activity using functional networks.

Nature communications

Avec: Serhan Yılmaz , Marzieh Ayati , Daniela Schlatzer , A Ercüment Çiçek , Mark R Chance , Mehmet Koyutürk

An engineered lactate oxidase based electrochemical sensor for continuous detection of biomarker lactic acid in human sweat and serum.

Heliyon

Avec: Qingrong He , Cheng Wang , Rohit Jain , James Byrnes , Erik R Farquhar , Elliot Reed , Elizabeth Berezovsky , Mark R Chance , David Lodowski , Ran An

Multiplex Chemical Labeling of Amino Acids for Protein Footprinting Structure Assessment.

Analytical chemistry

Avec: Rohit Jain , Nanak S Dhillon , Erik R Farquhar , Benlian Wang , Xiaolin Li , Janna Kiselar , Mark R Chance

Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer's Disease.

Molecular & cellular proteomics : MCP

Avec: Filipa Blasco Tavares Pereira Lopes , Daniela Schlatzer , Rihua Wang , Xiaolin Li , Emily Feng , Mehmet Koyutürk , Xin Qi , Mark R Chance

Intact mass spectrometry screening to optimize hydroxyl radical dose for protein footprinting.

Biochemical and biophysical research communications

Avec: Erik R Farquhar , Kanchustambham Vijayalakshmi , Rohit Jain , Benlian Wang , Janna Kiselar , Mark R Chance

Myometrial Transcriptional Signatures of Human Parturition.

Frontiers in genetics

Avec: Zachary Stanfield , Pei F Lai , Kaiyu Lei , Mark R Johnson , Andrew M Blanks , Roberto Romero , Mark R Chance , Sam Mesiano , Mehmet Koyutürk

Assembly of a GPCR-G Protein Complex.

Cell

Avec: Yang Du , Nguyen Minh Duc , Søren G F Rasmussen , Daniel Hilger , Xavier Kubiak , Liwen Wang , Jennifer Bohon , Hee Ryung Kim , Marcin Wegrecki , Awuri Asuru , Kyung Min Jeong , Jeongmi Lee , Mark R Chance , David T Lodowski , Brian K Kobilka , Ka Young Chung

CoPhosK: A method for comprehensive kinase substrate annotation using co-phosphorylation analysis.

PLoS computational biology

Avec: Marzieh Ayati , Danica Wiredja , Daniela Schlatzer , Sean Maxwell , Ming Li , Mehmet Koyutürk , Mark R Chance

Corrigendum: Myometrial Transcriptional Signatures of Human Parturition.

Frontiers in genetics

Avec: Zachary Stanfield , Pei F Lai , Kaiyu Lei , Mark R Johnson , Andrew M Blanks , Roberto Romero , Mark R Chance , Sam Mesiano , Mehmet Koyutürk

Réseau de co-auteurs

Mehmet Koyutürk 11 collaborations

Janna Kiselar 9 collaborations

Daniela Schlatzer 9 collaborations

Erik R Farquhar 6 collaborations

Marzieh Ayati 6 collaborations

Filipa Blasco Tavares Pereira Lopes 5 collaborations

Serhan Yılmaz 5 collaborations

Rohit Jain 4 collaborations

Rihua Wang 4 collaborations

Xin Qi 4 collaborations

Benlian Wang 4 collaborations

Awuri Asuru 3 collaborations

Nanak S Dhillon 3 collaborations

David T Lodowski 3 collaborations

Zachary Stanfield 3 collaborations

Sam Mesiano 3 collaborations

Sichun Yang 2 collaborations

Jen Bohon 2 collaborations

Xiaolin Li 2 collaborations

Pei F Lai 2 collaborations

Kaiyu Lei 2 collaborations

Mark R Johnson 2 collaborations

Andrew M Blanks 2 collaborations

Roberto Romero 2 collaborations

Ming Cheng 1 collaboration

George Mathai 1 collaboration

Michael L Gross 1 collaboration

Nayeon Jeon 1 collaboration

Umut A Gurkan 1 collaboration

Anirban Sen Gupta 1 collaboration

Robert A Bonomo 1 collaboration

Lawrence F Drummy 1 collaboration

Mei Zhang 1 collaboration

Bonnie A Thiel 1 collaboration

Kathleen C Lundberg 1 collaboration

Jessica Jarvela 1 collaboration

Qing Li 1 collaboration

Rachel Shaw 1 collaboration

Scott M Reba 1 collaboration

Shane Fletcher 1 collaboration

Sara E Beckloff 1 collaboration

W Henry Boom 1 collaboration

Richard F Silver 1 collaboration

Gurkan Bebek 1 collaboration

Vijaya Lakshmi Kanchustambham 1 collaboration

Mengzhen Li 1 collaboration

Serhan Yilmaz 1 collaboration

Marissa R Martinez 1 collaboration

Dipti Sadalge 1 collaboration

Laura Zawadzke 1 collaboration

Asad Taherbhoy 1 collaboration

Derek Musser 1 collaboration

Yunji Davenport 1 collaboration

Jeremy Setser 1 collaboration

Steve Bellon 1 collaboration

Peyvand Amini 1 collaboration

Junye Wang 1 collaboration

Lijuan Yi 1 collaboration

Huiqing Tan 1 collaboration

Yi Peng 1 collaboration

Shufen Cao 1 collaboration

Xiangzhu Xiao 1 collaboration

Zhanwen Du 1 collaboration

An Hsieh 1 collaboration

Soobin Ko 1 collaboration

Yinghua Chen 1 collaboration

Prashansa Agrawal 1 collaboration

Wenwei Zheng 1 collaboration

Wuxian Shi 1 collaboration

Wei Jiang 1 collaboration

Lin Yang 1 collaboration

Witold K Surewicz 1 collaboration

Matthias Buck 1 collaboration

Mohammad Khursheed Siddiqi 1 collaboration

Chae Kim 1 collaboration

Tracy Haldiman 1 collaboration

Miroslava Kacirova 1 collaboration

Jiri G Safar 1 collaboration

Cheryl L Thompson 1 collaboration

Tessianna A Misko 1 collaboration

Mehmet Koyuturk 1 collaboration

L C Stetson 1 collaboration

Quinn T Ostrom 1 collaboration

Peter Liao 1 collaboration

Karen Devine 1 collaboration

Kristin Waite 1 collaboration

Marta E Couce 1 collaboration

Peggy L R Harris 1 collaboration

Amber Kerstetter-Fogle 1 collaboration

Michael E Berens 1 collaboration

Andrew E Sloan 1 collaboration

Mohammad M Islam 1 collaboration

Vilashini Rajaratnam 1 collaboration

Shama P Mirza 1 collaboration

Jill S Barnholtz-Sloan 1 collaboration

Michael Sullivan 1 collaboration

Donald Abel 1 collaboration

John Toomey 1 collaboration

Jonathan M Goodwin 1 collaboration

Ward G Walkup 1 collaboration

Kirsty Hooper 1 collaboration

Taoyingnan Li 1 collaboration

Chieko Kishi-Itakura 1 collaboration

Aylwin Ng 1 collaboration

Timothy Lehmberg 1 collaboration

Archana Jha 1 collaboration

Sravya Kommineni 1 collaboration

Katherine Fletcher 1 collaboration

Jorge Garcia-Fortanet 1 collaboration

Yaya Fan 1 collaboration

Qing Tang 1 collaboration

Menghao Wei 1 collaboration

Asmita Agrawal 1 collaboration

Sagar R Budhe 1 collaboration

Sreekanth R Rouduri 1 collaboration

Dan Baird 1 collaboration

Jeff Saunders 1 collaboration

Andrea Ballabio 1 collaboration

Brent A Appleton 1 collaboration

John H Brumell 1 collaboration

Oliver Florey 1 collaboration

Leon O Murphy 1 collaboration

A Ercüment Çiçek 1 collaboration

Qingrong He 1 collaboration

Cheng Wang 1 collaboration

James Byrnes 1 collaboration

Elliot Reed 1 collaboration

Elizabeth Berezovsky 1 collaboration

David Lodowski 1 collaboration

Ran An 1 collaboration

Emily Feng 1 collaboration

Kanchustambham Vijayalakshmi 1 collaboration

Yang Du 1 collaboration

Nguyen Minh Duc 1 collaboration

Søren G F Rasmussen 1 collaboration

Daniel Hilger 1 collaboration

Xavier Kubiak 1 collaboration

Liwen Wang 1 collaboration

Jennifer Bohon 1 collaboration

Hee Ryung Kim 1 collaboration

Marcin Wegrecki 1 collaboration

Kyung Min Jeong 1 collaboration

Jeongmi Lee 1 collaboration

Brian K Kobilka 1 collaboration

Ka Young Chung 1 collaboration

Danica Wiredja 1 collaboration

Sean Maxwell 1 collaboration

Ming Li 1 collaboration