An engineered lactate oxidase based electrochemical sensor for continuous detection of biomarker lactic acid in human sweat and serum.

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
30 Jul 2024
Historique:
received: 24 06 2024
accepted: 08 07 2024
medline: 16 8 2024
pubmed: 16 8 2024
entrez: 16 8 2024
Statut: epublish

Résumé

Lactate levels in humans reveal intensity and duration of exertion and provide a critical readout for the severity of life-threatening illnesses such as pediatric sepsis. Using the lactate oxidase enzyme (Lox) from

Identifiants

DOI: 10.1016/j.heliyon.2024.e34301 PMID: 39149041 PMC: PMC11324829
pubmed: 39149041
doi: 10.1016/j.heliyon.2024.e34301
pii: S2405-8440(24)10332-5
pmc: PMC11324829
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e34301

Informations de copyright

© 2024 Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

The authors disclose that a provisional patent application related to the findings of this paper has been filed by Ran An, David Lodowski, and Mark Chance.

Auteurs

Qingrong He (Q)

Department of Biomedical Engineering, University of Houston, United States.

Cheng Wang (C)

Department of Biomedical Engineering, University of Houston, United States.

Rohit Jain (R)

Biomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, United States.
Center for Synchrotron Biosciences, School of Medicine, Case Western Reserve University, United States.

James Byrnes (J)

National Synchrotron Light Source II, Brookhaven National Laboratory, United States.

Erik R Farquhar (ER)

Biomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Center for Synchrotron Biosciences, School of Medicine, Case Western Reserve University, United States.

Elliot Reed (E)

Biomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Sensate Biosystems LLC, Cleveland, OH, United States.

Elizabeth Berezovsky (E)

Biomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Sensate Biosystems LLC, Cleveland, OH, United States.

Mark R Chance (MR)

Biomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, United States.
Center for Synchrotron Biosciences, School of Medicine, Case Western Reserve University, United States.
Sensate Biosystems LLC, Cleveland, OH, United States.

David Lodowski (D)

Biomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, United States.
Sensate Biosystems LLC, Cleveland, OH, United States.

Ran An (R)

Department of Biomedical Engineering, University of Houston, United States.
Biomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Department of Biomedical Sciences, University of Houston, United States.

Classifications MeSH