Towards real-time EPID-based 3D in vivo dosimetry for IMRT with Deep Neural Networks: A feasibility study.


Journal

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
ISSN: 1724-191X
Titre abrégé: Phys Med
Pays: Italy
ID NLM: 9302888

Informations de publication

Date de publication:
Oct 2023
Historique:
received: 12 03 2023
revised: 17 08 2023
accepted: 22 09 2023
medline: 3 11 2023
pubmed: 7 10 2023
entrez: 6 10 2023
Statut: ppublish

Résumé

We investigate the potential of the Deep Dose Estimate (DDE) neural network to predict 3D dose distributions inside patients with Monte Carlo (MC) accuracy, based on transmitted EPID signals and patient CTs. The network was trained using as input patient CTs and first-order dose approximations (FOD). Accurate dose distributions (ADD) simulated with MC were given as training targets. 83 pelvic CTs were used to simulate ADDs and respective EPID signals for subfields of prostate IMRT plans (gantry at 0

Identifiants

pubmed: 37801811
pii: S1120-1797(23)00175-8
doi: 10.1016/j.ejmp.2023.103148
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

103148

Informations de copyright

Copyright © 2023. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors have no relevant conflicts of interest to disclose.

Auteurs

Juliana Cristina Martins (JC)

Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, Garching b. München, 85748, Germany. Electronic address: Juliana.Martins@physik.uni-muenchen.de.

Joscha Maier (J)

German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany. Electronic address: joscha.maier@dkfz.de.

Chiara Gianoli (C)

Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, Garching b. München, 85748, Germany. Electronic address: Chiara.Gianoli@physik.uni-muenchen.de.

Sebastian Neppl (S)

Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, Munich, 81377, Germany. Electronic address: sebastian.neppl@uk-koeln.de.

George Dedes (G)

Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, Garching b. München, 85748, Germany. Electronic address: G.Dedes@physik.uni-muenchen.de.

Abdulaziz Alhazmi (A)

Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, Garching b. München, 85748, Germany. Electronic address: Aalhazmi@ksu.edu.sa.

Stella Veloza (S)

Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, Garching b. München, 85748, Germany. Electronic address: stella.veloza@cosylab.com.

Michael Reiner (M)

Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, Munich, 81377, Germany. Electronic address: Michael.Reiner@med.uni-muenchen.de.

Claus Belka (C)

Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, Munich, 81377, Germany. Electronic address: Claus.Belka@med.uni-muenchen.de.

Marc Kachelrieß (M)

German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany; Heidelberg University, Grabengasse 1, Heidelberg, 69117, Germany. Electronic address: marc.kachelriess@dkfz.de.

Katia Parodi (K)

Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, Garching b. München, 85748, Germany. Electronic address: Katia.Parodi@physik.uni-muenchen.de.

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