Angiotensin II type 2 receptor-mediated dilation is greater in the cutaneous microvasculature of premenopausal women compared with men.

Humans Female Male Receptor, Angiotensin, Type 2 Losartan / pharmacology Angiotensin II Dilatation Microvessels Vasoconstrictor Agents
angiotensin II microvasculature sex differences vasodilation

Journal

Journal of applied physiology (Bethesda, Md. : 1985)
ISSN: 1522-1601
Titre abrégé: J Appl Physiol (1985)
Pays: United States
ID NLM: 8502536

Informations de publication

Date de publication:
01 Dec 2023
Historique:
medline: 21 11 2023
pubmed: 12 10 2023
entrez: 12 10 2023
Statut: ppublish

Résumé

Differential activation of the renin-angiotensin system (RAS) likely contributes to sex differences in cardiovascular outcomes in premenopausal women compared with age-matched men. Women demonstrate reduced activation of the vasoconstrictor angiotensin II type 1 receptors (AT

Identifiants

DOI: 10.1152/japplphysiol.00382.2023 PMID: 37823205
pubmed: 37823205
doi: 10.1152/japplphysiol.00382.2023
doi:

Substances chimiques

Receptor, Angiotensin, Type 2 0
Losartan JMS50MPO89
Angiotensin II 11128-99-7
Vasoconstrictor Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1236-1242

Subventions

Organisme : HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI)
ID : HL-138133-05

Auteurs

Kelsey S Schwartz (KS)

Department of Health and Human Physiology, The University of Iowa, Iowa City, Iowa, United States.
ORCID: 0000-0002-1418-1813

James A Lang (JA)

Department of Kinesiology, Iowa State University, Ames, Iowa, United States.
ORCID: 0000-0002-5179-1434

Anna E Stanhewicz (AE)

Department of Health and Human Physiology, The University of Iowa, Iowa City, Iowa, United States.
ORCID: 0000-0002-3941-3879

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Angiotensin II type 2 receptor-mediated...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteurs aux angiotensines › Récepteur de type 2 à l'angiotensine-II › Angiotensin II type 2 receptor-mediated...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Tétrazoles › Losartan › Angiotensin II type 2 receptor-mediated...
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Autacoïdes › Angiotensines › Angiotensine-II › Angiotensin II type 2 receptor-mediated...
questionsmedicales.fr › Techniques d'investigation › Dilatation › Angiotensin II type 2 receptor-mediated...
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Microvaisseaux › Angiotensin II type 2 receptor-mediated...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents cardiovasculaires › Vasoconstricteurs › Angiotensin II type 2 receptor-mediated...