[Antibody drug conjugates (ADC) and bispecific antibodies in oncology - report of the 2022 Saint Louis day].
Anticorps monoclonaux conjugués et bispécifiques en cancérologie – compte rendu de la Journée de Saint Louis 2022.
Antibody drug conjugate
Anticorps bispécifique
Anticorps conjugué
Bispecific antibody
Pharmacocinétique
Pharmacokinetics
Journal
Bulletin du cancer
ISSN: 1769-6917
Titre abrégé: Bull Cancer
Pays: France
ID NLM: 0072416
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
23
03
2023
revised:
24
07
2023
accepted:
25
07
2023
medline:
1
12
2023
pubmed:
13
10
2023
entrez:
12
10
2023
Statut:
ppublish
Résumé
Antibody Drug Conjugates (ADC) and bispecific antibodies are booming and were the subject of the scientific event proposed by the French Society of Oncological Pharmacy, October 13, 2022. An ADC is composed of the antibody targeting a receptor expressed on the tumor cell, the spacer making it possible to attach the cytotoxic to the antibody and to control its distribution in the body, and the cytotoxic. Therapeutic antibodies, monoclonal and conjugated, have particular pharmacokinetics. Unlike monoclonal antibodies for which the standard dose is most often fixed, this is expressed in mg/m
Identifiants
pubmed: 37827964
pii: S0007-4551(23)00345-4
doi: 10.1016/j.bulcan.2023.07.009
pii:
doi:
Substances chimiques
glofitamab
06P3KLK2J8
Antibodies, Bispecific
0
Antineoplastic Agents
0
Immunoconjugates
0
Types de publication
Clinical Conference
English Abstract
Langues
fre
Sous-ensembles de citation
IM
Pagination
1343-1351Informations de copyright
Copyright © 2023 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.