Non-canonical food sources: bacterial metabolism of Maillard reaction products and its regulation.


Journal

Current opinion in microbiology
ISSN: 1879-0364
Titre abrégé: Curr Opin Microbiol
Pays: England
ID NLM: 9815056

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 20 07 2023
revised: 05 09 2023
accepted: 08 09 2023
medline: 27 11 2023
pubmed: 17 10 2023
entrez: 16 10 2023
Statut: ppublish

Résumé

Proteins are an important part of our regular diet. During food processing, their amino acid composition can be chemically altered by the reaction of free amino groups with sugars - a process termed glycation. The resulting Maillard reaction products (MRPs) have low bioavailability and thus predominantly end up in the colon where they encounter our gut microbiota. In the following review, we summarize bacterial strategies to efficiently metabolize these non-canonical amino acids. A particular focus will be on the complex regulatory mechanisms that allow a tightly controlled expression of metabolic genes to successfully occupy the ecological niches that result from the chemical diversity of MRPs.

Identifiants

pubmed: 37844449
pii: S1369-5274(23)00130-3
doi: 10.1016/j.mib.2023.102393
pii:
doi:

Substances chimiques

Glycation End Products, Advanced 0
Proteins 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102393

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Jürgen Lassak (J)

Fakultät für Biologie, Lehrstuhl Mikrobiologie/AG Mikrobielle Biochemie, Ludwig-Maximilians-Universität München, Großhaderner Str. 2, D-82152 Planegg-Martinsried, Germany. Electronic address: juergen.lassak@lmu.de.

Erica F Aveta (EF)

Fakultät für Biologie, Lehrstuhl Mikrobiologie/AG Mikrobielle Biochemie, Ludwig-Maximilians-Universität München, Großhaderner Str. 2, D-82152 Planegg-Martinsried, Germany.

Patroklos Vougioukas (P)

Fakultät Chemie und Lebensmittelchemie, Professur für Spezielle Lebensmittelchemie, Technische Universität Dresden, Bergstraße 66, D-01062 Dresden, Germany.

Michael Hellwig (M)

Fakultät Chemie und Lebensmittelchemie, Professur für Spezielle Lebensmittelchemie, Technische Universität Dresden, Bergstraße 66, D-01062 Dresden, Germany. Electronic address: michael.hellwig@tu-dresden.de.

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