Hypoxia-induced circ-CDYL-EEF1A2 transcriptional complex drives lung metastasis of cancer stem cells from hepatocellular carcinoma.
Humans
Animals
Mice
Carcinoma, Hepatocellular
/ pathology
Liver Neoplasms
/ pathology
Intercellular Adhesion Molecule-1
/ genetics
Cell Line, Tumor
Lung Neoplasms
/ metabolism
Hypoxia
/ genetics
Neoplastic Stem Cells
/ metabolism
Gene Expression Regulation, Neoplastic
MicroRNAs
/ genetics
Cell Proliferation
Tumor Microenvironment
Hydro-Lyases
/ genetics
Co-Repressor Proteins
/ genetics
Chromatin-RNA binding protein interaction
Circular RNA
Circulating cancer stem cell
Epithelial-mesenchymal transition
Preoperative detection
Journal
Cancer letters
ISSN: 1872-7980
Titre abrégé: Cancer Lett
Pays: Ireland
ID NLM: 7600053
Informations de publication
Date de publication:
01 12 2023
01 12 2023
Historique:
received:
15
08
2023
revised:
24
09
2023
accepted:
11
10
2023
medline:
20
11
2023
pubmed:
19
10
2023
entrez:
18
10
2023
Statut:
ppublish
Résumé
Hepatocellular carcinoma (HCC) is often associated with poor outcomes due to lung metastasis. ICAM-1
Identifiants
pubmed: 37852428
pii: S0304-3835(23)00393-2
doi: 10.1016/j.canlet.2023.216442
pii:
doi:
Substances chimiques
Intercellular Adhesion Molecule-1
126547-89-5
MicroRNAs
0
CDYL protein, human
EC 4.2.1.-
Hydro-Lyases
EC 4.2.1.-
Co-Repressor Proteins
0
EIF4A3 protein, human
EC 3.6.1.-
EEF1A2 protein, human
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
216442Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.