Neuronal cadherins: The keys that unlock layer-specific astrocyte identity?


Journal

The Journal of cell biology
ISSN: 1540-8140
Titre abrégé: J Cell Biol
Pays: United States
ID NLM: 0375356

Informations de publication

Date de publication:
06 11 2023
Historique:
medline: 2 11 2023
pubmed: 19 10 2023
entrez: 19 10 2023
Statut: ppublish

Résumé

An astrocyte's intricate morphology is essential for proper brain function, but the intrinsic and extrinsic cues that set astrocyte morphology are largely unknown. In this issue, Tan et al. (https://doi.org/10.1083/jcb.202303138) show that layer-specific expression of neuronal cadherins locally regulates astrocyte morphogenesis and heterogeneity.

Identifiants

pubmed: 37856080
pii: 276346
doi: 10.1083/jcb.202309050
pmc: PMC10587848
pii:
doi:

Substances chimiques

Cadherins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural Comment

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NINDS NIH HHS
ID : K99 NS121137
Pays : United States
Organisme : NINDS NIH HHS
ID : R00 NS121137
Pays : United States

Commentaires et corrections

Type : CommentOn

Informations de copyright

© 2023 Jetter and Ackerman.

Références

Curr Top Dev Biol. 2015;112:415-65
pubmed: 25733148
Neuron. 2009 Nov 12;64(3):320-7
pubmed: 19914181
Cell Adh Migr. 2015;9(3):202-13
pubmed: 25914083
Nat Commun. 2018 Apr 24;9(1):1623
pubmed: 29691400
Genes Dev. 2006 Dec 1;20(23):3199-214
pubmed: 17158740

Auteurs

Haley Jetter (H)

Department of Pathology and Immunology, Brain Immunology and Glia Center, Washington University School of Medicine, Saint Louis, MO, USA.

Sarah D Ackerman (SD)

Department of Pathology and Immunology, Brain Immunology and Glia Center, Washington University School of Medicine, Saint Louis, MO, USA.

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Classifications MeSH