The role of inflammation in autoimmune disease: a therapeutic target.
B cells
T cells
autoimmunity
inflammation
pro-inflammatory factors
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2023
2023
Historique:
received:
26
07
2023
accepted:
20
09
2023
medline:
23
10
2023
pubmed:
20
10
2023
entrez:
20
10
2023
Statut:
epublish
Résumé
Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are increasing year by year. AIDs are produced by the immune system's misidentification of self-antigens, seemingly caused by excessive immune function, but in fact they are the result of reduced accuracy due to the decline in immune system function, which cannot clearly identify foreign invaders and self-antigens, thus issuing false attacks, and eventually leading to disease. The occurrence of AIDs is often accompanied by the emergence of inflammation, and inflammatory mediators (inflammatory factors, inflammasomes) play an important role in the pathogenesis of AIDs, which mediate the immune process by affecting innate cells (such as macrophages) and adaptive cells (such as T and B cells), and ultimately promote the occurrence of autoimmune responses, so targeting inflammatory mediators/pathways is one of emerging the treatment strategies of AIDs. This review will briefly describe the role of inflammation in the pathogenesis of different AIDs, and give a rough introduction to inhibitors targeting inflammatory factors, hoping to have reference significance for subsequent treatment options for AIDs.
Identifiants
pubmed: 37859999
doi: 10.3389/fimmu.2023.1267091
pmc: PMC10584158
doi:
Substances chimiques
Inflammation Mediators
0
Autoantigens
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1267091Informations de copyright
Copyright © 2023 Xiang, Zhang, Jiang, Su and Shi.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Immunity. 2016 Jan 19;44(1):131-142
pubmed: 26750311
Curr Opin Rheumatol. 2010 May;22(3):246-51
pubmed: 20150813
Ann Rheum Dis. 2014 May;73(5):945-7
pubmed: 24336338
J Rheumatol. 2018 Jan;45(1):22-31
pubmed: 29093159
Clin Microbiol Rev. 2019 Jan 30;32(2):
pubmed: 30700431
Dermatol Ther (Heidelb). 2021 Aug;11(4):1319-1332
pubmed: 34060012
Curr Opin Immunol. 2002 Feb;14(1):111-6
pubmed: 11790540
Int J Mol Sci. 2021 Oct 30;22(21):
pubmed: 34769250
J Med Chem. 2020 Dec 10;63(23):15050-15071
pubmed: 33261314
Nat Commun. 2018 Feb 23;9(1):789
pubmed: 29476097
MAbs. 2014 May-Jun;6(3):774-82
pubmed: 24670876
Rheumatology (Oxford). 2012 Sep;51(9):1540-9
pubmed: 22577083
J Dermatolog Treat. 2023 Dec;34(1):2138691
pubmed: 36305633
Rheum Dis Clin North Am. 2004 May;30(2):329-47, vii
pubmed: 15172044
J Clin Invest. 2007 Mar;117(3):514-21
pubmed: 17332878
Ann Rheum Dis. 2004 May;63(5):508-16
pubmed: 15082480
Clin Exp Immunol. 2012 Aug;169(2):89-99
pubmed: 22774983
Immunity. 2006 Feb;24(2):179-89
pubmed: 16473830
Nat Med. 2020 Aug;26(8):1295-1306
pubmed: 32601335
Expert Opin Biol Ther. 2022 Feb;22(2):203-223
pubmed: 34314284
N Engl J Med. 2009 Aug 27;361(9):888-98
pubmed: 19710487
Gastroenterol Res Pract. 2016;2016:2097274
pubmed: 28070181
Semin Liver Dis. 2014 Aug;34(3):297-317
pubmed: 25057953
Int J Exp Pathol. 2014 Apr;95(2):131-7
pubmed: 24772480
Nat Immunol. 2019 Jul;20(7):928-942
pubmed: 31061532
RMD Open. 2021 May;7(2):
pubmed: 34011674
Cochrane Database Syst Rev. 2015 Apr 18;(4):CD005468
pubmed: 25887212
Br J Clin Pharmacol. 2022 Feb;88(4):1529-1550
pubmed: 34622969
J Am Acad Dermatol. 2022 Jul;87(1):95-102
pubmed: 35026342
MAbs. 2021 Jan-Dec;13(1):1964420
pubmed: 34460338
Immunity. 2001 Jun;14(6):661-4
pubmed: 11420036
Nat Rev Immunol. 2017 Jan;17(1):60-75
pubmed: 27916980
World J Pediatr. 2020 Feb;16(1):19-30
pubmed: 30796732
J Immunol. 2010 Sep 15;185(6):3472-80
pubmed: 20693421
Clin Rheumatol. 2023 Jun;42(6):1503-1520
pubmed: 36792848
J Intern Med. 2015 Oct;278(4):369-95
pubmed: 26212387
Clin Gastroenterol Hepatol. 2022 Mar;20(3):578-590.e4
pubmed: 33618023
Dermatol Ther (Heidelb). 2022 Aug;12(8):1777-1792
pubmed: 35798920
Front Immunol. 2020 Jul 21;11:1586
pubmed: 32793226
MAbs. 2010 Jul-Aug;2(4):428-39
pubmed: 20519961
Front Immunol. 2021 Mar 08;12:548469
pubmed: 33763057
Expert Rev Mol Diagn. 2021 Jul;21(7):685-702
pubmed: 34024239
Front Immunol. 2013 Oct 02;4:306
pubmed: 24106491
J Neuroimmunol. 2020 Feb 15;339:577115
pubmed: 31778849
J Eur Acad Dermatol Venereol. 2021 May;35(5):1143-1151
pubmed: 33617042
Acta Pharm Sin B. 2023 Sep;13(9):3930-3944
pubmed: 37719372
Ann Rheum Dis. 1991 Nov;50(11):776-81
pubmed: 1772292
Ann Rheum Dis. 2013 Apr;72 Suppl 2:ii116-23
pubmed: 23253932
Clin Immunol. 2010 Apr;135(1):156-66
pubmed: 20080065
Nat Commun. 2019 Dec 19;10(1):5795
pubmed: 31857588
Clin Rev Allergy Immunol. 2021 Feb;60(1):31-45
pubmed: 33185790
J Clin Invest. 2008 Jun;118(6):2269-80
pubmed: 18497880
Ann Rheum Dis. 1999 Nov;58 Suppl 1:I65-9
pubmed: 10577976
J Hepatol. 2004 Jul;41(1):31-7
pubmed: 15246204
Int J Mol Sci. 2019 Feb 15;20(4):
pubmed: 30769926
BMJ. 2020 Dec 2;371:m4328
pubmed: 33268527
Expert Opin Biol Ther. 2019 Oct;19(10):1031-1043
pubmed: 30574813
Int J Mol Sci. 2021 Oct 10;22(20):
pubmed: 34681582
N Engl J Med. 2018 May 17;378(20):1908-1919
pubmed: 29768139
Nat Med. 2012 Jul 01;18(7):1069-76
pubmed: 22772566
Lupus. 2001;10(1):23-31
pubmed: 11243506
Ann Rheum Dis. 2022 Feb;81(2):225-231
pubmed: 34911706
Nat Rev Rheumatol. 2017 Aug;13(8):495-502
pubmed: 28541299
Cytokine Growth Factor Rev. 2023 Feb;69:28-42
pubmed: 35871978
Med Res Rev. 2021 Nov;41(6):3023-3061
pubmed: 34288018
Hepatol Int. 2010 May 19;4(2):475-93
pubmed: 20827405
Immunity. 2019 Jan 15;50(1):212-224.e4
pubmed: 30650377
Biochem Pharmacol. 2022 Mar;197:114929
pubmed: 35065024
Drugs. 2018 Jun;78(9):929-940
pubmed: 29931592
Br J Dermatol. 2021 Dec;185(6):1124-1134
pubmed: 33913511
Br J Clin Pharmacol. 2020 Dec;86(12):2507-2518
pubmed: 32415720
Lancet. 2021 Apr 24;397(10284):1564-1575
pubmed: 33894834
Drug Des Devel Ther. 2021 Nov 04;15:4559-4574
pubmed: 34764638
Nat Med. 2022 Oct;28(10):2124-2132
pubmed: 36109639
Rheumatology (Oxford). 2021 Jul 1;60(7):3088-3098
pubmed: 30770920
Expert Opin Biol Ther. 2011 Dec;11(12):1663-8
pubmed: 21995322
J Autoimmun. 2018 Jul;91:23-33
pubmed: 29551295
Front Physiol. 2018 Aug 24;9:1177
pubmed: 30197602
Arthritis Res Ther. 2015 May 20;17:135
pubmed: 25994180
Biochem Biophys Res Commun. 2020 Feb 19;522(4):1030-1036
pubmed: 31818460
J Inflamm Res. 2021 Dec 17;14:6975-6991
pubmed: 34949934
Drugs Context. 2019 Apr 17;8:212570
pubmed: 31024633
Indian J Gastroenterol. 2013 Sep;32(5):330-4
pubmed: 23897517
J Clin Invest. 2015 Jun;125(6):2228-33
pubmed: 25893595
J Leukoc Biol. 2013 Apr;93(4):489-97
pubmed: 23271701
Front Immunol. 2021 Sep 24;12:738481
pubmed: 34630419
Ann Rheum Dis. 2022 Dec;81(12):1661-1668
pubmed: 36109142
Rheumatology (Oxford). 2023 May 2;62(5):1851-1859
pubmed: 36130275
RMD Open. 2021 Jan;7(1):
pubmed: 33526709
Lancet. 2022 May 28;399(10340):2031-2046
pubmed: 35644155
Front Immunol. 2022 Feb 22;13:853008
pubmed: 35273620
J Hepatol. 2015 Apr;62(1 Suppl):S100-11
pubmed: 25920079
Ther Clin Risk Manag. 2020 Sep 24;16:903-916
pubmed: 33061395
Gastroenterology. 2022 May;162(6):1650-1664.e8
pubmed: 35134323
Arthritis Rheum. 2012 May;64(5):1420-9
pubmed: 22144400
MAbs. 2011 Jan-Feb;3(1):49-60
pubmed: 21048425
Int J Med Sci. 2017 Jan 15;14(2):102-109
pubmed: 28260984
Arthritis Res Ther. 2019 Apr 18;21(1):101
pubmed: 30999929
Drugs. 2021 Mar;81(4):483-494
pubmed: 33661486
Clin Ther. 2004 Dec;26(12):1960-75
pubmed: 15823761
Biomolecules. 2020 Jan 13;10(1):
pubmed: 31940989
Int J Mol Sci. 2022 Dec 21;24(1):
pubmed: 36613560
N Engl J Med. 2022 Aug 25;387(8):715-726
pubmed: 36001712
J Am Acad Dermatol. 2022 Nov;87(5):937-954
pubmed: 35131402
Ann Transl Med. 2023 Feb 28;11(4):178
pubmed: 36923085
Asian-Australas J Anim Sci. 2020 Apr;33(4):670-677
pubmed: 31480155
Front Immunol. 2020 Aug 21;11:1894
pubmed: 32973785
Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16957-62
pubmed: 12482935
Clin Exp Rheumatol. 2002 Jul-Aug;20(4):535-8
pubmed: 12175109
Lancet Gastroenterol Hepatol. 2023 Jun;8(6):579-590
pubmed: 36933563
Immunol Lett. 2007 Jan 15;108(1):27-33
pubmed: 17129613
J Clin Pharmacol. 2021 May;61(5):714-724
pubmed: 33314148
CMAJ. 2014 Oct 21;186(15):E579-86
pubmed: 24566651
Transl Res. 2021 Jun;232:75-87
pubmed: 33453429
Lancet. 2017 Jul 1;390(10089):73-84
pubmed: 28110981
Lancet. 2023 Jan 28;401(10373):304-318
pubmed: 36442487
Autoimmun Rev. 2012 Nov;12(1):22-30
pubmed: 22878274
Clin Exp Pharmacol Physiol. 2020 Apr;47(4):628-639
pubmed: 31742738
MAbs. 2011 Nov-Dec;3(6):535-45
pubmed: 22123062
J Autoimmun. 2020 May;109:102421
pubmed: 32019685
Adv Ther. 2022 Jan;39(1):44-57
pubmed: 34757601
Int J Nanomedicine. 2007;2(1):39-47
pubmed: 17722511
Hum Vaccin Immunother. 2017 Sep 2;13(9):1972-1988
pubmed: 28841363
Clin Gastroenterol Hepatol. 2016 Aug;14(8):1120-1129.e6
pubmed: 27058635
Arthritis Rheumatol. 2015 Oct;67(10):2591-600
pubmed: 26138593
Arthritis Rheumatol. 2022 Nov;74(11):1776-1785
pubmed: 35729713
Arthritis Rheumatol. 2021 Feb;73(2):336-346
pubmed: 32783351
Drugs. 2017 Nov;77(17):1865-1879
pubmed: 29094311
J Autoimmun. 2022 Oct;132:102861
pubmed: 35872103
Diabetes Metab. 2016 Dec;42(6):453-456
pubmed: 27720360
Lancet. 2016 Oct 22;388(10055):2023-2038
pubmed: 27156434
Curr Cardiol Rep. 2022 Jan;24(1):23-30
pubmed: 34993745
J Med Chem. 2017 Apr 27;60(8):3511-3517
pubmed: 28300404
Nat Rev Nephrol. 2023 Aug;19(8):509-524
pubmed: 37165096
J Rheumatol. 2022 Apr;49(4):398-407
pubmed: 35105709
Nat Rev Drug Discov. 2021 Jan;20(1):39-63
pubmed: 33077936
BioDrugs. 2015 Apr;29(2):133-42
pubmed: 25822149
Front Immunol. 2020 Jul 21;11:1557
pubmed: 32849527
J Cell Physiol. 2021 Sep;236(9):6090-6100
pubmed: 33559242
Arthritis Rheumatol. 2016 Sep;68(9):2163-73
pubmed: 27059799
Nat Rev Dis Primers. 2018 Feb 08;4:18001
pubmed: 29417936
Semin Immunopathol. 2007 Sep;29(3):303-13
pubmed: 17805542
Curr Opin Rheumatol. 2001 Nov;13(6):505-11
pubmed: 11698729
Ann Rheum Dis. 2015 Sep;74(9):1739-47
pubmed: 25902790
Lancet. 2022 May 28;399(10340):2015-2030
pubmed: 35644154
Autoimmun Rev. 2015 Jun;14(6):555-63
pubmed: 25661979
J Clin Invest. 2011 Mar;121(3):966-75
pubmed: 21339647
Arthritis Res Ther. 2023 Apr 13;25(1):60
pubmed: 37055803
Nat Med. 2017 Aug;23(8):938-944
pubmed: 28714991
Clin Rev Allergy Immunol. 2008 Jun;34(3):345-7
pubmed: 18097774
MAbs. 2016;8(1):141-9
pubmed: 26390837
Molecules. 2023 Jan 09;28(2):
pubmed: 36677735
Lancet. 2020 May 9;395(10235):1496-1505
pubmed: 32386593
Front Immunol. 2022 May 26;13:846155
pubmed: 35720380
J Immunol. 2015 Jul 1;195(1):237-45
pubmed: 26026064
Rheumatology (Oxford). 2019 Apr 1;58(4):617-627
pubmed: 30517745
Cell. 2011 May 27;145(5):745-57
pubmed: 21565393
Curr Opin Rheumatol. 2000 Sep;12(5):391-8
pubmed: 10990175
Genes Immun. 2009 Jul;10(5):509-16
pubmed: 19279650
Clin Exp Immunol. 2019 Mar;195(3):310-321
pubmed: 30430560
J Autoimmun. 2010 Mar;34(2):121-6
pubmed: 19699611
Clin Gastroenterol Hepatol. 2020 Sep;18(10):2179-2191.e6
pubmed: 31945470
Cells. 2020 Apr 03;9(4):
pubmed: 32260219
Cell Death Dis. 2017 Dec 14;8(12):3219
pubmed: 29242564
Diabetes Care. 2012 Aug;35(8):1654-62
pubmed: 22699287
J Am Acad Dermatol. 2019 Jul;81(1):196-203
pubmed: 30926369
J Autoimmun. 2010 Jun;34(4):400-7
pubmed: 19889514
Clin Chest Med. 2010 Sep;31(3):415-22
pubmed: 20692536
Clin Rev Allergy Immunol. 2014 Oct;47(2):148-62
pubmed: 24420508
J Dent Res. 2019 Jun;98(6):713-719
pubmed: 30958728
Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14181-6
pubmed: 14615579
Expert Opin Biol Ther. 2019 Oct;19(10):1023-1030
pubmed: 30601098
Cytokine. 2019 Jul;119:182-187
pubmed: 30952065
Am J Reprod Immunol. 2004 Jul;52(1):19-26
pubmed: 15214938
Autoimmun Rev. 2014 Feb;13(2):108-13
pubmed: 24075959
Nat Immunol. 2018 Jul;19(7):665-673
pubmed: 29925983
Sci Transl Med. 2021 Oct 20;13(616):eabg1210
pubmed: 34669443
Cell Mol Immunol. 2021 Aug;18(8):1896-1903
pubmed: 32472023
Redox Biol. 2019 Jul;25:101122
pubmed: 30737171
J Inflamm Res. 2016 Apr 19;9:39-50
pubmed: 27143947
Mol Ther. 2019 Aug 7;27(8):1424-1435
pubmed: 31153827
Hum Vaccin Immunother. 2021 Jun 3;17(6):1586-1598
pubmed: 33369527
Br J Clin Pharmacol. 2011 Aug;72(2):270-81
pubmed: 21392075
Lancet. 2005 Jul 23-29;366(9482):321-31
pubmed: 16039337
Arthritis Res Ther. 2016 Jan 29;18:35
pubmed: 26831337
Ann Rheum Dis. 2014 Jun;73(6):1202-10
pubmed: 23687262
Rheumatology (Oxford). 2019 May 1;58(5):849-858
pubmed: 30590833
BioDrugs. 2016 Dec;30(6):607-617
pubmed: 27704400
Pharmacol Ther. 2013 Mar;137(3):283-97
pubmed: 23103332
Expert Rev Clin Immunol. 2020 Aug;16(8):745-750
pubmed: 32729361
Pharmacology. 2021;106(1-2):53-59
pubmed: 32674107
JAMA. 2021 Dec 21;326(23):2375-2384
pubmed: 34932077
Molecules. 2022 Apr 22;27(9):
pubmed: 35566047
Kaohsiung J Med Sci. 2022 Mar;38(3):187-195
pubmed: 35234358
Acta Derm Venereol. 2022 Apr 27;102:adv00698
pubmed: 35146532
Expert Rev Clin Immunol. 2018 Jul;14(7):539-547
pubmed: 29925278
Ann Rheum Dis. 2012 Jul;71(7):1183-9
pubmed: 22328739
Ann Intern Med. 2019 Jan 1;170(1):ITC1-ITC16
pubmed: 30596879
Lancet. 2017 Jun 10;389(10086):2304-2316
pubmed: 28502609
Immunity. 2019 Apr 16;50(4):796-811
pubmed: 30995500
J Dermatolog Treat. 2023 Dec;34(1):2200872
pubmed: 37166385
Lancet. 2013 Aug 31;382(9894):819-31
pubmed: 23993191
Clin Exp Immunol. 2019 May;196(2):215-225
pubmed: 30615197
Adv Drug Deliv Rev. 2016 Mar 1;98:86-98
pubmed: 26546466
Front Immunol. 2018 Jun 07;9:1250
pubmed: 29930551
Arthritis Rheumatol. 2022 Apr;74(4):654-664
pubmed: 34748286
Arthritis Rheumatol. 2015 Jan;67(1):51-62
pubmed: 25303306
Front Immunol. 2018 Apr 10;9:758
pubmed: 29692782
Clin Transl Gastroenterol. 2018 Jan 18;9(1):e132
pubmed: 29345635
PLoS Med. 2006 Aug;3(8):e297
pubmed: 16942393
Cytokine. 2013 Mar;61(3):693-703
pubmed: 23340181
Front Immunol. 2016 Feb 08;7:35
pubmed: 26904025
N Engl J Med. 2018 Mar 08;378(10):931-939
pubmed: 29514034
Front Immunol. 2022 Dec 16;13:1118180
pubmed: 36591294
Int J Mol Sci. 2018 Aug 24;19(9):
pubmed: 30149545
J Intern Med. 2013 Nov;274(5):480-9
pubmed: 23906036
Lancet. 2013 Oct 26;382(9902):1433-44
pubmed: 23768844
J Immunol. 2019 Mar 1;202(5):1350-1362
pubmed: 30674573
J Leukoc Biol. 2023 May 16;:
pubmed: 37192369
PLoS One. 2015 May 11;10(5):e0126277
pubmed: 25962072
Clin Immunol Immunopathol. 1989 Sep;52(3):421-34
pubmed: 2758698
Nat Rev Rheumatol. 2021 Jul;17(7):387-404
pubmed: 34113018
Gastroenterology. 2022 Feb;162(2):495-508
pubmed: 34748774
Autoimmun Rev. 2012 Aug;11(10):754-65
pubmed: 22387972
Front Pharmacol. 2023 Feb 16;14:1089272
pubmed: 36874005
Arthritis Rheumatol. 2017 May;69(5):1078-1089
pubmed: 27992693
Nat Immunol. 2013 Jun;14(6):536-42
pubmed: 23685824
Health Technol Assess. 2016 Apr;20(35):1-610
pubmed: 27140438
J Immunol Res. 2019 Feb 28;2019:7403796
pubmed: 30944837
Cytokine. 2011 Dec;56(3):537-43
pubmed: 21907587
Sci Signal. 2022 Nov 8;15(759):eabi8713
pubmed: 36346838
J Hepatol. 2012 Jul;57(1):125-32
pubmed: 22425700
Front Neuroendocrinol. 2014 Aug;35(3):347-69
pubmed: 24793874
PLoS One. 2019 Aug 14;14(8):e0220868
pubmed: 31412060
Front Immunol. 2023 May 25;14:1151977
pubmed: 37304299
N Engl J Med. 2001 Aug 2;345(5):340-50
pubmed: 11484692
Front Immunol. 2023 Apr 14;14:1149874
pubmed: 37122706
Pharmaceuticals (Basel). 2022 Apr 20;15(5):
pubmed: 35631330
Front Immunol. 2023 May 12;14:1125257
pubmed: 37251412
Annu Rev Med. 2023 Jan 27;74:339-352
pubmed: 35804480
J Med Life. 2019 Apr-Jun;12(2):113-122
pubmed: 31406511
Nat Rev Endocrinol. 2013 Nov;9(11):646-59
pubmed: 23959365
J Gene Med. 2009 Nov;11(11):1064-70
pubmed: 19688809
Rheumatology (Oxford). 2019 Feb 1;58(2):352-360
pubmed: 30376130
Hepatology. 2009 Jul;50(1):130-42
pubmed: 19437492
Annu Rev Pathol. 2014;9:273-85
pubmed: 24050623
Lancet Gastroenterol Hepatol. 2023 Apr;8(4):307-320
pubmed: 36738762
Arthritis Rheumatol. 2023 Jun;75(6):879-889
pubmed: 36512671
Nature. 2011 Jun 15;474(7351):307-17
pubmed: 21677747
Clin Exp Rheumatol. 2020 Jan-Feb;38(1):27-34
pubmed: 31025924
J Cell Mol Med. 2018 Jul;22(7):3308-3314
pubmed: 29664231
Nature. 2019 Jun;570(7760):246-251
pubmed: 31142839
Arch Med Res. 2006 Nov;37(8):921-32
pubmed: 17045106
Autoimmun Rev. 2011 Jun;10(8):464-8
pubmed: 21296192
J Immunol. 2016 May 15;196(10):4040-51
pubmed: 27183637
Arthritis Res Ther. 2019 Dec 5;21(1):269
pubmed: 31805989
Inflamm Allergy Drug Targets. 2008 Sep;7(3):203-10
pubmed: 18782028
Immunol Lett. 2018 Mar;195:83-87
pubmed: 29032187
Clin Exp Rheumatol. 2016 Jul-Aug;34(4 Suppl 98):39-44
pubmed: 27586802
Arthritis Rheum. 2013 Feb;65(2):481-91
pubmed: 23045159
JCI Insight. 2021 Sep 22;6(18):
pubmed: 34324441
J Control Release. 2018 Aug 10;283:280-289
pubmed: 29859232
BioDrugs. 2010 Dec 14;24 Suppl 1:3-14
pubmed: 21175228
Nat Rev Immunol. 2010 Feb;10(2):89-102
pubmed: 20081871
Front Immunol. 2021 Feb 02;11:594658
pubmed: 33603736
Therap Adv Gastroenterol. 2019 Jun 13;12:1756284819852535
pubmed: 31223341
BMJ. 2006 Sep 16;333(7568):581-5
pubmed: 16974012
Front Immunol. 2022 Jul 12;13:933468
pubmed: 35903091
Arthritis Res Ther. 2011 Jun 20;13(3):R95
pubmed: 21689402
Int J Immunopathol Pharmacol. 2016 Sep;29(3):386-97
pubmed: 27207443
Adv Ther. 2021 Aug;38(8):4366-4387
pubmed: 34250583
Ann Rheum Dis. 2021 Feb;80(2):185-193
pubmed: 33106286
Drugs. 2023 Jul;83(11):1045-1052
pubmed: 37389706
Arthritis Rheum. 2008 May;58(5):1318-23
pubmed: 18438852
J Autoimmun. 2020 Jun;110:102374
pubmed: 31812331
Clin Rev Allergy Immunol. 2015 Oct;49(2):163-76
pubmed: 25277817
J Autoimmun. 2018 Dec;95:133-143
pubmed: 30385083
Clin Exp Immunol. 2004 Aug;137(2):379-85
pubmed: 15270856
Biomed J. 2021 Apr;44(2):172-182
pubmed: 32798211
Expert Opin Biol Ther. 2005 Apr;5(4):601-6
pubmed: 15934837
J Investig Med. 2012 Dec;60(8):1151-6
pubmed: 23076162
Nature. 2010 Oct 21;467(7318):967-71
pubmed: 20962846
Arthritis Res Ther. 2012 Apr 11;14(2):R74
pubmed: 22494514
Arthritis Rheumatol. 2021 Dec;73(12):2206-2218
pubmed: 34423919
J Autoimmun. 2014 Feb-Mar;48-49:10-3
pubmed: 24461385
J Biomed Biotechnol. 2010;2010:465898
pubmed: 20625488
Ann Clin Transl Neurol. 2022 Jan;9(1):91-97
pubmed: 35040583
Arthritis Rheumatol. 2021 Jul;73(7):1189-1199
pubmed: 33452867
Nat Rev Rheumatol. 2019 Jan;15(1):9-17
pubmed: 30341437
Front Immunol. 2018 Jul 19;9:1612
pubmed: 30072988
Dermatol Ther (Heidelb). 2016 Jun;6(2):111-24
pubmed: 27221323
J Autoimmun. 2005 Aug;25(1):63-71
pubmed: 16005184
Ann Rheum Dis. 2015 Jun;74(6):1302-10
pubmed: 24573745
J Hepatol. 2014 Nov;61(5):1106-14
pubmed: 24882050
Nat Rev Rheumatol. 2016 Nov 22;12(12):716-730
pubmed: 27872476
Arthritis Res Ther. 2017 Jun 17;19(1):144
pubmed: 28623945