Tumor-reactive T helper cells in the context of vaccination against glioma.

Humans T-Lymphocytes, Helper-Inducer Glioma Antigens, Neoplasm Vaccination Epitopes Cancer Vaccines

Journal

Cancer cell
ISSN: 1878-3686
Titre abrégé: Cancer Cell
Pays: United States
ID NLM: 101130617

Informations de publication

Date de publication:
13 11 2023
Historique:
received: 21 05 2023
revised: 11 06 2023
accepted: 26 09 2023
medline: 16 11 2023
pubmed: 21 10 2023
entrez: 20 10 2023
Statut: ppublish

Résumé

With the advances in immunogenomics, the majority of tumor-specific antigens were found to be recognized by T helper cells (T

Identifiants

DOI: 10.1016/j.ccell.2023.09.013 PMID: 37863064
pubmed: 37863064
pii: S1535-6108(23)00329-X
doi: 10.1016/j.ccell.2023.09.013
pii:
doi:

Substances chimiques

Antigens, Neoplasm 0
Epitopes 0
Cancer Vaccines 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1829-1834

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests M.P. is a founder of Tcelltech GmbH. M.K., T.B., M.P., and L.B. are inventors of long peptide vaccines targeting mutant H3 and IDH1 and T cell receptors targeting glioblastoma-associated antigens.

Auteurs

Binghao Zhao (B)

CCU Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neuroscience, Heidelberg University, Mannheim, Germany; German Cancer Consortium (DKTK), DKFZ, core center, Heidelberg, Germany.

Michael Kilian (M)

CCU Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neuroscience, Heidelberg University, Mannheim, Germany; German Cancer Consortium (DKTK), DKFZ, core center, Heidelberg, Germany.

Theresa Bunse (T)

CCU Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neuroscience, Heidelberg University, Mannheim, Germany; German Cancer Consortium (DKTK), DKFZ, core center, Heidelberg, Germany.

Michael Platten (M)

CCU Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neuroscience, Heidelberg University, Mannheim, Germany; DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Germany; Helmholtz Institute of Translational Oncology Mainz (HI-TRON Mainz) - a Helmholtz Institute of the DKFZ, Mainz, Germany; German Cancer Consortium (DKTK), DKFZ, core center, Heidelberg, Germany; Immune Monitoring Unit, National Center for Tumor Diseases (NCT), Heidelberg, a partnership between DKFZ and University Hospital, Heidelberg, Germany.

Lukas Bunse (L)

CCU Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neuroscience, Heidelberg University, Mannheim, Germany; DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Germany; German Cancer Consortium (DKTK), DKFZ, core center, Heidelberg, Germany. Electronic address: l.bunse@dkfz.de.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Tumor-reactive T helper cells in the context...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T auxiliaires › Tumor-reactive T helper cells in the context...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Gliome › Tumor-reactive T helper cells in the context...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes néoplasiques › Tumor-reactive T helper cells in the context...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Immunisation › Vaccination › Tumor-reactive T helper cells in the context...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Épitopes › Tumor-reactive T helper cells in the context...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins anticancéreux › Tumor-reactive T helper cells in the context...