UK Kidney Association Clinical Practice Guideline: Sodium-Glucose Co-transporter-2 (SGLT-2) Inhibition in Adults with Kidney Disease 2023 UPDATE.


Journal

BMC nephrology
ISSN: 1471-2369
Titre abrégé: BMC Nephrol
Pays: England
ID NLM: 100967793

Informations de publication

Date de publication:
25 10 2023
Historique:
received: 25 04 2023
accepted: 19 09 2023
medline: 27 10 2023
pubmed: 26 10 2023
entrez: 25 10 2023
Statut: epublish

Résumé

Large placebo-controlled trials have demonstrated kidney and cardiovascular clinical benefits of SGLT-2 inhibitors. Data from the EMPA-KIDNEY and DELIVER trials and associated meta-analyses triggered an update to the UK Kidney Association Clinical Practice Guideline on Sodium-Glucose Co-transporter-2 (SGLT-2) Inhibition in Adults with Kidney Disease. We provide a summary of the full guideline and highlight the rationale for recent updates. The use of SGLT-2 inhibitors in people with specific medical conditions, including type 1 diabetes, kidney transplants, and people admitted to hospital with heart failure is also considered, along with Recommendations for future research and Recommendations for implementation. A full "lay" summary of the guidelines is provided as an appendix to ensure that these guidelines are accessible and understandable to people who are not medical professionals.

Identifiants

pubmed: 37880609
doi: 10.1186/s12882-023-03339-3
pii: 10.1186/s12882-023-03339-3
pmc: PMC10598949
doi:

Substances chimiques

Blood Glucose 0
Hypoglycemic Agents 0
Sodium-Glucose Transporter 2 Inhibitors 0

Types de publication

Journal Article Practice Guideline Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

310

Informations de copyright

© 2023. BioMed Central Ltd., part of Springer Nature.

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Auteurs

Alistair J Roddick (AJ)

The Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK.
Oxford Kidney Unit, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Alexa Wonnacott (A)

Wales Kidney Research Unit, Cardiff University, Cardiff, UK.

David Webb (D)

Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.

Angela Watt (A)

UKKA Patient Representative, Bristol, UK.

Michael A Watson (MA)

UKKA Patient Representative, Bristol, UK.

Natalie Staplin (N)

The Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK.

Alex Riding (A)

Royal Free London NHS Foundation Trust, London, UK.

Eirini Lioudaki (E)

Kings College Hospital NHS Trust, London, UK.

Apexa Kuverji (A)

John Walls Renal Unit, Glenfield Hospital, Leicester, UK.

Mohsen El Kossi (ME)

Doncaster Royal Infirmary, Doncaster, UK.

Patrick Holmes (P)

Primary Care Diabetes Society, Darlington, UK.

Matt Holloway (M)

East Kent Hospitals University NHS Foundation Trust, Canterbury, UK.

Donald Fraser (D)

Wales Kidney Research Unit, Cardiff University, Cardiff, UK.

Chris Carvalho (C)

North East London Integrated Care Board, London, UK.
Clinical Effectiveness Group, Queen Mary University of London, London, UK.

James O Burton (JO)

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

Sunil Bhandari (S)

Hull University Teaching Hospitals NHS Trust and Hull York Medical School, Hull, UK.

William G Herrington (WG)

The Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK.
Oxford Kidney Unit, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Andrew H Frankel (AH)

Imperial College Healthcare NHS Trust, London, UK. a.frankel@imperial.ac.uk.

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