Histone Methyltransferases G9a/


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
17 Oct 2023
Historique:
received: 01 09 2023
revised: 07 10 2023
accepted: 10 10 2023
medline: 30 10 2023
pubmed: 28 10 2023
entrez: 28 10 2023
Statut: epublish

Résumé

Changes in epigenetic programming have been proposed as being key events in the initiation and progression of childhood cancers. HMT euchromatic histone lysine methyltransferase 2 (G9a, EHMT2), which is encoded by the

Identifiants

pubmed: 37894922
pii: ijms242015242
doi: 10.3390/ijms242015242
pmc: PMC10607632
pii:
doi:

Substances chimiques

EHMT2 protein, human EC 2.1.1.43
Histocompatibility Antigens 0
Histone Methyltransferases EC 2.1.1.-
Histone-Lysine N-Methyltransferase EC 2.1.1.43
EHMT1 protein, human EC 2.1.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NCI NIH HHS
ID : N/A
Pays : United States

Références

Mol Neurobiol. 2017 Dec;54(10):7610-7619
pubmed: 27832522
Biochem J. 1993 Mar 15;290 ( Pt 3):811-8
pubmed: 8457211
JCI Insight. 2019 May 16;5:
pubmed: 31095524
Cell Rep. 2016 Apr 5;15(1):77-85
pubmed: 27052169
Front Oncol. 2020 May 27;10:818
pubmed: 32537432
Cancer Cell. 2003 Jan;3(1):89-95
pubmed: 12559178
Clin Cancer Res. 2021 Apr 15;27(8):2179-2189
pubmed: 33504555
PLoS One. 2014 Sep 08;9(9):e106962
pubmed: 25198515
Nature. 2015 Oct 29;526(7575):700-4
pubmed: 26466568
Genes Dev. 2005 Apr 1;19(7):815-26
pubmed: 15774718
Cancer Res. 2010 Oct 15;70(20):7830-40
pubmed: 20940408
Science. 1984 Jun 8;224(4653):1121-4
pubmed: 6719137
Cancer Cell. 2014 Nov 10;26(5):668-681
pubmed: 25453903
Clin Epigenetics. 2016 May 24;8:57
pubmed: 27222667
Nat Genet. 2013 Mar;45(3):279-84
pubmed: 23334666
Elife. 2018 May 10;7:
pubmed: 29745895
Curr Biol. 2003 Jul 15;13(14):1192-200
pubmed: 12867029
Pediatr Blood Cancer. 2021 May;68 Suppl 2:e28355
pubmed: 33818887
Oncogene. 2007 Jan 4;26(1):77-90
pubmed: 16799634
Genes Dev. 2012 Nov 15;26(22):2499-511
pubmed: 23105005
J Clin Oncol. 2015 Sep 20;33(27):3008-17
pubmed: 26304901
Mamm Genome. 2001 Dec;12(12):916-24
pubmed: 11707778
Mol Cell. 2022 Dec 15;82(24):4611-4626.e7
pubmed: 36476474
J Biol Chem. 2021 Nov;297(5):101276
pubmed: 34619147
Nat Genet. 2012 Nov;44(11):1199-206
pubmed: 23042116
Onco Targets Ther. 2018 Oct 15;11:6947-6956
pubmed: 30410352
J Med Chem. 2013 Nov 14;56(21):8931-42
pubmed: 24102134
Neuromolecular Med. 2022 Dec;24(4):392-398
pubmed: 35113321
Epigenetics Chromatin. 2022 Nov 21;15(1):36
pubmed: 36411491
Nat Rev Dis Primers. 2018 Jul 5;4(1):5
pubmed: 29977059
J Clin Oncol. 2009 May 1;27(13):2209-16
pubmed: 19307502
ISRN Oncol. 2011;2011:168712
pubmed: 22084725
Am J Respir Cell Mol Biol. 2018 Apr;58(4):449-460
pubmed: 29053336
Clin Cancer Res. 2012 May 15;18(10):2768-79
pubmed: 22589485
Mol Neurobiol. 2018 Sep;55(9):7242-7258
pubmed: 29397557
Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1307-16
pubmed: 25737553
Int J Mol Sci. 2021 Oct 19;22(20):
pubmed: 34681949
Cancer Cell. 2017 Jan 9;31(1):50-63
pubmed: 28073004
N Engl J Med. 2021 Jan 14;384(2):154-164
pubmed: 33497548
Biochem Biophys Res Commun. 2020 Mar 26;524(1):57-63
pubmed: 31980180
Oncogene. 2022 Apr;41(18):2638-2650
pubmed: 35354905
Anticancer Drugs. 2013 Jun;24(5):484-93
pubmed: 23466651
Front Immunol. 2015 Sep 25;6:487
pubmed: 26441991

Auteurs

Barbara Kunzler Souza (BK)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Epigenica Biosciences, Canoas 92035-000, Brazil.

Natalia Hogetop Freire (NH)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Children's Cancer Institute, Porto Alegre 90620-110, Brazil.

Thiago Santos Monteiro (TS)

Epigenica Biosciences, Canoas 92035-000, Brazil.

Alice Laschuk Herlinger (AL)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.

Mariane Jaeger (M)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Children's Cancer Institute, Porto Alegre 90620-110, Brazil.

Matheus G S Dalmolin (MGS)

National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Children's Cancer Institute, Porto Alegre 90620-110, Brazil.

Caroline Brunetto de Farias (CB)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Children's Cancer Institute, Porto Alegre 90620-110, Brazil.

Lauro Gregianin (L)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Children's Cancer Institute, Porto Alegre 90620-110, Brazil.
Department of Pediatrics, School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
Pediatric Oncology Service, Clinical Hospital, Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.

André T Brunetto (AT)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Children's Cancer Institute, Porto Alegre 90620-110, Brazil.

Algemir L Brunetto (AL)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Children's Cancer Institute, Porto Alegre 90620-110, Brazil.

Carol J Thiele (CJ)

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Rafael Roesler (R)

Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology-INCT BioOncoPed, Porto Alegre 90035-003, Brazil.
Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre 90035-003, Brazil.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH