Treatment of a Severe Form of Euglycemic Ketoacidosis in a Patient Treated with SGLT-2 Inhibitors with the Aid of Somatostatin.


Journal

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia
ISSN: 1724-5990
Titre abrégé: G Ital Nefrol
Pays: Italy
ID NLM: 9426434

Informations de publication

Date de publication:
31 Aug 2023
Historique:
medline: 3 11 2023
pubmed: 1 11 2023
entrez: 1 11 2023
Statut: epublish

Résumé

Currently, the use of SGLT2 inhibitors is becoming more widespread, both for their role in controlling diabetes, and for their pleiotropic effects on glomerular hyperfiltration and heart failure. Along with their positive effects, these drugs can lead to various complications, the most severe being euglycemic ketoacidosis. The clinical case we have reported precisely describes this potentially serious complication which occurred in a 47-year-old patient who had been on SGLT2 inhibitor therapy for 5 years. In the resolution of this case we used, in addition to standard therapy, the continuous infusion of somatostatin, resulting in a rapid resolution of ketoacidosis and an improvement in the clinical condition.

Identifiants

pubmed: 37910214
pii: 40-04-2023-04
pii:

Substances chimiques

Sodium-Glucose Transporter 2 Inhibitors 0
Somatostatin 51110-01-1

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright by Società Italiana di Nefrologia SIN, Rome,Italy.

Auteurs

Aristide Torre (A)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Nicola Bisogno (N)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Carmine Botta (C)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Antonella Caiazza (A)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Francesca D'Angelo (F)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Luigi Del Giudice (L)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Pio Fiorentini (P)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Luigi Marzano (L)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Rita Nigro (R)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Dario Sassone (D)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Paola Torre (P)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

Daniela Vicedomini (D)

U.O.C. di Nefrologia e Dialisi, Ospedale Umberto I, Nocera Inferiore (SA).

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Classifications MeSH