Diuretic, Natriuretic, And Ca2+-Sparing Effect Of The Alkaloid Boldine In Rats.


Journal

Drug research
ISSN: 2194-9387
Titre abrégé: Drug Res (Stuttg)
Pays: Germany
ID NLM: 101602406

Informations de publication

Date de publication:
Nov 2023
Historique:
medline: 9 11 2023
pubmed: 8 11 2023
entrez: 7 11 2023
Statut: ppublish

Résumé

Previous studies indicate the renal vasodilating effects of boldine, an alkaloid found in Wistar rats were used and the urine volume was noted for 8 h and further studied. The acute treatment at 0.1 and 0.3 mg/kg of boldine showed a diuretic, natriuretic, and Ca This study reveals the diuretic, natriuretic, Ca

Sections du résumé

BACKGROUND BACKGROUND
Previous studies indicate the renal vasodilating effects of boldine, an alkaloid found in
METHODS METHODS
Wistar rats were used and the urine volume was noted for 8 h and further studied.
RESULTS RESULTS
The acute treatment at 0.1 and 0.3 mg/kg of boldine showed a diuretic, natriuretic, and Ca
CONCLUSIONS CONCLUSIONS
This study reveals the diuretic, natriuretic, Ca

Identifiants

pubmed: 37935203
doi: 10.1055/a-2182-3665
doi:

Substances chimiques

Diuretics 0
boldine 8I91GE2769
Calcium SY7Q814VUP
Aporphines 0
Sodium 9NEZ333N27
Receptors, Muscarinic 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

513-519

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest to disclose.

Auteurs

Viviane Miranda Bispo Steimbach (VMB)

Postgraduate Program in Pharmaceutical Sciences, University of Vale do Itajaí (UNIVALI), Itajaí, Brazil.

Ritade Cássia Vilhena da Silva (RCV)

Postgraduate Program in Pharmaceutical Sciences, University of Vale do Itajaí (UNIVALI), Itajaí, Brazil.

Luísa Nathália Bolda Mariano (LNB)

Postgraduate Program in Pharmaceutical Sciences, University of Vale do Itajaí (UNIVALI), Itajaí, Brazil.

Mariana Zanovello (M)

Postgraduate Program in Pharmaceutical Sciences, University of Vale do Itajaí (UNIVALI), Itajaí, Brazil.

Anelise Felício Macarini (AF)

Postgraduate Program in Pharmaceutical Sciences, University of Vale do Itajaí (UNIVALI), Itajaí, Brazil.

Luisa Mota da Silva (LM)

Postgraduate Program in Pharmaceutical Sciences, University of Vale do Itajaí (UNIVALI), Itajaí, Brazil.

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Classifications MeSH