Autoimmune Hepatitis: Epidemiology, Subtypes, and Presentation.
Autoimmune diseases
Autoimmune hepatitis
Clinical presentation
Epidemiology
Subtypes
Journal
Clinics in liver disease
ISSN: 1557-8224
Titre abrégé: Clin Liver Dis
Pays: United States
ID NLM: 9710002
Informations de publication
Date de publication:
02 2024
02 2024
Historique:
medline:
13
11
2023
pubmed:
10
11
2023
entrez:
9
11
2023
Statut:
ppublish
Résumé
Autoimmune hepatitis (AIH) is a chronic immunologic disorder in which the immune system targets the liver. The disease has a genetic basis and this accounts for the epidemiologic variation observed in serologic testing and clinical presentation across different populations. The incidence of AIH increases with age into the 70s and seems to be increasing in prevalence. Most patients test positive for antinuclear antibody, ASMA, or anti-LKM but about 20% of patients do not have these serologic markers. At clinical presentation, patients may be asymptomatic, symptomatic, have acute liver failure, or decompensated cirrhosis.
Identifiants
pubmed: 37945151
pii: S1089-3261(23)00076-4
doi: 10.1016/j.cld.2023.06.002
pii:
doi:
Substances chimiques
Autoantibodies
0
Antibodies, Antinuclear
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-14Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.