Lipid metabolism reprogramming in cardiac fibrosis.

Humans Myocardium / metabolism Lipid Metabolism Metabolic Reprogramming Myocytes, Cardiac / metabolism Cardiomyopathies / metabolism Fibrosis Lipids
cardiac fibrosis epigenetic ferroptosis lipid metabolism

Journal

Trends in endocrinology and metabolism: TEM
ISSN: 1879-3061
Titre abrégé: Trends Endocrinol Metab
Pays: United States
ID NLM: 9001516

Informations de publication

Date de publication:
02 2024
Historique:
received: 06 07 2023
revised: 11 10 2023
accepted: 11 10 2023
medline: 15 2 2024
pubmed: 11 11 2023
entrez: 10 11 2023
Statut: ppublish

Résumé

Cardiac fibrosis is a critical pathophysiological process that occurs with diverse types of cardiac injury. Lipids are the most important bioenergy substrates for maintaining optimal heart performance and act as second messengers to transduce signals within cardiac cells. However, lipid metabolism reprogramming is a double-edged sword in the regulation of cardiomyocyte homeostasis and heart function. Moreover, lipids can exert diverse effects on cardiac fibrosis through different signaling pathways. In this review, we provide a brief overview of aberrant cardiac lipid metabolism and recent progress in pharmacological research targeting lipid metabolism alterations in cardiac fibrosis.

Identifiants

DOI: 10.1016/j.tem.2023.10.004 PMID: 37949734
pubmed: 37949734
pii: S1043-2760(23)00217-5
doi: 10.1016/j.tem.2023.10.004
pii:
doi:

Substances chimiques

Lipids 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

164-175

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare that there are no conflicts of interest.

Auteurs

Li-Chan Lin (LC)

Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.

Zhi-Yan Liu (ZY)

Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.

Jing-Jing Yang (JJ)

Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China. Electronic address: yangjingjing@ahmu.edu.cn.

Jian-Yuan Zhao (JY)

Institute for Developmental and Regenerative Cardiovascular Medicine, MOE-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. Electronic address: zhaojy@vip.163.com.

Hui Tao (H)

Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China; Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China. Electronic address: taohui@ahmu.edu.cn.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Lipid metabolism reprogramming in cardiac fibrosis.
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Myocarde › Lipid metabolism reprogramming in cardiac fibrosis.
questionsmedicales.fr › Métabolisme › Métabolisme lipidique › Lipid metabolism reprogramming in cardiac fibrosis.
questionsmedicales.fr › Cellules › Cellules musculaires › Myocytes cardiaques › Lipid metabolism reprogramming in cardiac fibrosis.
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Cardiomyopathies › Lipid metabolism reprogramming in cardiac fibrosis.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Lipid metabolism reprogramming in cardiac fibrosis.
questionsmedicales.fr › Lipides › Lipid metabolism reprogramming in cardiac fibrosis.