Molecular dynamics analysis of superoxide dismutase 1 mutations suggests decoupling between mechanisms underlying ALS onset and progression.

Amyotrophic lateral sclerosis Diseaseassociated SOD1 mutations Molecular dynamics (MD) simulations Performed principal component analysis Superoxide Dismutase type 1 (SOD1) Survival analysis

Journal

Computational and structural biotechnology journal
ISSN: 2001-0370
Titre abrégé: Comput Struct Biotechnol J
Pays: Netherlands
ID NLM: 101585369

Informations de publication

Date de publication:
2023
Historique:
received: 01 06 2023
revised: 15 09 2023
accepted: 15 09 2023
medline: 13 11 2023
pubmed: 13 11 2023
entrez: 13 11 2023
Statut: epublish

Résumé

Mutations in the superoxide dismutase 1 (

Identifiants

DOI: 10.1016/j.csbj.2023.09.016 PMID: 37954145 PMC: PMC10637862
pubmed: 37954145
doi: 10.1016/j.csbj.2023.09.016
pii: S2001-0370(23)00328-8
pmc: PMC10637862
doi:

Types de publication

Journal Article

Langues

eng

Pagination

5296-5308

Informations de copyright

© 2023 Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.

Déclaration de conflit d'intérêts

None.

Références

Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):954-8
pubmed: 7862672
Curr Neurol Neurosci Rep. 2006 Jan;6(1):37-46
pubmed: 16469270
Nucleic Acids Res. 2000 Jan 1;28(1):235-42
pubmed: 10592235
Nat Methods. 2020 Mar;17(3):261-272
pubmed: 32015543
Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2210-5
pubmed: 21257910
J Mol Biol. 2007 Jan 12;365(2):333-42
pubmed: 17070542
J Neurol Sci. 2006 Mar 15;242(1-2):67-9
pubmed: 16423367
Curr Protoc Bioinformatics. 2006 Oct;Chapter 5:Unit-5.6
pubmed: 18428767
Hum Mutat. 2012 Sep;33(9):1345-51
pubmed: 22753137
Proteins. 2010 Jun;78(8):1950-8
pubmed: 20408171
Brain. 2013 Aug;136(Pt 8):2342-58
pubmed: 23687121
J Biol Chem. 2006 Mar 10;281(10):6184-93
pubmed: 16407238
Commun Biol. 2022 Jan 6;5(1):20221
pubmed: 34992214
Biochemistry. 2004 May 4;43(17):4899-905
pubmed: 15109247
J Mol Graph. 1996 Feb;14(1):33-8, 27-8
pubmed: 8744570
Sci Rep. 2019 Jul 25;9(1):10826
pubmed: 31346243
J Biol Chem. 2016 Feb 19;291(8):4144-55
pubmed: 26694608
Biochem Biophys Res Commun. 2016 Sep 30;478(4):1634-9
pubmed: 27591900
Nucleic Acids Res. 1998 Apr 15;26(8):1939-46
pubmed: 9518486
Expert Rev Mol Diagn. 2020 Jul;20(7):703-714
pubmed: 32497448
Amyotroph Lateral Scler Frontotemporal Degener. 2017 Aug;18(5-6):457-463
pubmed: 28325066
Bioinformatics. 2013 Apr 1;29(7):845-54
pubmed: 23407358
Eur J Hum Genet. 2018 Oct;26(10):1537-1546
pubmed: 29955173
Q Rev Biophys. 2019 Nov 25;52:e12
pubmed: 31760962
J Mol Graph Model. 2022 Jan;110:108026
pubmed: 34653813
Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11263-7
pubmed: 17592131
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16398-403
pubmed: 21930926
Mol Neurodegener. 2011 Nov 17;6:77
pubmed: 22094223
Proteins. 1993 Dec;17(4):412-25
pubmed: 8108382
Front Neurol. 2019 May 21;10:527
pubmed: 31164862
J Biol Chem. 2009 Nov 6;284(45):30965-73
pubmed: 19635794
Bioinformatics. 2017 Feb 1;33(3):444-446
pubmed: 28158668
Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):E6939-E6945
pubmed: 27791136
Ann Neurol. 2009 Jan;65 Suppl 1:S3-9
pubmed: 19191304
Neurology. 2009 May 12;72(19):1634-9
pubmed: 19176896
Annu Rev Biochem. 2005;74:563-93
pubmed: 15952898
J Biomol Struct Dyn. 1996 Feb;13(4):615-25
pubmed: 8906882
J Biol Chem. 2002 May 3;277(18):15923-31
pubmed: 11854284
J Chem Theory Comput. 2008 Jan;4(1):116-22
pubmed: 26619985
Brain. 2019 Aug 1;142(8):2230-2237
pubmed: 31332433
J Chem Inf Model. 2020 Mar 23;60(3):1884-1891
pubmed: 32011881
PLoS Genet. 2018 Oct 8;14(10):e1007682
pubmed: 30296255
BMC Struct Biol. 2018 Feb 5;18(Suppl 1):1
pubmed: 29431095
Eur Neurol. 2007;58(1):57-8
pubmed: 17483589
Nat Rev Neurosci. 2001 Nov;2(11):806-19
pubmed: 11715057
PLoS One. 2017 May 4;12(5):e0177284
pubmed: 28472188
J Phys Chem Lett. 2019 Dec 19;10(24):7740-7744
pubmed: 31747286
Neuron. 2006 Oct 5;52(1):39-59
pubmed: 17015226
Bioinformatics. 2019 Aug 1;35(15):2569-2577
pubmed: 30535291
Acta Neuropathol. 2003 Dec;106(6):561-8
pubmed: 14517684
Arch Neurol. 2006 Feb;63(2):262-7
pubmed: 16476815
Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3620-5
pubmed: 24550511
Protein Sci. 2005 May;14(5):1201-13
pubmed: 15840828
Proc Natl Acad Sci U S A. 2006 May 2;103(18):7148-53
pubmed: 16636274
PLoS One. 2009;4(3):e5004
pubmed: 19325915
Amyotroph Lateral Scler. 2008 Aug;9(4):249-50
pubmed: 18608099
Amyotroph Lateral Scler Frontotemporal Degener. 2016 Oct - Nov;17(7-8):610-613
pubmed: 27348463
Nat Commun. 2022 Nov 12;13(1):6901
pubmed: 36371497
J Hum Genet. 2023 Mar;68(3):131-152
pubmed: 35691950
N Engl J Med. 2022 Sep 22;387(12):1099-1110
pubmed: 36129998
Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3617-22
pubmed: 12655070

Auteurs

Munishikha Kalia (M)

Department of Biostatistics and Health Informatics, King's College London, London, UK.
Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.

Mattia Miotto (M)

Center for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Rome, Italy.

Deborah Ness (D)

Department of Biostatistics and Health Informatics, King's College London, London, UK.
Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.

Sarah Opie-Martin (S)

Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.

Thomas P Spargo (TP)

Department of Biostatistics and Health Informatics, King's College London, London, UK.
Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.

Lorenzo Di Rienzo (L)

Center for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Rome, Italy.

Tommaso Biagini (T)

Bioinformatics Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, S. Giovanni Rotondo, Italy.

Francesco Petrizzelli (F)

Bioinformatics Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, S. Giovanni Rotondo, Italy.

Ahmad Al Khleifat (A)

Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.

Renata Kabiljo (R)

Department of Biostatistics and Health Informatics, King's College London, London, UK.
Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.

Tommaso Mazza (T)

Bioinformatics Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, S. Giovanni Rotondo, Italy.

Giancarlo Ruocco (G)

Center for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Rome, Italy.
Department of Physics, Sapienza University, Piazzale Aldo Moro 5, 00185, Rome, Italy.

Edoardo Milanetti (E)

Center for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Rome, Italy.
Department of Physics, Sapienza University, Piazzale Aldo Moro 5, 00185, Rome, Italy.

Richard Jb Dobson (RJ)

Department of Biostatistics and Health Informatics, King's College London, London, UK.
Institute of Health Informatics, University College London, London, UK.
National Institute for Health Research Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust King's College London, London, United Kingdom.

Ammar Al-Chalabi (A)

Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.
Clinical Neurosciences, King's College Hospital, Denmark Hill, London, UK.

Alfredo Iacoangeli (A)

Department of Biostatistics and Health Informatics, King's College London, London, UK.
Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.
National Institute for Health Research Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust King's College London, London, United Kingdom.

Classifications MeSH