Understanding Cysteine Reactivity in Protein Environments with Electric Fields.

Cysteine / chemistry Hydrogen-Ion Concentration Proteins Sulfhydryl Compounds / chemistry Molecular Dynamics Simulation

Journal

The journal of physical chemistry. B
ISSN: 1520-5207
Titre abrégé: J Phys Chem B
Pays: United States
ID NLM: 101157530

Informations de publication

Date de publication:
23 Nov 2023
Historique:
medline: 24 11 2023
pubmed: 14 11 2023
entrez: 14 11 2023
Statut: ppublish

Résumé

The role cysteine residues play in proteins is mediated by their protonation state, whereby the thiolate form of the side chain is highly reactive while the thiol form is more inert. However, the p

Identifiants

DOI: 10.1021/acs.jpcb.3c05749 PMID: 37962274
pubmed: 37962274
doi: 10.1021/acs.jpcb.3c05749
doi:

Substances chimiques

Cysteine K848JZ4886
Proteins 0
Sulfhydryl Compounds 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

9936-9942

Auteurs

Valerie Vaissier Welborn (V)

Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24060, United States.
Macromolecules Innovation Institute (MII),Virginia Tech, Blacksburg, Virginia 24060, United States.
ORCID: 0000-0003-0834-4441

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés soufrés › Cystéine › Understanding Cysteine Reactivity in Protein...
questionsmedicales.fr › Phénomènes chimiques › Concentration en ions d'hydrogène › Understanding Cysteine Reactivity in Protein...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Understanding Cysteine Reactivity in Protein...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Thiols › Understanding Cysteine Reactivity in Protein...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Understanding Cysteine Reactivity in Protein...