Journal

Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359

Informations de publication

Date de publication:
2023
Historique:
received: 03 05 2023
accepted: 08 09 2023
medline: 16 11 2023
pubmed: 15 11 2023
entrez: 15 11 2023
Statut: epublish

Résumé

A strong epidemiologic link exists between cigarette smoke (CS) exposure and susceptibility to tuberculosis (TB). Macrophage and murine studies showed that CS and nicotine impair host-protective immune cells against We investigated whether CS-exposed Tregs could exacerbate We found that exposure of primary human Tregs to CS extract impaired the ability of unexposed human macrophages to control an Previous studies demonstrated that CS impairs macrophages and host-protective T effector cells in controlling

Identifiants

pubmed: 37965256
doi: 10.3389/fcimb.2023.1216492
pmc: PMC10641287
doi:

Substances chimiques

Nicotine 6M3C89ZY6R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1216492

Informations de copyright

Copyright © 2023 Bai, Verma, Garcia, Musheyev, Kim, Fornis, Griffith, Li, Whittel, Gadwa, Ohanjanyan, Eggleston, Galvan, Freed, Ordway and Chan.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Xiyuan Bai (X)

Department of Academic Affairs, National Jewish Health, Denver, CO, United States.
Department of Medicine, National Jewish Health, Denver, CO, United States.
Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Deepshikha Verma (D)

Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.

Cindy Garcia (C)

Department of Academic Affairs, National Jewish Health, Denver, CO, United States.
Department of Medicine, National Jewish Health, Denver, CO, United States.

Ariel Musheyev (A)

Department of Academic Affairs, National Jewish Health, Denver, CO, United States.
Department of Medicine, National Jewish Health, Denver, CO, United States.

Kevin Kim (K)

Department of Academic Affairs, National Jewish Health, Denver, CO, United States.
Department of Medicine, National Jewish Health, Denver, CO, United States.

Lorelenn Fornis (L)

Department of Academic Affairs, National Jewish Health, Denver, CO, United States.
Department of Medicine, National Jewish Health, Denver, CO, United States.

David E Griffith (DE)

Department of Academic Affairs, National Jewish Health, Denver, CO, United States.
Department of Medicine, National Jewish Health, Denver, CO, United States.

Li Li (L)

Department of Academic Affairs, National Jewish Health, Denver, CO, United States.
Department of Medicine, National Jewish Health, Denver, CO, United States.

Nicholas Whittel (N)

Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.

Jacob Gadwa (J)

Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.

Tamara Ohanjanyan (T)

Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.

Matthew J Eggleston (MJ)

Complement Laboratory, Advance Diagnostics, National Jewish Health, Denver, CO, United States.

Manuel Galvan (M)

Complement Laboratory, Advance Diagnostics, National Jewish Health, Denver, CO, United States.

Brian M Freed (BM)

Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Diane Ordway (D)

Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.

Edward D Chan (ED)

Department of Academic Affairs, National Jewish Health, Denver, CO, United States.
Department of Medicine, National Jewish Health, Denver, CO, United States.
Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Department of Medicine, Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, CO, United States.

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Classifications MeSH