Early detection of the emerging SARS-CoV-2 BA.2.86 lineage through integrated genomic surveillance of wastewater and COVID-19 cases in Sweden, weeks 31 to 38 2023.
BA.2.86
Freyja
SARS-CoV-2
Sweden
wastewater surveillance
whole genome sequencing
Journal
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
medline:
20
11
2023
pubmed:
17
11
2023
entrez:
16
11
2023
Statut:
ppublish
Résumé
The SARS-CoV-2 BA.2.86 Omicron subvariant was first detected in wastewater in Sweden in week 31 2023, using 21 highly specific markers from the 50 investigated. We report BA.2.86's introduction and subsequent spread to all 14 regions performing wastewater sampling, and on 70 confirmed COVID-19 cases, along with the emergence of sublineages JN.1 and JN.2. Further, we investigated two novel mutations defining the unique BA.2.86 branching in Sweden. Our integrated approach enabled variant tracking, offering evidence for well-informed public health interventions.
Identifiants
pubmed: 37971659
doi: 10.2807/1560-7917.ES.2023.28.46.2300595
pmc: PMC10655203
doi:
Substances chimiques
Wastewater
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
China CDC Wkly. 2021 Dec 3;3(49):1049-1051
pubmed: 34934514
Euro Surveill. 2023 Sep;28(36):
pubmed: 37676147
Nat Biotechnol. 2022 Dec;40(12):1814-1822
pubmed: 35851376
Lancet Infect Dis. 2023 Nov;23(11):e457-e459
pubmed: 37738994
N Engl J Med. 2023 Oct 26;389(17):1626-1628
pubmed: 37888924
Mol Biol Evol. 2021 Dec 9;38(12):5819-5824
pubmed: 34469548
Nature. 2022 Sep;609(7925):101-108
pubmed: 35798029