Phytochemical analysis and biological activities of essential oils extracted from Origanum grossii and Thymus pallidus: in vitro and in silico analysis.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
16 11 2023
Historique:
received: 12 06 2023
accepted: 10 11 2023
medline: 20 11 2023
pubmed: 17 11 2023
entrez: 17 11 2023
Statut: epublish

Résumé

The study aimed at investigating the phytochemical composition, antioxidant and antibacterial activities of essential oils (EOs) of Origanum grossii and Thymus pallidus. The selection of these plants for the study was driven by a comprehensive survey conducted in the Ribat Elkheir region of Morocco, where these plants are widely utilized. The results reflect the valorization of these plants based on the findings of the regional survey. The GC-MS phytochemical analysis revealed that the main constituents of the essential oil were carvacrol and thymol for O. grossii and T. pallidus respectively. Quantitative assays demonstrated that O. grossii exhibited higher levels of polyphenols (0.136 mg AGE/mg EO) and flavonoids (0.207 mg QE/mg EO) compared to T. pallidus. The DPPH assay indicated that O. grossii EOs possessed approximately twice the antiradical activity of T. pallidus, with IC

Identifiants

pubmed: 37973884
doi: 10.1038/s41598-023-47215-4
pii: 10.1038/s41598-023-47215-4
pmc: PMC10654524
doi:

Substances chimiques

carvacrol 9B1J4V995Q
Oils, Volatile 0
4-cymene 1G1C8T1N7Q
gamma-terpinene 4YGF4PQP49
Thymol 3J50XA376E
Eucalyptol RV6J6604TK
Antioxidants 0
Anti-Bacterial Agents 0
Phytochemicals 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

20021

Informations de copyright

© 2023. The Author(s).

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Auteurs

Hind Zejli (H)

Laboratory of Engineering, Electrochemistry, Modeling and Environment, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, B. P. 1796, Fes-Atlas, Morocco. hind.zejli@usmba.ac.ma.

Aziza Fitat (A)

Laboratory of Engineering, Electrochemistry, Modeling and Environment, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, B. P. 1796, Fes-Atlas, Morocco.

Youssra Lefrioui (Y)

Laboratory of Biotechnology, Health, Agrofood and Environment, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, B. P. 1796, Fes-Atlas, Morocco.

Farhan Siddique (F)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan.

Mohammed Bourhia (M)

Department of Chemistry and Biochemistry, Faculty of Medicine and Pharmacy, Ibn Zohr University, 70000, Laayoune, Morocco.

Fatima Zahra Bousseraf (FZ)

Laboratory of Engineering, Electrochemistry, Modeling and Environment, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, B. P. 1796, Fes-Atlas, Morocco.

Ahmad Mohammad Salamatullah (AM)

Department of Food Science & Nutrition, College of Food and Agricultural Sciences, King Saud University, 11, P.O. Box 2460, Riyadh, 11451, Saudi Arabia.

Hiba-Allah Nafidi (HA)

Department of Food Science, Faculty of Agricultural and Food Sciences, Laval University, 2325, Quebec City, QC, G1V 0A6, Canada.

Amare Bitew Mekonnen (AB)

Department of Biology, Bahir Dar University, P. O. Box 79, Bahir Dar, Ethiopia. amarebitew@gmail.com.

Abdelkader Gourch (A)

Laboratory of Engineering, Electrochemistry, Modeling and Environment, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, B. P. 1796, Fes-Atlas, Morocco.

Mustapha Taleb (M)

Laboratory of Engineering, Electrochemistry, Modeling and Environment, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, B. P. 1796, Fes-Atlas, Morocco.

Abdelfattah Abdellaoui (A)

Laboratory of Engineering, Electrochemistry, Modeling and Environment, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, B. P. 1796, Fes-Atlas, Morocco.

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Classifications MeSH