Blood and tissue docosahexaenoic acid (DHA, 22:6n-3) turnover rates from Ahiflower® oil are not different than from DHA ethyl ester oil in a diet switch mouse model.
Ahiflower oil
Docosahexaenoic acid
Flaxseed oil
Half-life
Synthesis
Turnover
Journal
Biochimica et biophysica acta. Molecular and cell biology of lipids
ISSN: 1879-2618
Titre abrégé: Biochim Biophys Acta Mol Cell Biol Lipids
Pays: Netherlands
ID NLM: 101731727
Informations de publication
Date de publication:
Jan 2024
Jan 2024
Historique:
received:
09
08
2023
revised:
06
11
2023
accepted:
07
11
2023
medline:
5
12
2023
pubmed:
18
11
2023
entrez:
17
11
2023
Statut:
ppublish
Résumé
Ahiflower® oil is high in α-linolenic and stearidonic acids, however, tissue/blood docosahexaenoic acid (DHA, 22:6n-3) turnover from dietary Ahiflower oil has not been investigated. In this study, we use compound-specific isotope analysis to determine tissue DHA synthesis/turnover from Ahiflower, flaxseed and DHA oils. Pregnant BALB/c mice (13-17 days) were placed on a 2 % algal DHA oil diet of high carbon-13 content (δ
Identifiants
pubmed: 37977491
pii: S1388-1981(23)00146-4
doi: 10.1016/j.bbalip.2023.159422
pii:
doi:
Substances chimiques
Docosahexaenoic Acids
25167-62-8
Linseed Oil
8001-26-1
Fatty Acids, Omega-3
0
Fish Oils
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
159422Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest RPB has received research grants from Bunge Ltd., Arctic Nutrition, the Dairy Farmers of Canada and Nestle Inc., as well as travel support from Mead Johnson and mass spectrometry equipment and support from Sciex. In addition, RPB is on the executive board of the International Society for the Study of Fatty Acids and Lipids and held a meeting on behalf of Fatty Acids and Cell Signaling, both of which rely on corporate sponsorship. RPB has given expert testimony in relation to supplements and the brain. RPB also provides complimentary fatty acid analysis for farmers, food producers and others involved in the food industry, some of whom provide free food samples. GC is the Vice-President, Science & Regulatory at Natures Crops International, who funded this research and is the sole producer of Ahiflower oil world-wide. There are no other conflicts of interest.