Wildlife endogenous retroviruses: colonization, consequences, and cooption.
cooption
endogenous retrovirus
evolution
population
syncytin
wildlife
Journal
Trends in genetics : TIG
ISSN: 0168-9525
Titre abrégé: Trends Genet
Pays: England
ID NLM: 8507085
Informations de publication
Date de publication:
02 2024
02 2024
Historique:
received:
11
09
2023
revised:
24
10
2023
accepted:
31
10
2023
medline:
8
2
2024
pubmed:
21
11
2023
entrez:
20
11
2023
Statut:
ppublish
Résumé
Endogenous retroviruses (ERVs) are inherited genomic remains of past germline retroviral infections. Research on human ERVs has focused on medical implications of their dysregulation on various diseases. However, recent studies incorporating wildlife are yielding remarkable perspectives on long-term retrovirus-host interactions. These initial forays into broader taxonomic analysis, including sequencing of multiple individuals per species, show the incredible plasticity and variation of ERVs within and among wildlife species. This demonstrates that stochastic processes govern much of the vertebrate genome. In this review, we elaborate on discoveries pertaining to wildlife ERV origins and evolution, genome colonization, and consequences for host biology.
Identifiants
pubmed: 37985317
pii: S0168-9525(23)00253-6
doi: 10.1016/j.tig.2023.10.014
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
149-159Subventions
Organisme : Swedish Research Council
ID : 2021-01740
Organisme : Deutsche Forschungsgemeinschaft (DFG).
ID : GR 3924/15-1 AND GR 3924/12-1
Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of interests No interests are declared.