Cardiometabolic risk factors in South American children: A systematic review and meta-analysis.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2023
2023
Historique:
received:
28
07
2022
accepted:
20
10
2023
medline:
27
11
2023
pubmed:
22
11
2023
entrez:
22
11
2023
Statut:
epublish
Résumé
Cardiometabolic risk factors (impaired fasting glucose, abdominal obesity, high blood pressure, dyslipidemia) cluster in children, may predict adult disease burden, and are inadequately characterized in South American children. To quantify the burden of cardiometabolic risk factors in South American children (0-21 years) and identify knowledge gaps. We systematically searched PubMed, Google Scholar, and the Latin American and Caribbean Health Sciences Literature via Virtual Health Library from 2000-2021 in any language. Two independent reviewers screened and extracted all data. 179 studies of 2,181 screened were included representing 10 countries (n = 2,975,261). 12.2% of South American children experienced obesity, 21.9% elevated waist circumference, 3.0% elevated fasting glucose, 18.1% high triglycerides, 29.6% low HDL cholesterol, and 8.6% high blood pressure. Cardiometabolic risk factor definitions varied widely. Chile exhibited the highest prevalence of obesity/overweight, low HDL, and impaired fasting glucose. Ecuador exhibited the highest prevalence of elevated blood pressure. Rural setting (vs. urban or mixed) and indigenous origin protected against most cardiometabolic risk factors. South American children experience high rates of obesity, overweight, and dyslipidemia. International consensus on cardiometabolic risk factor definitions for children will lead to improved diagnosis of cardiometabolic risk factors in this population, and future research should ensure inclusion of unreported countries and increased representation of indigenous populations.
Sections du résumé
BACKGROUND
BACKGROUND
Cardiometabolic risk factors (impaired fasting glucose, abdominal obesity, high blood pressure, dyslipidemia) cluster in children, may predict adult disease burden, and are inadequately characterized in South American children.
OBJECTIVES
OBJECTIVE
To quantify the burden of cardiometabolic risk factors in South American children (0-21 years) and identify knowledge gaps.
METHODS
METHODS
We systematically searched PubMed, Google Scholar, and the Latin American and Caribbean Health Sciences Literature via Virtual Health Library from 2000-2021 in any language. Two independent reviewers screened and extracted all data.
RESULTS
RESULTS
179 studies of 2,181 screened were included representing 10 countries (n = 2,975,261). 12.2% of South American children experienced obesity, 21.9% elevated waist circumference, 3.0% elevated fasting glucose, 18.1% high triglycerides, 29.6% low HDL cholesterol, and 8.6% high blood pressure. Cardiometabolic risk factor definitions varied widely. Chile exhibited the highest prevalence of obesity/overweight, low HDL, and impaired fasting glucose. Ecuador exhibited the highest prevalence of elevated blood pressure. Rural setting (vs. urban or mixed) and indigenous origin protected against most cardiometabolic risk factors.
CONCLUSIONS
CONCLUSIONS
South American children experience high rates of obesity, overweight, and dyslipidemia. International consensus on cardiometabolic risk factor definitions for children will lead to improved diagnosis of cardiometabolic risk factors in this population, and future research should ensure inclusion of unreported countries and increased representation of indigenous populations.
Identifiants
pubmed: 37992076
doi: 10.1371/journal.pone.0293865
pii: PONE-D-22-19334
pmc: PMC10664905
doi:
Substances chimiques
Blood Glucose
0
Types de publication
Meta-Analysis
Systematic Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0293865Informations de copyright
Copyright: © 2023 Singleton et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Déclaration de conflit d'intérêts
The authors declare that no competing interests exist.
Références
Nutr Hosp. 2017 Oct 24;34(5):1044-1049
pubmed: 29130700
Pediatrics. 2007 Aug;120(2):340-5
pubmed: 17671060
Int J Behav Nutr Phys Act. 2007 Sep 19;4:41
pubmed: 17880726
Diabetol Metab Syndr. 2010 Jun 09;2(1):39
pubmed: 20529375
Rev Salud Publica (Bogota). 2008 Nov-Dec;10(5):788-95
pubmed: 19360227
Obes Rev. 2001 May;2(2):99-106
pubmed: 12119667
Cad Saude Publica. 2012 Jun;28(6):1175-82
pubmed: 22666821
Nutr Hosp. 2019 Mar 07;36(1):13-19
pubmed: 30816790
Child Obes. 2016 Feb;12(1):12-9
pubmed: 26785314
BMC Pediatr. 2020 Apr 28;20(1):188
pubmed: 32345250
J Clin Endocrinol Metab. 2014 Mar;99(3):1044-52
pubmed: 24423351
Nutr J. 2013 Jan 30;12:19
pubmed: 23363783
Int J Dent Hyg. 2017 Nov;15(4):e156-e162
pubmed: 27699998
Endocrinol Nutr. 2012 May;59(5):296-303
pubmed: 22521300
Arq Bras Cardiol. 2020 Jan;114(1):47-56
pubmed: 31644697
Nutr Hosp. 2019 Mar 07;36(1):96-102
pubmed: 30834755
Life Sci. 2013 Jul 30;93(2-3):64-8
pubmed: 23743170
Nutrition. 2019 Apr;60:170-174
pubmed: 30611079
Nutrition. 2016 Apr;32(4):426-31
pubmed: 26743976
J Epidemiol Community Health. 2015 Jun;69(6):580-7
pubmed: 25691273
Cardiovasc Hematol Agents Med Chem. 2014;12(1):42-9
pubmed: 24845422
PLoS One. 2014 Apr 08;9(4):e93150
pubmed: 24714401
J Obes. 2014;2014:618293
pubmed: 24872892
Nutrition. 2020 Sep;77:110786
pubmed: 32283342
Food Nutr Bull. 2013 Dec;34(4):388-401
pubmed: 24605689
Nutr Hosp. 2015 Dec 01;32(6):2576-83
pubmed: 26667706
Nutr Metab Cardiovasc Dis. 2011 Jan;21(1):33-8
pubmed: 19857944
Cardiovasc Hematol Agents Med Chem. 2015;13(2):129-36
pubmed: 26652712
Arch Latinoam Nutr. 2009 Mar;59(1):30-7
pubmed: 19480341
Rev Med Chil. 2010 Nov;138(11):1365-72
pubmed: 21279248
Cad Saude Publica. 2018 Sep 06;34(9):e00105317
pubmed: 30208174
J Cardiometab Syndr. 2009 Winter;4(1):50-6
pubmed: 19245517
Pediatr Obes. 2017 Feb;12(1):85-92
pubmed: 27005443
Nutr Hosp. 2012 Jul-Aug;27(4):1228-35
pubmed: 23165566
BMC Public Health. 2007 Sep 07;7:235
pubmed: 17822567
Invest Clin. 2015 Dec;56(4):389-405
pubmed: 29938968
Cad Saude Publica. 2004 Nov-Dec;20(6):1627-32
pubmed: 15608865
Am J Clin Nutr. 2013 Feb;97(2):318-25
pubmed: 23283497
Cad Saude Publica. 2018 Feb 05;34(1):e00175016
pubmed: 29412322
Rev Peru Med Exp Salud Publica. 2011 Jun;28(2):222-7
pubmed: 21845301
Acta Cient Venez. 2003;54(4):254-62
pubmed: 15916180
Arq Bras Cardiol. 2009 Sep;93(3):253-60
pubmed: 19851653
Cad Saude Publica. 2013 Apr;29(4):793-800
pubmed: 23568308
Arq Bras Cardiol. 2009 Aug;93(2):147-53
pubmed: 19838492
BMC Pediatr. 2014 Apr 18;14:106
pubmed: 24745348
Eur J Public Health. 2012 Jun;22(3):383-9
pubmed: 21616992
Adv Obes Weight Manag Control. 2020;10(5):146-161
pubmed: 33305001
Biomed Environ Sci. 2016 Nov;29(11):834-839
pubmed: 27998391
Int J Obes (Lond). 2016 Jan;40(1):147-52
pubmed: 26264757
J Phys Act Health. 2015 May;12(5):604-9
pubmed: 24905896
Public Health Nutr. 2016 Feb;19(3):486-93
pubmed: 25990645
Clinics (Sao Paulo). 2018 Nov 29;73:e438
pubmed: 30517282
Am J Clin Nutr. 2010 Jan;91(1):166-74
pubmed: 19923378
Public Health Nutr. 2012 Jun;15(6):1056-64
pubmed: 22030258
Rev Med Chil. 2009 Jan;137(1):39-45
pubmed: 19399320
Diabetes Technol Ther. 2016 Apr;18(4):233-9
pubmed: 27028794
Public Health Nutr. 2019 Jan;22(1):140-146
pubmed: 30295220
Br J Nutr. 2014 Dec 14;112(11):1905-10
pubmed: 25296155
J Pediatr. 2008 Feb;152(2):160-4
pubmed: 18206681
Transl Pediatr. 2019 Dec;8(5):363-370
pubmed: 31993348
Rev Peru Med Exp Salud Publica. 2016 Oct-Dec;33(4):640-650
pubmed: 28327832
J Pediatr. 2006 Feb;148(2):149-51
pubmed: 16492419
Diabetol Metab Syndr. 2017 Apr 19;9:24
pubmed: 28435445
Circulation. 2004 Oct 19;110(16):2494-7
pubmed: 15477412
Diabetes Metab Syndr. 2017 Nov;11 Suppl 1:S397-S401
pubmed: 28284912
Rev Paul Pediatr. 2013 Dec;31(4):437-43
pubmed: 24473947
Nutr Hosp. 2018 Jan 10;35(1):44-49
pubmed: 29565148
Rev Med Chil. 2018 Sep;146(9):978-986
pubmed: 30725017
Public Health Nutr. 2012 Nov;15(11):2086-90
pubmed: 22444072
Rev Chil Pediatr. 2015 May-Jun;86(3):182-8
pubmed: 26363859
Pediatrics. 2017 Aug;140(2):
pubmed: 28739653
J Pediatr (Rio J). 2014 May-Jun;90(3):258-66
pubmed: 24184269
Biomedica. 2007 Sep;27(3):385-99
pubmed: 18320104
Obesity (Silver Spring). 2009 Aug;17(8):1603-8
pubmed: 19265798
Arch Argent Pediatr. 2014 Dec;112(6):557-61
pubmed: 25362907
Cien Saude Colet. 2019 Oct 28;24(11):4019-4030
pubmed: 31664375
Rev Peru Med Exp Salud Publica. 2013 Oct-Dec;30(4):583-9
pubmed: 24448933
Pediatr Diabetes. 2011 May;12(3 Pt 2):229-34
pubmed: 21518411
Arch Argent Pediatr. 2014 Dec;112(6):511-8
pubmed: 25362909
Rev Peru Med Exp Salud Publica. 2013 Jul;30(3):399-407
pubmed: 24100813
Nutrition. 2018 Oct;54:105-110
pubmed: 29778907
J Trop Pediatr. 2013 Feb;59(1):54-8
pubmed: 22946122
Rev Med Chil. 2011 Nov;139(11):1435-43
pubmed: 22446648
Pediatr Diabetes. 2013 May;14(3):203-10
pubmed: 23331968
Endocrinol Nutr. 2016 Feb;63(2):58-63
pubmed: 26718194
Public Health Nutr. 2007 Sep;10(9):878-82
pubmed: 17381936
Public Health Nutr. 2009 Sep;12(9):1451-61
pubmed: 19102808
J Obes. 2019 Aug 1;2019:2631713
pubmed: 31467705
Lancet Glob Health. 2020 Jan;8(1):e123-e133
pubmed: 31839128
Clin Biochem. 2013 Dec;46(18):1837-41
pubmed: 24012695
Clin Biochem. 2010 Mar;43(4-5):435-41
pubmed: 19913002
J Nutr. 2018 Apr 1;148(4):632-642
pubmed: 29659966
Matern Child Nutr. 2012 Apr;8(2):267-74
pubmed: 22405702
Cad Saude Publica. 2016 Feb;32(2):e00181514
pubmed: 26958824
Environ Res. 2019 Aug;175:335-342
pubmed: 31150932
Diabetes Metab Syndr. 2016 Jan-Mar;10(1 Suppl 1):S103-9
pubmed: 26867955
Arch Endocrinol Metab. 2020 Aug;64(4):445-453
pubmed: 32267366
Arq Bras Endocrinol Metabol. 2006 Feb;50(1):60-7
pubmed: 16628276
Ital J Pediatr. 2016 Nov 15;42(1):97
pubmed: 27846912
Public Health Nutr. 2018 Aug;21(11):2004-2012
pubmed: 29478422
Am J Hum Biol. 2019 May;31(3):e23224
pubmed: 30779467
Rev Salud Publica (Bogota). 2018 Mar-Apr;20(2):171-176
pubmed: 30569997
Nutr Hosp. 2017 Nov 16;34(5):1338-1344
pubmed: 29280649
Arch Argent Pediatr. 2010 Feb;108(1):68-70
pubmed: 20204242
J Pediatr. 2017 Sep;188:57-63
pubmed: 28651798
BMC Public Health. 2018 Mar 14;18(1):353
pubmed: 29540170
Nutr Metab Cardiovasc Dis. 2012 Mar;22(3):244-51
pubmed: 20705440
Pediatr Clin North Am. 2009 Dec;56(6):1285-302
pubmed: 19962022
J Health Popul Nutr. 2015 Mar;33(1):85-91
pubmed: 25995725
Int J Pediatr Adolesc Med. 2017 Dec;4(4):133-137
pubmed: 30805517
Pediatr Cardiol. 2009 Apr;30(3):248-55
pubmed: 19020793
Diabetes Metab Syndr Obes. 2020 May 21;13:1733-1741
pubmed: 32547135
Am J Public Health. 2016 Jul;106(7):1301-7
pubmed: 27196644
Worldviews Evid Based Nurs. 2004;1(3):176-84
pubmed: 17163895
BMC Genet. 2016 Jun 27;17(1):93
pubmed: 27350247
Public Health Nutr. 2011 Jul;14(7):1270-8
pubmed: 21486522
Br J Nutr. 2019 Jan;121(1):93-99
pubmed: 30311592
Rev Paul Pediatr. 2019 Apr-Jun;37(2):181-187
pubmed: 30810693
Am J Hum Biol. 2007 Jan-Feb;19(1):61-73
pubmed: 17160975
Am J Hum Biol. 2020 Nov;32(6):e23424
pubmed: 32320119
J Pediatr. 2009 Jan;154(1):101-5
pubmed: 18692202
Invest Clin. 2016 Jun;57(2):143-157
pubmed: 28429895
Pediatr Diabetes. 2006 Aug;7(4):201-4
pubmed: 16911006
Nutr Hosp. 2014 Sep 01;30(3):526-34
pubmed: 25238827
BMC Public Health. 2011 Jul 22;11:585
pubmed: 21781313
World J Pediatr. 2016 Nov;12(4):477-483
pubmed: 26830308
Arch Pediatr Adolesc Med. 2003 Aug;157(8):821-7
pubmed: 12912790
J Nutr Sci Vitaminol (Tokyo). 2016;62(2):73-80
pubmed: 27264090
Medicine (Baltimore). 2019 May;98(19):e15666
pubmed: 31083270
Int J Paediatr Dent. 2017 Nov;27(6):532-539
pubmed: 28222484
J Pediatr (Rio J). 2018 Mar - Apr;94(2):177-183
pubmed: 28843060
Rev Paul Pediatr. 2021;39:e2019088
pubmed: 32876314
Lancet. 2017 Dec 16;390(10113):2627-2642
pubmed: 29029897
Pediatr Diabetes. 2007 Oct;8(5):299-306
pubmed: 17850473
J Pediatr (Rio J). 2009 Jan-Feb;85(1):67-71
pubmed: 19198735
Rev Paul Pediatr. 2015 Jan-Mar;33(1):42-9
pubmed: 25662562
Arch Endocrinol Metab. 2016 Feb 16;60(3):205-10
pubmed: 26886094
Rev Med Chil. 2007 Jan;135(1):63-70
pubmed: 17369985
Am J Hum Biol. 2013 Jul-Aug;25(4):524-33
pubmed: 23657874
Clin Biochem. 2012 Oct;45(15):1161-6
pubmed: 22562083
Public Health Nutr. 2013 Feb;16(2):228-32
pubmed: 22877412