Sequential appetite suppression by oral and visceral feedback to the brainstem.

Feedback Appetite Appetite Regulation / physiology Brain Stem / physiology Satiation / physiology Eating / physiology

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 23 10 2022
accepted: 17 10 2023
medline: 11 12 2023
pubmed: 23 11 2023
entrez: 22 11 2023
Statut: ppublish

Résumé

The termination of a meal is controlled by dedicated neural circuits in the caudal brainstem. A key challenge is to understand how these circuits transform the sensory signals generated during feeding into dynamic control of behaviour. The caudal nucleus of the solitary tract (cNTS) is the first site in the brain where many meal-related signals are sensed and integrated

Identifiants

DOI: 10.1038/s41586-023-06758-2 PMID: 37993711 PMC: PMC10700140
pubmed: 37993711
doi: 10.1038/s41586-023-06758-2
pii: 10.1038/s41586-023-06758-2
pmc: PMC10700140
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

130-137

Subventions

Organisme : NIDDK NIH HHS
ID : F31 DK137586
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK106399
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS116626
Pays : United States

Informations de copyright

© 2023. The Author(s).

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Auteurs

Truong Ly (T)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA.
Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA.

Jun Y Oh (JY)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Nilla Sivakumar (N)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA.
Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA.

Sarah Shehata (S)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Naymalis La Santa Medina (N)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Heidi Huang (H)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Zhengya Liu (Z)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA.
Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA.
ORCID: 0009-0001-2352-3141

Wendy Fang (W)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Chris Barnes (C)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Naz Dundar (N)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA.
Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA.

Brooke C Jarvie (BC)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA.

Anagh Ravi (A)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA.
Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA.

Olivia K Barnhill (OK)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA.
Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA.

Chelsea Li (C)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Grace R Lee (GR)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Jaewon Choi (J)

Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.

Heeun Jang (H)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.

Zachary A Knight (ZA)

Department of Physiology, University of California, San Francisco, San Francisco, CA, USA. zachary.knight@ucsf.edu.
Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA. zachary.knight@ucsf.edu.
Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA, USA. zachary.knight@ucsf.edu.
Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA. zachary.knight@ucsf.edu.
ORCID: 0000-0001-7621-1478

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Analyse des systèmes › Recherche opérationnelle › Rétroaction › Sequential appetite suppression by oral and...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil buccodentaire et de l'appareil digestif › Phénomènes physiologiques de l'appareil digestif › Faim › Appétit › Sequential appetite suppression by oral and...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil buccodentaire et de l'appareil digestif › Phénomènes physiologiques de l'appareil digestif › Faim › Appétit › Régulation de l'appétit › Sequential appetite suppression by oral and...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Tronc cérébral › Sequential appetite suppression by oral and...
questionsmedicales.fr › Phénomènes psychologiques › Satiété › Sequential appetite suppression by oral and...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil buccodentaire et de l'appareil digestif › Phénomènes physiologiques de l'appareil digestif › Consommation alimentaire › Sequential appetite suppression by oral and...