Quercetin-1,2,3-Triazole Hybrids as Multifunctional Anti-Alzheimer's Agents.
1,2,3-triazole
Alzheimer’s diseases
ROS protection
antioxidant assay
cholinesterase inhibitory assays
hybrids
quercetin
toxicity
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
09 Nov 2023
09 Nov 2023
Historique:
received:
09
10
2023
revised:
03
11
2023
accepted:
06
11
2023
medline:
27
11
2023
pubmed:
25
11
2023
entrez:
25
11
2023
Statut:
epublish
Résumé
The number of patients with Alzheimer's disease (AD) continues to rise and, despite the efforts of researchers, there are still no effective treatments for this multifaceted disease. The main objective of this work was the search for multifunctional and more effective anti-Alzheimer agents. Herein, we report the evaluation of a library of quercetin-1,2,3-triazole hybrids (
Identifiants
pubmed: 38005217
pii: molecules28227495
doi: 10.3390/molecules28227495
pmc: PMC10673615
pii:
doi:
Substances chimiques
Cholinesterase Inhibitors
0
Quercetin
9IKM0I5T1E
Hydrogen Peroxide
BBX060AN9V
Galantamine
0D3Q044KCA
Acetylcholinesterase
EC 3.1.1.7
Neuroprotective Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Fundação para a Ciência e Tecnologia
ID : LAQV-REQUIMTE (FCT/ MCTES; UIDB/50006/2020|UIDP/50006/2020)
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