Real-world treatment outcome of direct-acting antivirals and patient survival rates in chronic hepatitis C virus infection in Eritrea.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
27 Nov 2023
Historique:
received: 02 07 2022
accepted: 10 11 2023
medline: 29 11 2023
pubmed: 28 11 2023
entrez: 27 11 2023
Statut: epublish

Résumé

Reliable real-world data on direct acting anti-retroviral (DAA) uptake and treatment outcomes are lacking for patients with hepatitis C virus (HCV) in sub-Saharan Africa. This study provides data on HCV DAA-based treatment outcomes, mortality, loss-to-follow up, and associated factors among patients in Eritrea. A multicenter retrospective observational cohort study was conducted in two tertiary hospitals in Asmara, Eritrea. A structured checklist was used to collect data from patient's cards. Descriptive and inferential statistics used included means (± Standard deviation (SD), medians (Interquartile range (IQR), chi-squire (χ

Identifiants

pubmed: 38012181
doi: 10.1038/s41598-023-47258-7
pii: 10.1038/s41598-023-47258-7
pmc: PMC10682448
doi:

Substances chimiques

Antiviral Agents 0

Types de publication

Observational Study Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20792

Informations de copyright

© 2023. The Author(s).

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Auteurs

Ghirmay Ghebrekidan Ghebremeskel (GG)

Nakfa Hospital, Northern Red Sea Ministry of Health Branch, Nakfa, Eritrea. GhirmayGGG@gmail.com.

Michael Berhe Solomon (M)

National Health Observatory Unit, Ministry of Health, Asmara, Eritrea.

Oliver Okoth Achila (OO)

Unit of Clinical Laboratory Science, Orotta College of Medicine and Health Sciences (OCMHS), Asmara, Eritrea.

Samuel Tekle Mengistu (ST)

Nakfa Hospital, Northern Red Sea Ministry of Health Branch, Nakfa, Eritrea.

Rahel Frezghi Asmelash (RF)

Hamelmalo Community Hospital, Anseba Zone Ministry of Health Branch, Hamelmalo, Eritrea.

Araia Berhane Mesfin (A)

National Communicable Disease Control Division, Ministry of Health, Asmara, Eritrea.

Mohammed Elfatih Hamida (ME)

Department of Medical Microbiology, Orotta College of Medicine and Health Sciences (OCMHS), Asmara, Eritrea.

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Classifications MeSH