Massive intein content in

evolution genomics inteins microbiology mobile genetic elements

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
05 Dec 2023
Historique:
pmc-release: 29 05 2024
medline: 1 12 2023
pubmed: 29 11 2023
entrez: 29 11 2023
Statut: ppublish

Résumé

Inteins are self-splicing protein elements found in viruses and all three domains of life. How the DNA encoding these selfish elements spreads within and between genomes is poorly understood, particularly in eukaryotes where inteins are scarce. Here, we show that the nuclear genomes of three strains of

Identifiants

pubmed: 38019867
doi: 10.1073/pnas.2306381120
pmc: PMC10710043
doi:

Substances chimiques

Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2306381120

Subventions

Organisme : Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC)
ID : RGPIN-2019-05058
Organisme : Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC)
ID : RGPIN-2022-05430
Organisme : CAS | Institute of Botany of the Czech Academy of Sciences (Institute of Botany of the ASCR)
ID : 21-30563S
Organisme : Vetenskapsrådet (VR)
ID : 2020-05071

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

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Auteurs

Lucie Gallot-Lavallée (L)

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.

Jon Jerlström-Hultqvist (J)

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
Microbiology and Immunology, Department of Cell and Molecular Biology, Biomedical Centre, Uppsala University, Uppsala 751 24, Sweden.

Paula Zegarra-Vidarte (P)

Microbiology and Immunology, Department of Cell and Molecular Biology, Biomedical Centre, Uppsala University, Uppsala 751 24, Sweden.

Dayana E Salas-Leiva (DE)

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.

Courtney W Stairs (CW)

Microbiology Group, Department of Biology, Lund University, Lund 223 62, Sweden.

Ivan Čepička (I)

Department of Zoology, Charles University, Prague 128 00, Czech Republic.

Andrew J Roger (AJ)

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.

John M Archibald (JM)

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.

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Classifications MeSH