Textbook outcome in distal pancreatectomy: A multicenter study.


Journal

Surgery
ISSN: 1532-7361
Titre abrégé: Surgery
Pays: United States
ID NLM: 0417347

Informations de publication

Date de publication:
Apr 2024
Historique:
received: 12 04 2023
revised: 01 11 2023
accepted: 11 11 2023
medline: 18 3 2024
pubmed: 10 12 2023
entrez: 9 12 2023
Statut: ppublish

Résumé

Textbook outcome is an interesting quality metrics tool. Information on textbook outcomes in distal pancreatectomy is very scarce. In this study we determined textbook outcome in a distal pancreatectomy multicenter database and propose a specific definition of textbook outcome-distal pancreatectomy that includes pancreatic fistula. Retrospective multicenter observational study of distal pancreatectomy performed at 8 hepatopancreatobiliary surgery units from January 1, 2008, to December 31, 2018. The inclusion criteria were any scheduled distal pancreatectomy performed for any diagnosis and age > 18 years. Specific textbook outcome-distal pancreatectomy was defined as hospital stay P < 75, no Clavien-Dindo complications (≥ III), no hospital mortality, and no readmission recorded at 90 days, and the absence of pancreatic fistula (B/C). Of the 450 patients included, 262 (58.2%) obtained textbook outcomes. Prolonged stay was the parameter most frequently associated with failure to achieve textbook outcomes. The textbook outcome group presented the following results. Preoperative: lower American Society of Anesthesiologists score < III, a lower percentage of smokers, and less frequent tumor invasion of neighboring organs or vascular invasion; operative: major laparoscopic approach, and less resection of neighboring organs and less operative transfusion; postoperative: lower percentage of delayed gastric emptying and pancreatic fistula B/C, and diagnosis other an adenocarcinoma. In the multivariate study, the American Society of Anesthesiologists score > II, resection of neighboring organs, B/C pancreatic fistula, and delayed gastric emptying were associated with failure to achieve textbook outcomes. The textbook outcome rate in our 450 pancreaticoduodenectomies was 58.2%. In the multivariate analysis, the causes of failure to achieve textbook outcomes were American Society of Anesthesiologists score > II, resection of neighboring organs, pancreatic fistula B/C, and delayed gastric emptying. We believe that pancreatic fistula should be added to the specific definition of textbook outcome-distal pancreatectomy because it is the most frequent complication of this procedure.

Sections du résumé

BACKGROUND BACKGROUND
Textbook outcome is an interesting quality metrics tool. Information on textbook outcomes in distal pancreatectomy is very scarce. In this study we determined textbook outcome in a distal pancreatectomy multicenter database and propose a specific definition of textbook outcome-distal pancreatectomy that includes pancreatic fistula.
METHODS METHODS
Retrospective multicenter observational study of distal pancreatectomy performed at 8 hepatopancreatobiliary surgery units from January 1, 2008, to December 31, 2018. The inclusion criteria were any scheduled distal pancreatectomy performed for any diagnosis and age > 18 years. Specific textbook outcome-distal pancreatectomy was defined as hospital stay P < 75, no Clavien-Dindo complications (≥ III), no hospital mortality, and no readmission recorded at 90 days, and the absence of pancreatic fistula (B/C).
RESULTS RESULTS
Of the 450 patients included, 262 (58.2%) obtained textbook outcomes. Prolonged stay was the parameter most frequently associated with failure to achieve textbook outcomes. The textbook outcome group presented the following results. Preoperative: lower American Society of Anesthesiologists score < III, a lower percentage of smokers, and less frequent tumor invasion of neighboring organs or vascular invasion; operative: major laparoscopic approach, and less resection of neighboring organs and less operative transfusion; postoperative: lower percentage of delayed gastric emptying and pancreatic fistula B/C, and diagnosis other an adenocarcinoma. In the multivariate study, the American Society of Anesthesiologists score > II, resection of neighboring organs, B/C pancreatic fistula, and delayed gastric emptying were associated with failure to achieve textbook outcomes.
CONCLUSION CONCLUSIONS
The textbook outcome rate in our 450 pancreaticoduodenectomies was 58.2%. In the multivariate analysis, the causes of failure to achieve textbook outcomes were American Society of Anesthesiologists score > II, resection of neighboring organs, pancreatic fistula B/C, and delayed gastric emptying. We believe that pancreatic fistula should be added to the specific definition of textbook outcome-distal pancreatectomy because it is the most frequent complication of this procedure.

Identifiants

pubmed: 38071134
pii: S0039-6060(23)00867-X
doi: 10.1016/j.surg.2023.11.012
pii:
doi:

Types de publication

Multicenter Study Observational Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1134-1139

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Celia Villodre (C)

Department of Surgery, Hospital General Universitario Dr. Balmis, Alicante, Spain; ISABIAL: Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain; Universidad Miguel Hernández, Alicante, Spain.

Juan Del Río-Martín (J)

Department of Surgery, Hospital Auxilio Mutuo, San Juan, Puerto Rico.

Gerardo Blanco-Fernández (G)

Department of Surgery, Complejo Hospitalario de Badajoz, Spain.

Miguel Cantalejo-Díaz (M)

Department of Surgery, Hospital Universitario Miguel Servet, Zaragoza, Spain.

Fernando Pardo (F)

Department of Surgery, Clínica Universidad de Navarra, Pamplona, Spain.

Silvia Carbonell (S)

Department of Surgery, Hospital General Universitario Dr. Balmis, Alicante, Spain; ISABIAL: Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain.

Elena Muñoz-Forner (E)

Department of Surgery, Hospital Clínico Univertario, University of Valencia, Biomedical Research Institute, Valencia, Spain.

Alberto Carabias (A)

Hospital Universitario de Getafe, Getafe, Spain.

Alba Manuel-Vazquez (A)

Hospital Universitario de Getafe, Getafe, Spain.

Pedro J Hernández-Rivera (PJ)

University of Puerto Rico School of Medicine, Department of Surgery.

Isabel Jaén-Torrejimeno (I)

Department of Surgery, Complejo Hospitalario de Badajoz, Spain.

Helga K Kälviäinen-Mejia (HK)

Department of Surgery, Hospital Universitario Miguel Servet, Zaragoza, Spain.

Fernando Rotellar (F)

Department of Surgery, Clínica Universidad de Navarra, Pamplona, Spain.

Marina Garcés-Albir (M)

Department of Surgery, Hospital Clínico Univertario, University of Valencia, Biomedical Research Institute, Valencia, Spain.

Raquel Latorre (R)

Hospital Universitario de Guadalajara, Guadalajara, Spain.

Texell Longoria-Dubocq (T)

University of Puerto Rico School of Medicine, Department of Surgery.

Noelia De Armas-Conde (N)

Department of Surgery, Complejo Hospitalario de Badajoz, Spain.

Alejandro Serrablo (A)

Department of Surgery, Hospital Universitario Miguel Servet, Zaragoza, Spain.

Sara Esteban Gordillo (S)

Department of Surgery, Clínica Universidad de Navarra, Pamplona, Spain.

Luis Sabater (L)

Department of Surgery, Hospital Clínico Univertario, University of Valencia, Biomedical Research Institute, Valencia, Spain.

Mario Serradilla-Martín (M)

Instituto de Investigación Sanitaria Aragón, Department of Surgery, Hospital Universitario Miguel Servet, Zaragoza, Spain. Electronic address: marioserradilla@hotmail.com.

José M Ramia (JM)

Department of Surgery, Hospital General Universitario Dr. Balmis, Alicante, Spain; ISABIAL: Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain; Universidad Miguel Hernández, Alicante, Spain.

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