Host response signature trends in persistent bacteraemia and metastatic infection due to

Humans Staphylococcal Infections / diagnosis Staphylococcus aureus Bacteremia / diagnosis Prospective Studies Gram-Negative Bacteria
Bloodstream infection biomarkers blood culture clinical score host response

Journal

Infectious diseases (London, England)
ISSN: 2374-4243
Titre abrégé: Infect Dis (Lond)
Pays: England
ID NLM: 101650235

Informations de publication

Date de publication:
Apr 2024
Historique:
medline: 18 3 2024
pubmed: 14 12 2023
entrez: 14 12 2023
Statut: ppublish

Résumé

A prompt diagnosis of bacteraemia and sepsis is essential. Markers to predict the risk of persistent bacteraemia and metastatic infection are lacking. SeptiCyte RAPID is a host response assay stratifying patients according to the risk of infectious vs sterile inflammation through a scoring system (SeptiScore). In this study we explore the association between SeptiScore and persistent bacteraemia as well as metastatic and persistent infection in the context of a proven bacteraemia episode. This is a prospective multicentre observational 14-month study on patients with proven bacteraemia caused by We included 86 patients in the study, 40 with SeptiScores differ in the follow-up of

Sections du résumé

BACKGROUND UNASSIGNED
A prompt diagnosis of bacteraemia and sepsis is essential. Markers to predict the risk of persistent bacteraemia and metastatic infection are lacking. SeptiCyte RAPID is a host response assay stratifying patients according to the risk of infectious vs sterile inflammation through a scoring system (SeptiScore). In this study we explore the association between SeptiScore and persistent bacteraemia as well as metastatic and persistent infection in the context of a proven bacteraemia episode.
METHODS UNASSIGNED
This is a prospective multicentre observational 14-month study on patients with proven bacteraemia caused by
RESULTS UNASSIGNED
We included 86 patients in the study, 40 with
CONCLUSIONS UNASSIGNED
SeptiScores differ in the follow-up of

Identifiants

DOI: 10.1080/23744235.2023.2294122 PMID: 38093600
pubmed: 38093600
doi: 10.1080/23744235.2023.2294122
doi:

Types de publication

Observational Study Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

268-276

Auteurs

Anna Maria Peri (AM)

The University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.

Nastaran Rafiei (N)

Infectious Diseases Unit, Caboolture Hospital, Caboolture, Queensland, Australia.

Kevin O'Callaghan (K)

Infectious Diseases Unit, Redcliffe Hospital, Redcliffe, Queensland, Australia.

Anna Brischetto (A)

Infectious Diseases Unit, Redcliffe Hospital, Redcliffe, Queensland, Australia.

Bianca Graves (B)

Herston Infectious Diseases Institute, Herston, Brisbane, Queensland, Australia.

Holly Sinclair (H)

Infectious Diseases Unit, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

Matthew Eustace (M)

Infectious Diseases Unit, Redcliffe Hospital, Redcliffe, Queensland, Australia.

Karen Lim (K)

Infectious Diseases Unit, Redcliffe Hospital, Redcliffe, Queensland, Australia.

Jill Parkes-Smith (J)

Infectious Diseases Unit, Redcliffe Hospital, Redcliffe, Queensland, Australia.

Adam Stewart (A)

The University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Central Microbiology, Pathology Queensland, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

Natalie Davidson (N)

Infectious Diseases Unit, Redcliffe Hospital, Redcliffe, Queensland, Australia.

Alexis Tabah (A)

Intensive Care Unit, Redcliffe Hospital, Redcliffe, Queensland, Australia.
Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.
Queensland University of Technology (QUT), Brisbane, Queensland, Australia.

Haakon Bergh (H)

Central Microbiology, Pathology Queensland, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

Mark D Chatfield (MD)

The University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.

Patrick N A Harris (PNA)

The University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Herston Infectious Diseases Institute, Herston, Brisbane, Queensland, Australia.
Central Microbiology, Pathology Queensland, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

David L Paterson (DL)

The University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia.
Infectious Diseases Unit, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
ADVANCE-ID, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Infectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Host response signature trends in persistent...
questionsmedicales.fr › Infection › Infections bactériennes et mycoses › Infections bactériennes › Infections bactériennes à Gram positif › Infections à staphylocoques › Host response signature trends in persistent...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Host response signature trends in persistent...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Sepsie › Bactériémie › Host response signature trends in persistent...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Host response signature trends in persistent...
questionsmedicales.fr › Bactéries › Bactéries à Gram négatif › Host response signature trends in persistent...