Mechanisms of SARS-CoV-2 Inactivation Using UVC Laser Radiation.


Journal

ACS photonics
ISSN: 2330-4022
Titre abrégé: ACS Photonics
Pays: United States
ID NLM: 101634366

Informations de publication

Date de publication:
17 Jan 2024
Historique:
received: 15 06 2023
revised: 03 11 2023
accepted: 03 11 2023
medline: 22 1 2024
pubmed: 22 1 2024
entrez: 22 1 2024
Statut: epublish

Résumé

Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has had a tremendous impact on humanity. Prevention of transmission by disinfection of surfaces and aerosols through a chemical-free method is highly desirable. Ultraviolet C (UVC) light is uniquely positioned to achieve inactivation of pathogens. We report the inactivation of SARS-CoV-2 virus by UVC radiation and explore its mechanisms. A dose of 50 mJ/cm

Identifiants

pubmed: 38249683
doi: 10.1021/acsphotonics.3c00828
pmc: PMC10797618
doi:

Types de publication

Journal Article

Langues

eng

Pagination

42-52

Informations de copyright

© 2023 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

Auteurs

George Devitt (G)

School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Institute for Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Peter B Johnson (PB)

School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Institute for Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Niall Hanrahan (N)

School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Institute for Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Simon I R Lane (SIR)

School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Institute for Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Magdalena C Vidale (MC)

School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Bhavwanti Sheth (B)

School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Joel D Allen (JD)

School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Maria V Humbert (MV)

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Sir Henry Wellcome Laboratories, University Hospital Southampton, Southampton SO16 6YD, United Kingdom.
University of Cambridge, MRC Toxicology Unit, Cambridge, CB2 1QR, United Kingdom.

Cosma M Spalluto (CM)

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Sir Henry Wellcome Laboratories, University Hospital Southampton, Southampton SO16 6YD, United Kingdom.
Southampton NIHR Biomedical Research Centre, Southampton General Hospital, Southampton SO16 6YD, United Kingdom.

Rodolphe C Hervé (RC)

School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Karl Staples (K)

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Sir Henry Wellcome Laboratories, University Hospital Southampton, Southampton SO16 6YD, United Kingdom.
Wessex Investigational Sciences Hub, University of Southampton Faculty of Medicine, Southampton General Hospital, Southampton SO16 6YD, United Kingdom.
Southampton NIHR Biomedical Research Centre, Southampton General Hospital, Southampton SO16 6YD, United Kingdom.

Jonathan J West (JJ)

Institute for Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom.

Robert Forster (R)

M Squared Lasers, Limited, 1 K Campus, West of Scotland Science Park, Glasgow, G20 0SP, United Kingdom.

Nullin Divecha (N)

School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Christopher J McCormick (CJ)

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Sir Henry Wellcome Laboratories, University Hospital Southampton, Southampton SO16 6YD, United Kingdom.

Max Crispin (M)

School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.

Nils Hempler (N)

M Squared Lasers, Limited, 1 K Campus, West of Scotland Science Park, Glasgow, G20 0SP, United Kingdom.

Graeme P A Malcolm (GPA)

M Squared Lasers, Limited, 1 K Campus, West of Scotland Science Park, Glasgow, G20 0SP, United Kingdom.

Sumeet Mahajan (S)

School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Institute for Life Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Department of Biotechnology, Inland Norway University of Applied Sciences, Holsetgata 22, N-2317 Hamar, Norway.

Classifications MeSH