An In Vitro Model to Assess Early Immune Markers Following Co-Exposure of Epithelial Cells to Carbon Black (Nano)Particles in the Presence of

A549 HaCaT Staphylococcus aureus carbon black (nano)particles cytokines epithelial cells in vitro co-exposure models infection particle exposure

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
08 Jan 2024
Historique:
received: 24 11 2023
revised: 21 12 2023
accepted: 25 12 2023
medline: 23 1 2024
pubmed: 23 1 2024
entrez: 23 1 2024
Statut: epublish

Résumé

The exposure of human lung and skin to carbon black (CB) is continuous due to its widespread applications. Current toxicological testing uses 'healthy' cellular systems; however, questions remain whether this mimics the everyday stresses that human cells are exposed to, including infection.

Identifiants

pubmed: 38255233
pii: biomedicines12010128
doi: 10.3390/biomedicines12010128
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : The work was partly funded by a studentship from SUMS to TSW.
ID : None
Organisme : MJDC and KM acknowledge the financial support from the SPF Clean Air Challenge Funded (UKRI NERC) project, RESPIRE (NE/W002264/1).
ID : NE/W002264/1

Auteurs

Scott Brown (S)

Microbiology and Infectious Disease, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Stephen J Evans (SJ)

In Vitro Toxicology Group, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Michael J Burgum (MJ)

In Vitro Toxicology Group, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Kirsty Meldrum (K)

In Vitro Toxicology Group, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Jack Herridge (J)

Microbiology and Infectious Disease, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Blessing Akinbola (B)

Microbiology and Infectious Disease, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Llinos G Harris (LG)

Microbiology and Infectious Disease, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Rowena Jenkins (R)

Microbiology and Infectious Disease, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Shareen H Doak (SH)

In Vitro Toxicology Group, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Martin J D Clift (MJD)

In Vitro Toxicology Group, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Thomas S Wilkinson (TS)

Microbiology and Infectious Disease, Institute of Life Science, Swansea University Medical School (SUMS), Swansea SA2 8PP, UK.

Classifications MeSH