Phytochemicals from the Stem Bark of Calophyllum havilandii P. F. Stevens and their Biological Activities.
Calophyllum
anti-bacillus
chromanone
coumarin
cytotoxicity •
Journal
Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
received:
02
12
2023
accepted:
23
01
2024
medline:
18
3
2024
pubmed:
25
1
2024
entrez:
25
1
2024
Statut:
ppublish
Résumé
The genus Calophyllum from the family Calophyllaceae has been extensively investigated in the past due to its rich source of bioactive phenolics such as coumarins, chromanones, and xanthones. In this study, phytochemical investigation on the stem bark of Calophyllum havilandii has afforded a new 4-propyldihydrocoumarin derivative, havilarin (1) together with calolongic acid (2), caloteysmannic acid (3), isocalolongic acid (4), euxanthone (5), and β-sitosterol (6). The chemical structure of compound 1 was elucidated and established based on detailed spectroscopic techniques, including MS, IR, UV, 1D and 2D NMR. The results of anti-bacillus study indicated that the chloroform extract showed promising activities with MIC value ranging between 0.5 to 1 μg/mL on selected bacillus strains. Besides, the plant extracts and compounds 1-4 were assessed for their cytotoxicity potential on HL-7702 cell line. All the tested plant extracts and respective chemical constituents displayed non-cytotoxic activity on HL-7702 cell line.
Identifiants
pubmed: 38268343
doi: 10.1002/cbdv.202301936
doi:
Substances chimiques
Plant Extracts
0
Phytochemicals
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202301936Subventions
Organisme : Centre for Drug Research (CDR)
Organisme : Universiti Sains Malaysia
Organisme : Sarawak Biodiversity Centre (SBC)
Informations de copyright
© 2024 Wiley-VHCA AG, Zurich, Switzerland.
Références
S. Gupta, P. Gupta, in ‘Bioactive Natural products in Drug Discovery’, Springer (New York); 2020. p. 215-242.
A. A. D. Zailan, T. Karunakaran, M. H. Abu Bakar, V. J. Y. Mian, Nat. Prod. Res. 2022, 36, 4575-4585.
P. F. Stevens, J. Arnold Arbor. 1980, 61, 117-424.
Y. Kashman, K. R. Gustafson, R. W. Fuller, J. H. Cardellina 2nd, J. B. McMahon, M. J. Currens, R. W. Buckheit Jr., S. H. Hughes, G. M. Cragg, M. R. Boyd, J. Med. Chem. 1992, 35, 2735-2743.
M. A. Lizazman, V. Y. M. Jong, P. Chua, W. K. Lim, T. Karunakaran, Nat. Prod. Res. 2022, 1-6.
M. Taher, W. Salleh, S. I. Alkhamaiseh, F. Ahmad, M. F. Rezali, D. Susanti, C. M. Hasan, Z. Naturforsch. C 2021, 76, 87-91.
N. I. Aminudin, F. Ahmad, M. Taher, R. M. Zulkifli, J. Appl. Pharmacol. 2016, 6, 1.
T. Karunakaran, N. S. Firouz, R. Santhanam, V. Y. M. Jong, Nat. Prod. Res. 2022, 36, 654-659.
N. H. Zamakshshari, G. C. L. Ee, I. S. Ismail, Z. Ibrahim, S. H. Mah, Food Chem. Toxicol. 2019, 133, 110800.
S. Daud, T. Karunakaran, R. Santhanam, S. R. Nagaratnam, V. Y. M. Jong, G. C. L. Ee, Nat. Prod. Res. 2021, 35, 6067-6072.
K. W. Lee, G. C. L. Ee, S. Daud, T. Karunakaran, Pertanika J. Trop. Agric. Sci. 2017, 40, 111-118.
G. C. L. Ee, K. Ng, Y. H. Taufiq-Yap, M. Rahmani, A. Ali, R. Muse, Nat. Prod. Res. 2004, 18, 123-128.
L. Ferchichi, S. Derbré, K. Mahmood, K. Touré, D. Guilet, M. Litaudon, K. Awang, A. H. A. Hadi, A. M. Le Ray, P. Richomme, Phytochemistry 2012, 78, 98-106.
L. K. Omosa, J. O. Midiwo, A. T. Mbaveng, S. B. Tankeo, J. A. Seukep, I. K. Voukeng, J. K. Dzotam, J. Isemeki, S. Derese, R. A. Omolle, T. Efferth, V. Kuete, Springerplus 2016, 5, 90.
S. Shanmugapriya, Y. Chen, J. R. Kanwar, S. Sasidharan, Bioorg. Chem. 2020, 97, 103699.
Y. P. Liu, G. Yan, Y. T. Xie, T. C. Lin, W. Zhang, J. Li, Y. J. Wu, J. Y. Zhou, Y. H. Fu, Bioorg. Chem. 2020, 97, 103699.
M. Huerta-Reyes, M. C. Basualdo, F. Abe, M. Jimenez-Estrada, C. Soler, R. Reyes-Chilpa, Biol. Pharm. Bull. 2004, 27, 1471-1475.
Y. C. Shen, L. T. Wang, K. Y. H. Khalil, Nat. Prod. Res. 2021, 1-5.
L. G. Silva, K. S. Gomes, T. A. Costa-Silva, M. M. Romanelli, A. G. Tempone, P. Sartorelli, J. H. G. Lago, Nat. Prod. Res. 2021, 1-5.
C. Ito, K. Fujiwara, M. Kajita, M. Ju-Ichi, Y. Takemura, Y. Suzuki, K. Tanaka, M. Omura, H. Furukawa, Academic Press, 2017. p. 207-237.
D. D. Tamokou, A. T. Mbaveng, V. Kuete, Academic Press, 2017. p. 207-237.
T. S. Tjahjandarie, W. A. S. Nugroho, H. Palgunadi, R. D. Saputri, M. Tanjung, Nat. Prod. Res. 2022, 1-6.
S. Kamboj, R. Singh, Results Chem. 2022, 4, 100276.
X. Liu, J. Shen, K. Zhu, RSC Med. Chem. 2022,13, 107-116.
H. L. Qin, Z. W. Zhang, L. Ravindar, K. P. Rakesh, Eur. J. Med. Chem. 2020, 207, 112832.
S. Mizuno, R. Miyata, K. Mukaide, S. Honda, A. Sukito, M. Sahlan, T. Tanaguchi, S. Kumazawa, Results Chem. 2022, 4, 100276.
S. Mizuno, R. Miyata, K. Mukaide, A. Sukito, M. Sahlan, T. Tanaguchi, M. Sahlan, S. Kumazawa, Rec. Nat. Prod. 2023.
F. Cottiglia, B. Dhanapal, O. Sticher, J. Heilmann, J. Nat. Prod. 2004, 67(4), 537-41.
M. Tanjung, F. Rachmadiarti, R. D. Saputri, T. S. Tjahjandarie, Nat. Prod. Res. 2018, 32, 1062-1067.
N. Mokhtar, T. Karunakaran, R. Santhanam, M. H. Abu Bakar, V. Y. M. Jong, Nat. Prod. Res. 2023, 1-6.
M. A. Lizazman, V. Y. M. Jong, P. Chua, W. K. Lim, T. Karunakaran, Nat. Prod. Res. 2022, 1-6.