Notch3 directs differentiation of brain mural cells from human pluripotent stem cell-derived neural crest.

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
02 Feb 2024
Historique:
medline: 2 2 2024
pubmed: 2 2 2024
entrez: 2 2 2024
Statut: ppublish

Résumé

Brain mural cells regulate development and function of the blood-brain barrier and control blood flow. Existing in vitro models of human brain mural cells have low expression of key mural cell genes, including

Identifiants

DOI: 10.1126/sciadv.adi1737 PMID: 38306433
pubmed: 38306433
doi: 10.1126/sciadv.adi1737
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadi1737

Auteurs

Benjamin D Gastfriend (BD)

Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
ORCID: 0000-0002-4677-1455

Margaret E Snyder (ME)

Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.

Hope E Holt (HE)

Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
ORCID: 0000-0002-4287-1504

Richard Daneman (R)

Departments of Neurosciences and Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.
ORCID: 0000-0002-7749-6353

Sean P Palecek (SP)

Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
ORCID: 0000-0003-4917-5584

Eric V Shusta (EV)

Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
Department of Neurological Surgery, University of Wisconsin-Madison, Madison, WI 53706, USA.
ORCID: 0000-0002-4297-0158

Classifications MeSH