Richard Daneman

Affiliations

Departments of Pharmacology and Neurosciences, University of California, San Diego, San Diego, CA, USA. Rdaneman@ucsd.edu.

ORCID: http://orcid.org/0000-0002-7749-6353

Publications (13)

Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module.

Nature neuroscience

Avec: Roeben Nocon Munji , Allison Luen Soung , Geoffrey Aaron Weiner , Fabien Sohet , Bridgette Deanne Semple , Alpa Trivedi , Kayleen Gimlin , Masakazu Kotoda , Masaaki Korai , Sidar Aydin , Austin Batugal , Anne Christelle Cabangcala , Patrick Georg Schupp , Michael Clark Oldham , Tomoki Hashimoto , Linda J Noble-Haeusslein , Richard Daneman

Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation.

Nature communications

Avec: G A Weiner , S H Shah , C M Angelopoulos , A B Bartakova , R S Pulido , A Murphy , E Nudleman , R Daneman , J L Goldberg

Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism.

Neuron

Avec: Caterina P Profaci , Sean S Harvey , Kaja Bajc , Tony Z Zhang , Danielle A Jeffrey , Alexander Z Zhang , Kelsey M Nemec , Hayk Davtyan , Carleigh A O'Brien , Gabriel L McKinsey , Aaron Longworth , Timothy P McMullen , Joia K Capocchi , Jessica G Gonzalez , Devon A Lawson , Thomas D Arnold , Dimitrios Davalos , Mathew Blurton-Jones , Fabrice Dabertrand , F Chris Bennett , Richard Daneman

Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege.

The Journal of clinical investigation

Avec: Yinghua Ma , David Sannino , Jennifer R Linden , Sylvia Haigh , Baohua Zhao , John B Grigg , Paul Zumbo , Friederike Dündar , Daniel Butler , Caterina P Profaci , Kiel Telesford , Paige N Winokur , Kareem R Rumah , Susan A Gauthier , Vincent A Fischetti , Bruce A McClane , Francisco A Uzal , Lily Zexter , Michael Mazzucco , Richard Rudick , David Danko , Evan Balmuth , Nancy Nealon , Jai Perumal , Ulrike Kaunzner , Ilana L Brito , Zhengming Chen , Jenny Z Xiang , Doron Betel , Richard Daneman , Gregory F Sonnenberg , Christopher E Mason , Timothy Vartanian

Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids.

PloS one

Avec: Qin Huang , Ken Y Chan , Isabelle G Tobey , Yujia Alina Chan , Tim Poterba , Christine L Boutros , Alejandro B Balazs , Richard Daneman , Jonathan M Bloom , Cotton Seed , Benjamin E Deverman

Emerging roles for CNS fibroblasts in health, injury and disease.

Nature reviews. Neuroscience

Avec: Cayce E Dorrier , Hannah E Jones , Lucija Pintarić , Julie A Siegenthaler , Richard Daneman

Distinct features of brain perivascular fibroblasts and mural cells revealed by

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Avec: Stephanie K Bonney , Liam T Sullivan , Timothy J Cherry , Richard Daneman , Andy Y Shih

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration.

Nature neuroscience

Avec: Cayce E Dorrier , Dvir Aran , Ezekiel A Haenelt , Ryan N Sheehy , Kimberly K Hoi , Lucija Pintarić , Yanan Chen , Carlos O Lizama , Kelly M Cautivo , Geoffrey A Weiner , Brian Popko , Stephen P J Fancy , Thomas D Arnold , Richard Daneman

Specification of CNS macrophage subsets occurs postnatally in defined niches.

Nature

Avec: Takahiro Masuda , Lukas Amann , Gianni Monaco , Roman Sankowski , Ori Staszewski , Martin Krueger , Francesca Del Gaudio , Liqun He , Neil Paterson , Elisa Nent , Francisco Fernández-Klett , Ayato Yamasaki , Maximilian Frosch , Maximilian Fliegauf , Lance Fredrick Pahutan Bosch , Hatice Ulupinar , Nora Hagemeyer , Dietmar Schreiner , Cayce Dorrier , Makoto Tsuda , Claudia Grothe , Anne Joutel , Richard Daneman , Christer Betsholtz , Urban Lendahl , Klaus-Peter Knobeloch , Tim Lämmermann , Josef Priller , Katrin Kierdorf , Marco Prinz

Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation.

The Journal of clinical investigation

Avec: Miguel Alejandro Lopez-Ramirez , Catherine Chinhchu Lai , Shady Ibrahim Soliman , Preston Hale , Angela Pham , Esau J Estrada , Sara McCurdy , Romuald Girard , Riya Verma , Thomas Moore , Rhonda Lightle , Nicholas Hobson , Robert Shenkar , Orit Poulsen , Gabriel G Haddad , Richard Daneman , Brendan Gongol , Hao Sun , Frederic Lagarrigue , Issam A Awad , Mark H Ginsberg

Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes.

Neuron

Avec: Robert S Pulido , Roeben N Munji , Tamara C Chan , Clare R Quirk , Geoffrey A Weiner , Benjamin D Weger , Meghan J Rossi , Sara Elmsaouri , Mario Malfavon , Aaron Deng , Caterina P Profaci , Marie Blanchette , Tongcheng Qian , Koji L Foreman , Eric V Shusta , Michael R Gorman , Frédéric Gachon , Stefan Leutgeb , Richard Daneman

Notch3 directs differentiation of brain mural cells from human pluripotent stem cell-derived neural crest.

Science advances

Avec: Benjamin D Gastfriend , Margaret E Snyder , Hope E Holt , Richard Daneman , Sean P Palecek , Eric V Shusta

CD98hc is a target for brain delivery of biotherapeutics.

Nature communications

Avec: Kylie S Chew , Robert C Wells , Arash Moshkforoush , Darren Chan , Kendra J Lechtenberg , Hai L Tran , Johann Chow , Do Jin Kim , Yaneth Robles-Colmenares , Devendra B Srivastava , Raymond K Tong , Mabel Tong , Kaitlin Xa , Alexander Yang , Yinhan Zhou , Padma Akkapeddi , Lakshman Annamalai , Kaja Bajc , Marie Blanchette , Gerald Maxwell Cherf , Timothy K Earr , Audrey Gill , David Huynh , David Joy , Kristen N Knight , Diana Lac , Amy Wing-Sze Leung , Katrina W Lexa , Nicholas P D Liau , Isabel Becerra , Mario Malfavon , Joseph McInnes , Hoang N Nguyen , Edwin I Lozano , Michelle E Pizzo , Elysia Roche , Patricia Sacayon , Meredith E K Calvert , Richard Daneman , Mark S Dennis , Joseph Duque , Kapil Gadkar , Joseph W Lewcock , Cathal S Mahon , René Meisner , Hilda Solanoy , Robert G Thorne , Ryan J Watts , Y Joy Yu Zuchero , Mihalis S Kariolis

Réseau de co-auteurs

Caterina P Profaci 3 collaborations

Kaja Bajc 2 collaborations

Thomas D Arnold 2 collaborations

Cayce E Dorrier 2 collaborations

Lucija Pintarić 2 collaborations

Geoffrey A Weiner 2 collaborations

Mario Malfavon 2 collaborations

Marie Blanchette 2 collaborations

Eric V Shusta 2 collaborations

Roeben Nocon Munji 1 collaboration

Allison Luen Soung 1 collaboration

Geoffrey Aaron Weiner 1 collaboration

Fabien Sohet 1 collaboration

Bridgette Deanne Semple 1 collaboration

Alpa Trivedi 1 collaboration

Kayleen Gimlin 1 collaboration

Masakazu Kotoda 1 collaboration

Masaaki Korai 1 collaboration

Sidar Aydin 1 collaboration

Austin Batugal 1 collaboration

Anne Christelle Cabangcala 1 collaboration

Patrick Georg Schupp 1 collaboration

Michael Clark Oldham 1 collaboration

Tomoki Hashimoto 1 collaboration

Linda J Noble-Haeusslein 1 collaboration

G A Weiner 1 collaboration

S H Shah 1 collaboration

C M Angelopoulos 1 collaboration

A B Bartakova 1 collaboration

R S Pulido 1 collaboration

A Murphy 1 collaboration

E Nudleman 1 collaboration

R Daneman 1 collaboration

J L Goldberg 1 collaboration

Sean S Harvey 1 collaboration

Tony Z Zhang 1 collaboration

Danielle A Jeffrey 1 collaboration

Alexander Z Zhang 1 collaboration

Kelsey M Nemec 1 collaboration

Hayk Davtyan 1 collaboration

Carleigh A O'Brien 1 collaboration

Gabriel L McKinsey 1 collaboration

Aaron Longworth 1 collaboration

Timothy P McMullen 1 collaboration

Joia K Capocchi 1 collaboration

Jessica G Gonzalez 1 collaboration

Devon A Lawson 1 collaboration

Dimitrios Davalos 1 collaboration

Mathew Blurton-Jones 1 collaboration

Fabrice Dabertrand 1 collaboration

F Chris Bennett 1 collaboration

Yinghua Ma 1 collaboration

David Sannino 1 collaboration

Jennifer R Linden 1 collaboration

Sylvia Haigh 1 collaboration

Baohua Zhao 1 collaboration

John B Grigg 1 collaboration

Paul Zumbo 1 collaboration

Friederike Dündar 1 collaboration

Daniel Butler 1 collaboration

Kiel Telesford 1 collaboration

Paige N Winokur 1 collaboration

Kareem R Rumah 1 collaboration

Susan A Gauthier 1 collaboration

Vincent A Fischetti 1 collaboration

Bruce A McClane 1 collaboration

Francisco A Uzal 1 collaboration

Lily Zexter 1 collaboration

Michael Mazzucco 1 collaboration

Richard Rudick 1 collaboration

David Danko 1 collaboration

Evan Balmuth 1 collaboration

Nancy Nealon 1 collaboration

Jai Perumal 1 collaboration

Ulrike Kaunzner 1 collaboration

Ilana L Brito 1 collaboration

Zhengming Chen 1 collaboration

Jenny Z Xiang 1 collaboration

Doron Betel 1 collaboration

Gregory F Sonnenberg 1 collaboration

Christopher E Mason 1 collaboration

Timothy Vartanian 1 collaboration

Qin Huang 1 collaboration

Ken Y Chan 1 collaboration

Isabelle G Tobey 1 collaboration

Yujia Alina Chan 1 collaboration

Tim Poterba 1 collaboration

Christine L Boutros 1 collaboration

Alejandro B Balazs 1 collaboration

Jonathan M Bloom 1 collaboration

Cotton Seed 1 collaboration

Benjamin E Deverman 1 collaboration

Hannah E Jones 1 collaboration

Julie A Siegenthaler 1 collaboration

Stephanie K Bonney 1 collaboration

Liam T Sullivan 1 collaboration

Timothy J Cherry 1 collaboration

Andy Y Shih 1 collaboration

Dvir Aran 1 collaboration

Ezekiel A Haenelt 1 collaboration

Ryan N Sheehy 1 collaboration

Kimberly K Hoi 1 collaboration

Yanan Chen 1 collaboration

Carlos O Lizama 1 collaboration

Kelly M Cautivo 1 collaboration

Brian Popko 1 collaboration

Stephen P J Fancy 1 collaboration

Takahiro Masuda 1 collaboration

Lukas Amann 1 collaboration

Gianni Monaco 1 collaboration

Roman Sankowski 1 collaboration

Ori Staszewski 1 collaboration

Martin Krueger 1 collaboration

Francesca Del Gaudio 1 collaboration

Liqun He 1 collaboration

Neil Paterson 1 collaboration

Elisa Nent 1 collaboration

Francisco Fernández-Klett 1 collaboration

Ayato Yamasaki 1 collaboration

Maximilian Frosch 1 collaboration

Maximilian Fliegauf 1 collaboration

Lance Fredrick Pahutan Bosch 1 collaboration

Hatice Ulupinar 1 collaboration

Nora Hagemeyer 1 collaboration

Dietmar Schreiner 1 collaboration

Cayce Dorrier 1 collaboration

Makoto Tsuda 1 collaboration

Claudia Grothe 1 collaboration

Anne Joutel 1 collaboration

Christer Betsholtz 1 collaboration

Urban Lendahl 1 collaboration

Klaus-Peter Knobeloch 1 collaboration

Tim Lämmermann 1 collaboration

Josef Priller 1 collaboration

Katrin Kierdorf 1 collaboration

Marco Prinz 1 collaboration

Miguel Alejandro Lopez-Ramirez 1 collaboration

Catherine Chinhchu Lai 1 collaboration

Shady Ibrahim Soliman 1 collaboration

Preston Hale 1 collaboration

Angela Pham 1 collaboration

Esau J Estrada 1 collaboration

Sara McCurdy 1 collaboration

Romuald Girard 1 collaboration

Riya Verma 1 collaboration

Thomas Moore 1 collaboration

Rhonda Lightle 1 collaboration

Nicholas Hobson 1 collaboration

Robert Shenkar 1 collaboration

Orit Poulsen 1 collaboration

Gabriel G Haddad 1 collaboration

Brendan Gongol 1 collaboration

Hao Sun 1 collaboration

Frederic Lagarrigue 1 collaboration

Issam A Awad 1 collaboration

Mark H Ginsberg 1 collaboration

Robert S Pulido 1 collaboration

Roeben N Munji 1 collaboration

Tamara C Chan 1 collaboration

Clare R Quirk 1 collaboration

Benjamin D Weger 1 collaboration

Meghan J Rossi 1 collaboration

Sara Elmsaouri 1 collaboration

Aaron Deng 1 collaboration

Tongcheng Qian 1 collaboration

Koji L Foreman 1 collaboration

Michael R Gorman 1 collaboration

Frédéric Gachon 1 collaboration

Stefan Leutgeb 1 collaboration

Benjamin D Gastfriend 1 collaboration

Margaret E Snyder 1 collaboration

Hope E Holt 1 collaboration

Sean P Palecek 1 collaboration

Kylie S Chew 1 collaboration

Robert C Wells 1 collaboration

Arash Moshkforoush 1 collaboration

Darren Chan 1 collaboration

Kendra J Lechtenberg 1 collaboration

Hai L Tran 1 collaboration

Johann Chow 1 collaboration

Do Jin Kim 1 collaboration

Yaneth Robles-Colmenares 1 collaboration

Devendra B Srivastava 1 collaboration

Raymond K Tong 1 collaboration

Mabel Tong 1 collaboration

Kaitlin Xa 1 collaboration

Alexander Yang 1 collaboration

Yinhan Zhou 1 collaboration

Padma Akkapeddi 1 collaboration

Lakshman Annamalai 1 collaboration

Gerald Maxwell Cherf 1 collaboration

Timothy K Earr 1 collaboration

Audrey Gill 1 collaboration

David Huynh 1 collaboration

David Joy 1 collaboration

Kristen N Knight 1 collaboration

Diana Lac 1 collaboration

Amy Wing-Sze Leung 1 collaboration

Katrina W Lexa 1 collaboration

Nicholas P D Liau 1 collaboration

Isabel Becerra 1 collaboration

Joseph McInnes 1 collaboration

Hoang N Nguyen 1 collaboration

Edwin I Lozano 1 collaboration

Michelle E Pizzo 1 collaboration

Elysia Roche 1 collaboration

Patricia Sacayon 1 collaboration

Meredith E K Calvert 1 collaboration

Mark S Dennis 1 collaboration

Joseph Duque 1 collaboration

Kapil Gadkar 1 collaboration

Joseph W Lewcock 1 collaboration

Cathal S Mahon 1 collaboration

René Meisner 1 collaboration

Hilda Solanoy 1 collaboration

Robert G Thorne 1 collaboration

Ryan J Watts 1 collaboration

Y Joy Yu Zuchero 1 collaboration

Mihalis S Kariolis 1 collaboration