Brian Popko

Affiliations

Department of Neurology, Division of Multiple Sclerosis and Neuroimmunology, Northwestern University Feinberg School of Medicine, Chicago, United States.

ORCID: 0000-0001-9948-2553

Publications (18)

Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment.

eLife

Avec: Yanan Chen , Rejani B Kunjamma , Molly Weiner , Jonah R Chan , Brian Popko

Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response.

Glia

Avec: Yanan Chen , Songhua Quan , Vaibhav Patil , Rejani B Kunjamma , Haley M Tokars , Eric D Leisten , Godwin Joy , Samantha Wills , Jonah R Chan , Yvette C Wong , Brian Popko

Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis.

Brain : a journal of neurology

Avec: Yanan Chen , Joseph R Podojil , Rejani B Kunjamma , Joshua Jones , Molly Weiner , Wensheng Lin , Stephen D Miller , Brian Popko

Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease.

Immunity

Avec: Sebastian Werneburg , Jonathan Jung , Rejani B Kunjamma , Seung-Kwon Ha , Nicholas J Luciano , Cory M Willis , Guangping Gao , Natalia P Biscola , Leif A Havton , Stephen J Crocker , Brian Popko , Daniel S Reich , Dorothy P Schafer

Sensory neurons display cell-type-specific vulnerability to loss of neuron-glia interactions.

Cell reports

Avec: Benayahu Elbaz , Lite Yang , Maia Vardy , Sara Isaac , Braesen L Rader , Riki Kawaguchi , Maria Traka , Clifford J Woolf , William Renthal , Brian Popko

Evaluation of the potassium channel tracer [

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Avec: Nicolas J Guehl , Karla M Ramos-Torres , Clas Linnman , Sung-Hyun Moon , Maeva Dhaynaut , Moses Q Wilks , Paul K Han , Chao Ma , Ramesh Neelamegam , Yu-Peng Zhou , Brian Popko , John A Correia , Daniel S Reich , Georges El Fakhri , Peter Herscovitch , Marc D Normandin , Pedro Brugarolas

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration.

Nature neuroscience

Avec: Cayce E Dorrier , Dvir Aran , Ezekiel A Haenelt , Ryan N Sheehy , Kimberly K Hoi , Lucija Pintarić , Yanan Chen , Carlos O Lizama , Kelly M Cautivo , Geoffrey A Weiner , Brian Popko , Stephen P J Fancy , Thomas D Arnold , Richard Daneman

Resolving inflammatory links between myocardial infarction and vascular dementia.

Seminars in immunology

Avec: Edward B Thorp , Margaret E Flanagan , Brian Popko , Matthew DeBerge

Interferon-γ controls aquaporin-4-specific Th17 and B cells in neuromyelitis optica spectrum disorder.

Brain : a journal of neurology

Avec: Gabriel Arellano , Eileah Loda , Yanan Chen , Tobias Neef , Andrew C Cogswell , Grant Primer , Godwin Joy , Kevin Kaschke , Samantha Wills , Joseph R Podojil , Brian Popko , Roumen Balabanov , Stephen D Miller

CCR2

Brain, behavior, and immunity

Avec: Edward B Thorp , Mallory Filipp , Maria Dima , Chunfeng Tan , Matthew Feinstein , Brian Popko , Matthew DeBerge

Pre-clinical and Clinical Implications of "Inside-Out" vs. "Outside-In" Paradigms in Multiple Sclerosis Etiopathogenesis.

Frontiers in cellular neuroscience

Avec: Haley E Titus , Yanan Chen , Joseph R Podojil , Andrew P Robinson , Roumen Balabanov , Brian Popko , Stephen D Miller

Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.

Glia

Avec: Haley E Titus , Huan Xu , Andrew P Robinson , Priyam A Patel , Yanan Chen , Damiano Fantini , Valerie Eaton , Molly Karl , Eric D Garrison , Indigo V L Rose , Ming Yi Chiang , Joseph R Podojil , Roumen Balabanov , Shane A Liddelow , Robert H Miller , Brian Popko , Stephen D Miller

Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response.

bioRxiv : the preprint server for biology

Avec: Yanan Chen , Songhua Quan , Vaibhav Patil , Rejani B Kunjamma , Haley M Tokars , Eric D Leisten , Jonah Chan , Yvette Wong , Brian Popko

Molecular Control of Oligodendrocyte Development.

Trends in neurosciences

Avec: Benayahu Elbaz , Brian Popko

The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS.

Neurobiology of disease

Avec: Yulia Dzhashiashvili , Chase P Monckton , Harini S Shah , Rejani B Kunjamma , Brian Popko

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Neuron

Avec: Huan Xu , Yulia Dzhashiashvili , Ankeeta Shah , Rejani B Kunjamma , Yi-Lan Weng , Benayahu Elbaz , Qili Fei , Joshua S Jones , Yang I Li , Xiaoxi Zhuang , Guo-Li Ming , Chuan He , Brian Popko

The bone transcription factor Osterix controls extracellular matrix- and node of Ranvier-related gene expression in oligodendrocytes.

Neuron

Avec: Benayahu Elbaz , Alaa Darwish , Maia Vardy , Sara Isaac , Haley Margaret Tokars , Yulia Dzhashiashvili , Kirill Korshunov , Murali Prakriya , Amir Eden , Brian Popko

Oligodendroglial fatty acid metabolism as a central nervous system energy reserve.

Nature neuroscience

Avec: Ebrahim Asadollahi , Andrea Trevisiol , Aiman S Saab , Zoe J Looser , Payam Dibaj , Reyhane Ebrahimi , Kathrin Kusch , Torben Ruhwedel , Wiebke Möbius , Olaf Jahn , Jun Yup Lee , Anthony S Don , Michelle-Amirah Khalil , Karsten Hiller , Myriam Baes , Bruno Weber , E Dale Abel , Andrea Balabio , Brian Popko , Celia M Kassmann , Hannelore Ehrenreich , Johannes Hirrlinger , Klaus-Armin Nave

Réseau de co-auteurs

Yanan Chen 8 collaborations

Rejani B Kunjamma 7 collaborations

Joseph R Podojil 4 collaborations

Stephen D Miller 4 collaborations

Benayahu Elbaz 4 collaborations

Roumen Balabanov 3 collaborations

Yulia Dzhashiashvili 3 collaborations

Molly Weiner 2 collaborations

Jonah R Chan 2 collaborations

Songhua Quan 2 collaborations

Vaibhav Patil 2 collaborations

Haley M Tokars 2 collaborations

Eric D Leisten 2 collaborations

Godwin Joy 2 collaborations

Samantha Wills 2 collaborations

Daniel S Reich 2 collaborations

Maia Vardy 2 collaborations

Sara Isaac 2 collaborations

Edward B Thorp 2 collaborations

Matthew DeBerge 2 collaborations

Haley E Titus 2 collaborations

Andrew P Robinson 2 collaborations

Huan Xu 2 collaborations

Yvette C Wong 1 collaboration

Joshua Jones 1 collaboration

Wensheng Lin 1 collaboration

Sebastian Werneburg 1 collaboration

Jonathan Jung 1 collaboration

Seung-Kwon Ha 1 collaboration

Nicholas J Luciano 1 collaboration

Cory M Willis 1 collaboration

Guangping Gao 1 collaboration

Natalia P Biscola 1 collaboration

Leif A Havton 1 collaboration

Stephen J Crocker 1 collaboration

Dorothy P Schafer 1 collaboration

Lite Yang 1 collaboration

Braesen L Rader 1 collaboration

Riki Kawaguchi 1 collaboration

Maria Traka 1 collaboration

Clifford J Woolf 1 collaboration

William Renthal 1 collaboration

Nicolas J Guehl 1 collaboration

Karla M Ramos-Torres 1 collaboration

Clas Linnman 1 collaboration

Sung-Hyun Moon 1 collaboration

Maeva Dhaynaut 1 collaboration

Moses Q Wilks 1 collaboration

Paul K Han 1 collaboration

Chao Ma 1 collaboration

Ramesh Neelamegam 1 collaboration

Yu-Peng Zhou 1 collaboration

John A Correia 1 collaboration

Georges El Fakhri 1 collaboration

Peter Herscovitch 1 collaboration

Marc D Normandin 1 collaboration

Pedro Brugarolas 1 collaboration

Cayce E Dorrier 1 collaboration

Dvir Aran 1 collaboration

Ezekiel A Haenelt 1 collaboration

Ryan N Sheehy 1 collaboration

Kimberly K Hoi 1 collaboration

Lucija Pintarić 1 collaboration

Carlos O Lizama 1 collaboration

Kelly M Cautivo 1 collaboration

Geoffrey A Weiner 1 collaboration

Stephen P J Fancy 1 collaboration

Thomas D Arnold 1 collaboration

Richard Daneman 1 collaboration

Margaret E Flanagan 1 collaboration

Gabriel Arellano 1 collaboration

Eileah Loda 1 collaboration

Tobias Neef 1 collaboration

Andrew C Cogswell 1 collaboration

Grant Primer 1 collaboration

Kevin Kaschke 1 collaboration

Mallory Filipp 1 collaboration

Maria Dima 1 collaboration

Chunfeng Tan 1 collaboration

Matthew Feinstein 1 collaboration

Priyam A Patel 1 collaboration

Damiano Fantini 1 collaboration

Valerie Eaton 1 collaboration

Molly Karl 1 collaboration

Eric D Garrison 1 collaboration

Indigo V L Rose 1 collaboration

Ming Yi Chiang 1 collaboration

Shane A Liddelow 1 collaboration

Robert H Miller 1 collaboration

Jonah Chan 1 collaboration

Yvette Wong 1 collaboration

Chase P Monckton 1 collaboration

Harini S Shah 1 collaboration

Ankeeta Shah 1 collaboration

Yi-Lan Weng 1 collaboration

Qili Fei 1 collaboration

Joshua S Jones 1 collaboration

Yang I Li 1 collaboration

Xiaoxi Zhuang 1 collaboration

Guo-Li Ming 1 collaboration

Chuan He 1 collaboration

Alaa Darwish 1 collaboration

Haley Margaret Tokars 1 collaboration

Kirill Korshunov 1 collaboration

Murali Prakriya 1 collaboration

Amir Eden 1 collaboration

Ebrahim Asadollahi 1 collaboration

Andrea Trevisiol 1 collaboration

Aiman S Saab 1 collaboration

Zoe J Looser 1 collaboration

Payam Dibaj 1 collaboration

Reyhane Ebrahimi 1 collaboration

Kathrin Kusch 1 collaboration

Torben Ruhwedel 1 collaboration

Wiebke Möbius 1 collaboration

Olaf Jahn 1 collaboration

Jun Yup Lee 1 collaboration

Anthony S Don 1 collaboration

Michelle-Amirah Khalil 1 collaboration

Karsten Hiller 1 collaboration

Myriam Baes 1 collaboration

Bruno Weber 1 collaboration

E Dale Abel 1 collaboration

Andrea Balabio 1 collaboration

Celia M Kassmann 1 collaboration

Hannelore Ehrenreich 1 collaboration

Johannes Hirrlinger 1 collaboration

Klaus-Armin Nave 1 collaboration