Expression of lymphocyte activation gene-3 on CD4

Humans Cytokines Interleukin-18 Lymphocyte Activation Myasthenia Gravis T-Lymphocytes
CD4(+)T cell IL-18 LAG-3 Myasthenia gravis

Journal

Journal of neuroimmunology
ISSN: 1872-8421
Titre abrégé: J Neuroimmunol
Pays: Netherlands
ID NLM: 8109498

Informations de publication

Date de publication:
15 03 2024
Historique:
received: 01 10 2023
revised: 18 01 2024
accepted: 31 01 2024
medline: 8 3 2024
pubmed: 8 2 2024
entrez: 7 2 2024
Statut: ppublish

Résumé

Myasthenia gravis (MG) is a T cell-dependent, B cell-mediated, and complement-dependent autoimmune disease. Lymphocyte activation gene-3 (LAG-3; CD223) is an immune checkpoint protein that plays an important role in maintaining autoimmune tolerance and homeostasis. To investigate the cytokine-regulated expression pattern of LAG-3, CD4

Identifiants

DOI: 10.1016/j.jneuroim.2024.578308 PMID: 38325197
pubmed: 38325197
pii: S0165-5728(24)00026-2
doi: 10.1016/j.jneuroim.2024.578308
pii:
doi:

Substances chimiques

Cytokines 0
Interleukin-18 0
Lag3 protein, human 0
IL18 protein, human 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

578308

Informations de copyright

Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest All of the authors declare that there are no conflicts of interest.

Auteurs

Jingluan Tian (J)

Department of Neurology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Xuan Liu (X)

Department of Neurology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Hansi Liang (H)

Jiangsu Institute of Clinical Immunology, Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Yu Shen (Y)

Jiangsu Institute of Clinical Immunology, Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Xuanyi Xiang (X)

Department of Neurology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Feng Zhu (F)

Department of Neurology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Xin Wang (X)

Department of Neurology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Cuiping Liu (C)

Jiangsu Institute of Clinical Immunology, Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Xingshun Xu (X)

Department of Neurology, First Affiliated Hospital of Soochow University, Suzhou 215006, China; Institute of Neuroscience, Soochow University, Suzhou 215031, China.

Xueguang Zhang (X)

Jiangsu Institute of Clinical Immunology, Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Qun Xue (Q)

Department of Neurology, First Affiliated Hospital of Soochow University, Suzhou 215006, China; Jiangsu Institute of Clinical Immunology, Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou 215006, China. Electronic address: qxue_sz@163.com.

Yanzheng Gu (Y)

Jiangsu Institute of Clinical Immunology, Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou 215006, China. Electronic address: gyz_1982@yeah.net.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Expression of lymphocyte activation gene-3 on CD4
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Expression of lymphocyte activation gene-3 on CD4
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-18 › Expression of lymphocyte activation gene-3 on CD4
questionsmedicales.fr › Phénomènes du système immunitaire › Activation des lymphocytes › Expression of lymphocyte activation gene-3 on CD4
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Maladies auto-immunes du système nerveux › Myasthénie › Expression of lymphocyte activation gene-3 on CD4
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Expression of lymphocyte activation gene-3 on CD4