Acute sickle cell hepatopathy: A case report and literature review.
Acute hepatic crisis
Sickle cell disease
Sickle cell hepatopathy
Sickle cell intrahepatic cholestasis
Journal
Journal of the National Medical Association
ISSN: 1943-4693
Titre abrégé: J Natl Med Assoc
Pays: United States
ID NLM: 7503090
Informations de publication
Date de publication:
Apr 2024
Apr 2024
Historique:
received:
20
02
2023
revised:
01
09
2023
accepted:
30
09
2023
medline:
18
3
2024
pubmed:
22
2
2024
entrez:
21
2
2024
Statut:
ppublish
Résumé
Sickle cell disease (SCD) is an inherited hemoglobinopathy with protean clinical manifestations. The liver could be affected by various SCD-associated complications of an overlapping nature. The clinical presentations of "sickle cell hepatopathy" range from clinically asymptomatic patients to those with life-threatening complications. Herein we report an SCD patient who presented with right upper quadrant abdominal pain and jaundice, eventually diagnosed as a self-limited form of acute sickle cell hepatopathy with overlapping features of acute hepatic crisis and benign intrahepatic cholestasis. Using this patient as an illustration, we will review the spectrum of hepatobiliary presentations in the SCD population.
Identifiants
pubmed: 38383222
pii: S0027-9684(23)00111-6
doi: 10.1016/j.jnma.2023.09.013
pii:
doi:
Types de publication
Review
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
119-125Informations de copyright
Copyright © 2024. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no conflict of interest. All authors disclose no financial, professional, or personal conflicts that are relevant to the manuscript.